Presentation Authors: peng zhou*, JINGYU ZHU, RUIPENG LI, HANGZHOU, China, People's Republic of
Introduction: To properly use the Ureteric Symptom Score Questionnaire (USSQ) to evaluate, in a randomized control study, the effect of tamsulosin, solifenacin, and their combination in improving symptoms and quality of life in patients with indwelling ureteral stents.
Methods: After institutional review board approval, 260 patients with a ureteral stent were randomly assigned to receive tamsulosin 0.4â€‰mg, solifenacin 5â€‰mg, or placebo and further randomized to receive their combination. The validated USSQ was completed 1 and 4 weeks after stent insertion and 4 weeks after stent removal. Kruskal-Wallis test, chi-squared test (or Fisher's exact test), one-way analysis of variance, and T-test (or Wilcoxon rank-sum test if not normal data) were used for statistical analysis. The results were considered significant at pâ€‰
Results: Patients receiving tamsulosin or solifenacin expressed significantly lower urinary (pâ€‰
Conclusions: Stent-related morbidity is a reality in the majority of patients. Simple medication, such as tamsulosin and solifenacin alone or in combination, improves stent-related symptoms and has a positive impact on quality of life.