Presentation Authors: Benedetta Valli, Guido Barbagli, Sofia Balò, Arezzo, Italy, Massimo Lazzeri*, Rozzano, Italy
Introduction: There is scant information about the incidence of urinary tract infection in men with urethral strictures. The aim of this study was to investigate the prevalence and phenotypes of pathogens among adult patients with urethral stricture diseases.
Methods: This is a cross-sectional study, which was conducted at a high volume tertiary center for the management of urethral diseases between September 2014 to December 2015. Cases of interest were all the adult patients with urethral stricture diseases, who were scheduled for surgery and underwent a urine samples before the surgery. The primary end-point was to determine the prevalence of urinary tract infection, defined as a urine culture positive: 1 Ã— 105 colony forming units/ml. The secondary end-point was to investigate the phenotypes of isolated pathogens.
Results: Overall 386 patients (mean age 56,6 years, range 14 - 84) were included in the study. The prevalence of urinary tract infection was 32.1% (124/386); the highest prevalence was observed in age range between 60-69 years, while the lowest in younger men. The most frequent phenotype was E. coli 46% (57/124), followed by Enterococcus 21% (26/124). All data are summarized in table 1 and 2.
Conclusions: We found a high prevalence of UTI in men with urethral stricture, who were scheduled for surgery. The prevalence was higher in elderly patients than in younger and the most frequent pathogen was E. Coli followed by the Enterococcus. Both the observation could have clinical implications and prompt further genotyping studies.