Gastrointestinal Cancer

EDU 34 - (INTERACTIVE) Cancer of the Colon, Rectum, and Anus

10/24/2018
7:45 AM - 9:00 AM
Location: Room 206

Session Type: Educational
1.25 AMA PRA Category 1 Credits™
1.25 CAMPEP Credits
1.50 MDCB Credits

Rectal Cancer (Goodman): Chemoradiation (CRT) remains the current standard management approach in the neoadjuvant setting for stage II and III rectal cancer and as definitive sphincter-preserving therapy for anal canal cancer. Local regional control rates with the use of CRT are
quite good, but results are tempered by both acute and late morbidity. To reduce the toxicities of both standard as well as investigational CRT combinations, the use of intensity modulated radiotherapy is under investigation. In this educational session we will discuss both the standard and investigational CRT strategies for these lower-gastrointestinal malignancies, including their associated toxicities, and demonstrate the underlying techniques and potential impact of conformal radiotherapy as part of the multidisciplinary treatment.

Anal Cancer (Anwar): Radiation therapy has played an essential role in the curative management of anal cancer since the landmark work of Nigro, over 40 years ago; yet both technology and therapeutic agents have evolved significantly since then. This portion of the colorectal and anal session will focus on treatment of anal cancers, spanning high-grade dysplasia to locally advanced anal cancer, with emphasis on treatment strategies using IMRT. Furthermore, due to the toxicities for chemoradiation in this setting, we will outline strategies for patient symptom management, something vital to ensuring completion of therapy without undue breaks. We will also discuss the role of various chemotherapy regimens in concert with radiation therapy and the importance of total treatment time. Additionally emphasis will be given to one of our more challenging treatment populations, HIV positive patients.

Learning Objectives:

Presentations:

Karyn Goodman, MD, MS

University of Colorado Cancer Center

Disclosure:
Employment
University of Colorado School of Medicine: Professor: Employee

Compensation
RenovoRx: Consultant

Biography:
Dr. Karyn Goodman is a Professor in the Department of Radiation Oncology at the University of Colorado and serves as the Associate Director of Clinical Research in the University of Colorado Cancer Center. She moved to University of Colorado from the Memorial Sloan-Kettering Cancer Center in New York in 2015. Dr. Goodman obtained her undergraduate and medical degrees from Stanford University. She completed her residency training in Radiation Oncology at Memorial Sloan-Kettering Cancer Center and earned a Masters in Epidemiology at the Harvard School of Public Health in 2006. Dr. Goodman’s interests include image-guide radiation therapy, stereotactic body radiotherapy, and intensity modulated radiotherapy treatment planning for gastrointestinal cancers with the intent of reducing toxicity and improving results with radiation therapy. She has also focused her research on quality of life and late effects after radiotherapy. In addition to her interest in technical advances in radiation oncology, she is involved in the development of therapeutic protocols combining radiation, chemotherapy, targeted agents, and immunotherapy for gastrointestinal cancers. Dr. Goodman is an internationally recognized expert in Gastrointestinal Cancer and has served in numerous leadership roles on multiple national committees. She serves as the principal investigator of several national studies as well as numerous institutional studies at the University of Colorado. She has been a leader in developing SBRT for gastrointestinal cancers and continues to evaluate the combination of SBRT with other treatment modalities. She has published over 150 peer-reviewed scientific articles, review articles, and chapters.

Presentation(s):

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