Anas Raed, MD
MD
Augusta University
Augusta, GA
Anas Raed, MD1, Jigar Bhagatwala, MBBS1, Muhammed Sherid, MD1, Supannee Rassameehiran, MD2, Humberto Sifuentes, MD2, Amol Sharma, MBBS1, Subbaramiah Sridhar, MD3
1Augusta University, Augusta, GA; 2Medical College of Georgia at Augusta University, Augusta, GA; 3Georgia Medical College / Augusta University, Augusta, GA
Introduction: Liver and intrahepatic bile duct cancer are the second aggressive cancer with 5-year survival rate of 18%. Also, they are the fourth most common cause of GI malignancy, and there incidence has tripled since 1980. Hence, our objectives were to study incidence trends of liver cancer (LC) by geographic location, specifically by regions and states.
Methods: Data was extracted from National Program of Cancer Registries (NPCR) and Surveillance, Epidemiology and End Results (SEER) for the period 2001-2015. Age-adjusted incidence and annual percent change (APC) were calculated in a step-wise manner to examine the trends among each of four US regions, followed by 13 individual SEER-reported states. SEER Stat software was used to analyze this data.
Results: The incidence rates of LC in population younger than 50 years have been trending in all US regions. When reporting incidence rates of LC in population younger than 50 years by states, the rates have been trending down in all US states except state of Kentucky and Iowa which rates have been increasing with APC of 2.8 (CI: 0.7, 5.0), 2.7 (CI: 0.2, 5.3), respectively (table 2). The incidence rates of LC in population 50 years or older have been increasing the in all US regions with highest rates in South with APC of 5.2 (CI: 4.8, 5.6) (table 1). When reporting incidence rates of LC in population 50 years or older by states, the rates was the highest in state of Utah and Kentucky with APC of 7.1 (CI: 5.9, 8.4) and 6.6 (CI: 5.8, 7.3), respectively.
Discussion: This epidemiological data shows the disparities of LC by geographic location. Our outcomes of geographical variation of incidence rates of LC may help to initiate programs to target high risk regions and states.
Citation: Anas Raed, MD; Jigar Bhagatwala, MBBS; Muhammed Sherid, MD; Supannee Rassameehiran, MD; Humberto Sifuentes, MD; Amol Sharma, MBBS; Subbaramiah Sridhar, MD. P1528 - REGIONAL DISPARITIES AND TRENDS OF LIVER CANCER IN THE USA: SHEDDING LIGHTS ON POTENTIAL PREVENTABLE LETHAL DISEASE. Program No. P1528. ACG 2019 Annual Scientific Meeting Abstracts. San Antonio, Texas: American College of Gastroenterology.