Topical Area: Medical Nutrition
Objectives : In this study we want to investigate the effects of Q-CAN® Plus, the nutritional fermented soy drink on the hematological parameters in lean and obese individuals.
Methods : Prospective study comprised of lean (10) and obese (10) individuals without a known diagnosis. 11 clinic visits over 14 weeks (visit 1/wk -2, visit 2/wk -1, visit 3/wk 0, visit 4/wk 1, visit 5/wk 2, visit 6/wk 3, visit 7/wk 4, visit 8/wk 6, visit 9/wk 8, visit 10/wk 10, visit 11/wk 12). Visits 1, 2 and 3 occurred prior to treatment. 237ml of soy was dispensed at visit 3 and was consumed twice daily for 4 weeks until visit 7 (weeks 1-4). Visits 8, 9, 10 and 11 were post treatment. Blood was collected during visits 1, 3, 5, 7, 8, 9, 10,11, and various hematological parameters were quantified at Yale New haven health, hematology lab at the Department of laboratory medicine (Yale new haven health, Yale University, CT, USA). The values were statistically analyzed using one-way ANOVA and the results were considered significant for P< 0.05.
Results : Various blood indices such as mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), mean platelet volume (MPV), red blood cell distribution width (RDW-CV), hematocrit, RBC count, WBC count, % neutrophils, average number of neutrophils (# neutrophils), % monocytes, % basophils, average number of lymphocytes (# lymphocytes), % eosinophils and C- reactive protein were analyzed. These values were compared as plot curve for values from individual visits of each subject, as averages of combined values of both lean and obese individuals grouped as (pre, during and post) treatment periods of BESO soy drink, as averages of lean vs obese grouped for various treatment periods of BESO soy drink and as ratio of averages of lean vs obese group values for various treatment periods of BESO soy drink. The consumption of Q-CAN® Plus did not result in significant changes in any hematological parameters
Conclusions : Q-CAN® Plus fermented soy drink does not induce any significant change in the hematological parameters of both lean and obese individuals. These observations demonstrate the safety of Q-CAN® Plus regarding hematological parameters in lean and obese individuals.
Funding Sources : Beso Biological Research, Inc.