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Exhibit and Poster Reception (authors present)
Tuesday, Jun 18
6:15 pm

Opening Exhibit and Poster Reception (authors present)
Location: Salon E, 4th Floor
Sponsored By:
Tuesday, Jun 18
6:15 pm

T. 1 - The Incidence of Cancer in Giant Cell Arteritis: A Single Center Study
Maushmi Savjani, MD – Penn State Hershey College of Medicine; Vincent Aluquin, MD – Penn State Hershey College of Medicine; Shirley Albano-aluquin, MD – Penn State Hershey College of Medicine
Tuesday, Jun 18
6:15 pm

T. 2 - A Novel NLRC4 Mutation Leads to Elevated IL-18 without Increased Caspase-1 Activation in a Lupus Patient with Macrophage Activation Syndrome
Justin Branch, BS – Baylor College of Medicine; Beatriz Bolivar, PhD – Baylor College of Medicine; Phillip Baker, BS – Baylor College of Medicine; Olive Eckstein, MD – Baylor College of Medicine; Lisa Forbes Satter, MD – Baylor College of Medicine; Andrea Ramirez, MD – Baylor College of Medicine; Lisa Bouchier-Hayes, PhD – Baylor College of Medicine; Tiphanie Vogel, MD PhD – Baylor College of Medicine
Tuesday, Jun 18
6:15 pm

T. 3 - ANCA Associated Vasculitis Following Related Bone Marrow Transplantation
Sharanya Joginpalli, MD – Texas Tech University Health Sciences; John S. Pixley, MD – Texas Tech University Health Science Center
Tuesday, Jun 18
6:15 pm

T. 4 - Autoinflammatory syndrome, secondary to de novo variant in CDC42 (p.C188Y), improved with IL-1b inhibition.
Yael Gernez, MD PhD – Department of Pediatrics, Allergy, Immunology and Rheumatology at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Claudia Macaubas, PhD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Matthew Kirkey, PhD – Department of Pediatrics, Stem Cell Transplantation, at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Jay M. Balagas, MD – Department of Pediatrics, Hematology/Oncology, 2018 John Muir Health Physician Network Member. Walnut Creek, CA, USA; Scott Canna, MD PhD – Department of Pediatrics, Rheumatology/RK Mellon Institute, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pa, USA; Rosa Bacchetta, MD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; David B. Lewis, MD – Department of Pediatrics, Allergy, Immunology and Rheumatology at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Elizabeth Mellins, MD PhD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Katja Gabriele. Weinacht, MD PhD – Department of Pediatrics, Stem Cell Transplantation, at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Tuesday, Jun 18
6:15 pm

T. 5 - Computational Analysis of Citrulline-Specific CD4+ T Cell Frequency and Phenotype Reveals Differences that are Driven by Antigen Specificity and Disease Characteristics Among Rheumatoid Arthritis Patients
Virginia Muir, Ph.D. – Benaroya Research Institute at Virginia Mason; Cliff Rims, B.S. – Benaroya Research Institute at Virginia Mason; Hannes Uchtenhagen, Ph.D. – Benaroya Research Institute at Virginia Mason; Anne Hocking, Ph.D. – Benaroya Research Institute at Virginia Mason; Sylvia Posso, MSE – Benaroya Research Institute at Virginia Mason; Heather Bukiri, M.D. – Virginia Mason Medical Center; Jeffrey Carlin, M.D. – Virginia Mason Medical Center; Bernard Ng, MBBS, MSc, MMed – VA Puget Sound Health Care System; Eddie James, Ph.D. – Benaroya Research Institute at Virginia Mason; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; Jane H. Buckner, M.D. – Benaroya Research Institute at Virginia Mason
Tuesday, Jun 18
6:15 pm

T. 6 - Cytokine dependence of enthesis-resident lymphocytes in murine spondyloarthritis
Mederbek Matmusaev, MD – Brigham and Women's Hospital; Emma Haley – Brigham and Women's Hospital; Micah Lefton – Brigham and Women's Hospital; Imtiyaz Hossain – Brigham and Women's Hospital; Joerg Ermann, MD – Brigham and Women's Hospital
Tuesday, Jun 18
6:15 pm

