Radiation and Cancer Biology

EDU 25 (Live SA-CME) - Translational Genomics to Advance Precision Radiation Oncology

Gene expression-based biomarkers of clinical radiation response

Tuesday, October 23
1:40 PM - 2:00 PM
Location: Room 006

Daniel Spratt, MD

University of Michigan

The University of Michigan Cancer Center: Assistant Professor: Employee, Associate Professor: Employee

Dan Spratt, MD, is an Associate Professor in the Department of Radiation Oncology at the University of Michigan. He is a national leader in genitourinary and spinal malignancies. In addition to his medical training at Vanderbilt University where he obtained his medical degree, he completed his radiation oncology residency at Memorial Sloan Kettering Cancer Center. Dr. Spratt is the Chief of the Genitourinary Radiotherapy Program and Vice Chair of Clinical Research within the Department of Radiation Oncology. He also is the co-chair for the Genitourinary Division of Clinical Research for the Rogel Cancer Center, co-leader of the LAPS U10 cooperative group clinical trial program, is the founder and director the Spine Oncology Program at the University of Michigan, and co-chairs the radiobiology and radiotherapy working group for the Prostate Cancer Foundation. He gives talks nationally and internationally on his work in prostate cancer, and serves on study sections for several federal and foundation programs. Dr. Spratt has published extensively in peer-reviewed journals and has received grant funding on the topics of prostate cancer and spinal malignancies. He has developed novel prognostic models to assess the aggressiveness of a patient’s cancer using not only clinical and pathologic features, but also genomic and imaging biomarkers. His laboratory focuses on the interaction of androgens and DNA repair in prostate cancer and methods to overcome radiation resistance. He runs novel phase I/II clinical trials to improve treatment outcomes and reduce side effects from cancer treatment.


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Gene expression-based biomarkers of clinical radiation response

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