Special Session

Keynote Address I - Norman Sharpless, MD

NCI Director's Update

Monday, October 22
9:15 AM - 9:35 AM
Location: Stars at Night Ballroom

Norman Sharpless

Disclosure:
Employment
NCI: Director: Employee

Compensation
G1 Therapeutics: Advisory Board; Healthspan: Advisory Board; Pfizer: Honoraria; Unity Biotechnology:: Advisory Board

Ownership
G1 Therapeutics: Stock; Healthspan: Stock; Unity Biotechnology: Patent/License Fees/Copyright, Stock

Leadership
G1 Therapeutics: Founder and Board of Directors; Healthspan: Scientific Advisory Board

Biography:
Norman E. “Ned” Sharpless, M.D., is the 15th director of the National Cancer Institute (NCI), and previously served as the director of the University of North Carolina (UNC) Lineberger Comprehensive Cancer Center. Dr. Sharpless, a Morehead Scholar at UNC–Chapel Hill, received his undergraduate degree in mathematics and went on to pursue his medical degree from UNC School of Medicine where he graduated with honors and distinction in 1993. He then completed his internal medicine residency at the Massachusetts General Hospital and a hematology/oncology fellowship at Dana-Farber/Partners Cancer Care, both of Harvard Medical School in Boston. After 2 years on the faculty at Harvard Medical School, he joined the faculty of the UNC School of Medicine in the Departments of Medicine and Genetics in 2002. He became the Wellcome Professor of Cancer Research at UNC in 2012. Dr. Sharpless is a member of the Association of American Physicians as well as the American Society for Clinical Investigation (ASCI), the nation’s oldest honor society for physician–scientists, and served on the ASCI council from 2011 to 2014. Dr. Sharpless was an associate editor of Aging Cell and deputy editor of the Journal of Clinical Investigation. He has authored more than 150 original scientific papers, reviews, and book chapters, and is an inventor on 10 patents. He cofounded two clinical-stage biotechnology companies: G1 Therapeutics and HealthSpan Diagnostics.
Dr. Sharpless is chief of the Aging Biology and Cancer Section in the National Institute on Aging’s Laboratory of Genetics and Genomics, where he continues his research on the biology of the aging process that promotes the conversion of normal self-renewing cells into dysfunctional cancer cells. Dr. Sharpless has made seminal contributions to the understanding of the relationship between aging and cancer, and in the preclinical development of novel therapeutics for melanoma, lung cancer, and breast cancer.

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