Presentation Authors: Antonio Luigi Pastore*, Andrea Fuschi, Lorenzo Capone, Gennaro Velotti, Alessia Martoccia, Yazan Al salhi, Latina, Italy, Ester Illiano, Elisabetta Costantini, Terni, Italy, Antonio Carbone, Latina, Italy
Introduction: The aim of the study was to evaluate the long-term(48 months follow-up)outcomes of pelvic floor muscle (PFM) rehabilitation in males suffering from lifelong premature ejaculation (PE). The patients were all investigated using intravaginal ejaculatory latency time (IELT) and the self-report Premature Ejaculation Diagnostic Tool (PEDT) to evaluate clinical outcomes.
Methods: A total of 216 participants were retrospectively reviewed in this study, with 174 completing the training protocol. At baseline, all participants had an IELT â‰¤60 s and PEDT score >11. Participants completed a 12-week program of PFM rehabilitation, including physio-kinesiotherapy treatment, electrostimulation, and biofeedback, with three sessions per week, with 20 min for each component completed at each session. The effectiveness of intervention was evaluated by comparing the change in the geometric mean of IELT and PEDT values, from baseline, at 3, 6, and 12 months during the intervention, and at 24, 36 and 48 months postintervention, using a paired sample 2- tailed t-test, including the associated 95% confidence intervals.
Results: Of the 174 participants who completed PFM rehabilitation, 151 gained control of their ejaculation reflex, with a mean IELT of 172.9 s and PEDT score of 2.6 at the 12-week endpoint of the intervention, representing an increase from baseline of 41.6 s and 16.0 scores, respectively, for IELT and PEDT (P < 0.0001). Of the 109 participants who completed the 48-month follow-up, 68% and 52% maintained satisfactory ejaculation control at 36 and 48 months post-intervention, respectively. None patients reported side effects.
Conclusions: To the best of our knowledge, the present study has the longest follow-up period (48 months) reported to date for any intervention for PE. There is a lack of standardized measures to assess improvement following the PFM intervention, with the treatment parameters difficult to define as they are largely based on sensory perception. Nonetheless, there is a continued need for evidence-based research to validate the role of physiokinesiotherapy in the treatment of PE. Although the type, the amount, and the focus (relaxation, strength, support, or control) of exercise required have not yet been standardized, our long-term results suggest that it may be considered as a valid therapeutic option for patients with PE.