Radiation Physics

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TU_8_3194 - Dosimetric Comparison between single-isocenter RapidArc and multi-isocenter Circular Cone Arc for Radiosurgery to Multiple Brain Metastases

Tuesday, October 23
1:00 PM - 2:30 PM
Location: Innovation Hub, Exhibit Hall 3

Dosimetric Comparison between single-isocenter RapidArc and multi-isocenter Circular Cone Arc for Radiosurgery to Multiple Brain Metastases
P. Dai1, P. Zhang2, L. Luo2, G. Deng2, Q. Huang2, and L. CAI2; 1Gangdong 999 Brain Hospital, Gangzhou city,Guangdong province, China, 2Guangdong 999 Brain Hospital, Guangzhou city ,Guangdong province, China

Purpose/Objective(s): This study compares the dosimetry and efficiency of two stereotactic radiosurgery modalities for multiple brain metastases (single-isocenter RapidArc in and multi-isocenter Circular Cone Arc in iPlan).

Materials/Methods: Ten patients with three to five small brain metastases were used in this study. The size of targets varied from 0.13 to 12.91cc. SRS plans were made using both Circular Cone Arc in iPlan and a single-isocenter, four non-coplanar RapidArc in Eclipse.The prescription for all targets was standardized to 16Gy. Each plan was normalized for 100% prescription dose to 95% to 100% of target volume. Dosimetric parameters analyzed included Paddick conformity indices(CI), gradient indices(GI) and homogeneity indices(HI) for each target, dose falloff as well as the V3,V6,V9,V12 and V16 isodose volumes.

Results: Compared with Cone Arc, four non-coplanar RapidArc improved plan CI (0.79±0.10 vs 0.50±0.22,p = 0.000) and HI(0.07±0.01 vs 0.15±0.07,p = 0.000), with no significant difference in 9Gy (65.60±33.36 vs 54.01±34.47, p = 0.059) and 12Gy isodose volume(32.00±16.87 vs 32.26±21.00, p = 0.445).Cone Arc plans achieved better low-dose spread(≤6Gy,p = 0.005).RapidArc plans were associated with markedly reduced monitor units(MUs).

Conclusion: For multiple brain metastases stereotactic radiosurgery, non-coplanar RapidArc(single-isocenter, four Arcs) has better CI and HI,V12 are comparable. Because of its similar plan quality and increased delivery efficiency, single-isocenter RapidArc radiosurgery has more advantageous than multi-isocenter Circular Cone Arc radiosurgery for some patients.

Author Disclosure: P. Dai: None. P. Zhang: None. G. Deng: None.

Peng Dai, MB, PhD

Biography:
My name is Dai Peng. I graduated from Central South University(Changsha,Hunan) in 2004 with a major in clinical medicine, and graduated from Xuzhou Medical University (Xuzhou,Jiangsu)with a master's degree in oncology in 2010. I have been engaged in oncology clinical work for 6 years. In 2013, I worked in the Oncology Department of Guangdong Sanjiu Brain Hospital (Guangzhou,Guangdong)and began to work as a radiotherapy physicist. I have obtained a doctor's qualification certificate, an intermediate doctor of oncology, and a physicist certificate. Currently, I am mainly engaged in radiotherapy planning for neurological tumors, head and neck tumors, and radiobiology related research. Email: dazzle1980@163.com

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TU_8_3194 - Dosimetric Comparison between single-isocenter RapidArc and multi-isocenter Circular Cone Arc for Radiosurgery to Multiple Brain Metastases



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