Radiation and Cancer Biology

Panel 06 - The Translational Potential of Liquid Biopsies for Predicting Radiation Response

Mobilization of circulating tumour cells during cancer therapy

Monday, October 22
11:05 AM - 11:25 AM
Location: Room 304

Olga Martin, PhD

Disclosure:
No relationships to disclose.

Biography:
Associate Prof. Olga Martin, PhD, is from Peter MacCallum Cancer Centre, Melbourne, Australia. She obtained her PhD in Cancer Biology in 1993 at the Cancer Research Centre of Russian Federation, Moscow, Russia. In 1994-1999 she had her professional training as a Postdoctoral Fellow in the Department of Nuclear Medicine, Clinical Centre, NIH, Bethesda, USA, where she got involved in molecular cancer and radiation biology research. During more than 10 years in Bill Bonner’s lab at NIH, where the gamma-H2AX assay was discovered, Olga has developed a comprehensive interest and expertise in the field of DNA damage and repair. From this base, she has exploited the particular advantages of the assay (namely exquisite sensitivity and rapidity of DNA damage response) in a wide variety of biological contexts. Thus, Olga’s research and publications have embraced aging, carcinogenesis, cell-cell communication, radiation biology and biodosimetry. More recently, her interests have focused on clinical challenges, particularly in radiation oncology. Since 2011 at Peter MacCallum Cancer Centre, she has been working in collaboration with radiation oncologists on projects related to individual radiosensitivity, detection and separation of circulating tumour cells in the blood stream of cancer patients undergoing radiotherapy, and systemic DNA damage and immune response in cancer patients undergoing radiotherapy, and in mice irradiated with synchrotron radiation.


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