5th Annual Gulf-Atlantic Veterinary Conference

Update on the Use of Gastroprotectants

Saturday, December 2
2:10 PM - 3:00 PM
Location: Grand Ballroom Salon A


Gastroprotectants include acid suppressants (e.g.histamine-2 receptor antagonists, proton pump inhibitors), antacids (e.g. calcium carbonate, aluminum hydroxide), coating agents (e.g. barium, sucralfate), and prostaglandin analogs (e.g. misoprostol). Gastroprotectants are widely used for the prevention and treatment of inflammatory and ulcerative gastrointestinal diseases. Yet, the evidence to guide the use of these drugs in our veterinary patients is lacking. Thus, until such studies are performed in dogs and cats, practitioners must rely on results of studies performed in humans with GI disease. This presentation will review the available veterinary literature, provide insights from the use of these drugs in human medicine, and, when available, introduce newer gastroprotectant dosing recommendations and indications which may improve the outcome of dogs and cats with and at risk for erosive and ulcerative disease.

M. Katherine Tolbert

Assistant Professor
University of Tennessee College of Veterinary Medicine

Dr. M. Katherine ("Katie") Tolbert is a native of Atlanta, Georgia. She received her Bachelor of Science from Berry College in Rome, Georgia. She completed her veterinary degree as well as a small animal medicine and surgery rotating internship at the University of Georgia. She then completed a small animal internal medicine residency at North Carolina State University. Following her residency, she pursued a doctorate in Comparative Biomedical Sciences at North Carolina State University. She is currently on faculty as an Assistant Professor at the University of Tennessee, College of Veterinary Medicine (UT CVM). In addition to running an extramurally funded lab devoted to clinical and basic gastroenterology research, Dr. Tolbert also has a clinical appointment serving as a small animal internist at the UT CVM. She has a passion for all of the sub-specialties of clinical medicine but particularly enjoys gastrointestinal, immune-mediated, and infectious diseases. Dr. Tolbert’s clinical research program is focused on small animal gastroenterology with a specific interest in the investigation of the efficacy of anti-secretory drugs and gastroprotectants and the rationale for their use in the treatment of acid-related disorders, organ failure, and inflammatory diseases in companion animals. Her basic science research program is dedicated to characterizing the pathogenic mechanisms of feline Tritrichomonas foetus infection and exploring novel therapies to prevent and/or ameliorate T. foetus-induced colitis. Peer-reviewed manuscripts written by the author can be found at: orcid.org/0000-0001-8725-9530.


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Update on the Use of Gastroprotectants


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