Radiation and Cancer Biology

Panel 16 - Exploiting the DNA Damage Response to Improve the Response to Radiation Therapy

Targeting MDM2 with Radiation

Wednesday, October 24
11:00 AM - 11:20 AM
Location: Room 304

Randall Kimple, MD, PhD

Univeristy of Wisconsin

Disclosure:
Employment
University of Wisconsin: Associate Professor: Employee

Compensation
American Cancer Society: Research Grants; Ascension ventures: Consultant; Igynta: Research Grants; National Institute of Health: Research Grants; Peloton Therapeutics: Research Grants; V Foundation for Cancer Research: Research Grants

Leadership
International Journal of Radiation Oncology Biology Physics: Senior Editor

Biography:
Randy Kimple, MD PhD is an Associate Professor in the Departments of Human Oncology and Medical Physics at the University of Wisconsin School of Medicine and Public Health.

In my clinical practice, I specialize in treating patients with malignancies of the head and neck. I am a member of the UW Multidisciplinary Head and Neck Program and work closely with head and neck surgeons, medical oncologists, radiologists, speech and swallow therapists and other specialists to best meet the individual patient’s needs.

My research laboratory is focused on understanding why cancers don’t always respond to treatment. We use patient-derived xenografts—patient tumor samples grown in animals—to test radiation, chemotherapy and combinations of therapies to understand which characteristics of a patient’s tumor may predict response to treatment. The goal of this work is to enable more personalized treatment and to find ways to combine different treatment methods to decrease treatment side effects without reducing cure rates.

Presentation(s):

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