T. 8 - Detection of Patients with Systemic Lupus Erythematosus in Electronic Health Records Using Clinical Classification Criteria Based Algorithms
Theresa L. Walunas, PhD – Northwestern University; Anika S. Ghosh, MS – Northwestern University; Jennifer A. Pacheco, MS – Northwestern University; Kathryn L. Jackson, MS – Northwestern University; Anh H. Chung, BS – Northwestern University; Daniel L. Erickson, MBA – Northwestern University; Karen A. Mancera-Cuevas, MS, MPH, CHES – Northwestern University; Abel N. Kho, MD, MS – Northwestern University; Rosalind Ramsey-Goldman, MD, DrPH – Northwestern University
Tuesday, Jun 18
6:15 pm

T. 9 - Differential expansion of Innate-lymphoid populations in Spondyloarthritis and Crohn’s Disease
Adam R. Lefferts, B.S. – University of Colorado, Denver; Emilie Regner, M.D – University of Colorado, Denver; Rebecca O'Rourke, P.H.D – University of Colorado, Denver; Andrew Stahly, M.P.H – University of Colorado, Denver; Kenneth Jones, P.H.D – University of Colorado School of Medicine; Kristine Kuhn, M.D. P.H.D – University of Colorado, Denver
Tuesday, Jun 18
6:15 pm

T. 10 - Early Rheumatoid Arthritis (eRA) is a Perturbation of the Architecture of the Immunome: a System Biology Approach
Chin Teck Ng – Translational Immunology Institute/Singapore Health Services Pte Ltd; Kumar Pavanish – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Monika Mehta – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre; Ahmad Bin Mohamed Lajam – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre; Andrea Low – Singapore General Hospital/ SingHealth Pte Ltd; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre
Tuesday, Jun 18
6:15 pm

T. 11 - Effects of the Malondialdehyde-Acetaldehyde Adduct (MAA) on Biological Responses to Citrullinated Proteins
Geoffrey M. Thiele, Ph.D. – University of Nebraska Medical Center; Michael J. Duryee, M.S. – University of Nebraska Medical Center; Lynell W. Klassen, M.D. – University of Nebraska Medical Center; James R. O'Dell, M.D. – University of Nebraska Medical Center; Bryant R. England, M.D. – University of Nebraska Medical Center; Ted R. Mikuls, M.D./M.S.P.H. – University of Nebraska Medical Center
Tuesday, Jun 18
6:15 pm

T. 12 - Estrogen Controls the Expression of Serine/Arginine-rich Splicing Factor 1 (SRSF1) at the Transcriptional and Post-transcriptional Levels in Human T lymphocytes
Melissa Carr-Reynolds, MS – Beth Israel Deaconess Medical Center, Harvard Medical School; Julian F Oviedo, BA, BS – Beth Israel Deaconess Medical Center, Harvard Medical School; Elena N Cravens, BA – Beth Israel Deaconess Medical Center, Harvard Medical School; Vaishali R. Moulton, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 13 - Towards a data-driven approach to dissect interactions between diet and autoimmunity
Leonardo Ferreira, PhD – UCSF; Iosif Gershteyn, M.A.
Tuesday, Jun 18
6:15 pm

T. 14 - Extensive Immunophenotypic analysis of co-inhibitory an co-stimulatory molecules in Juvenile Idiopathic Arthritis (JIA) peripheral lymphocytes
Estefania Quesada-Masachs – La Jolla Institute for Immunology; Daniel Alvarez-Sierra – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Antoni Julià – Grup de Recerca de Reumatologia (IRHVH); Mónica Martínez-Gallo – Vall d'Hebron University Hospital (HUVH); Ricardo Pujol-Borrell – Vall d'Hebron University Hospital (HUVH); Consuelo Modesto – Vall d'Hebron University Hospital (HUVH); Sara Marsal-Barril – Vall d'Hebron University Hospital (HUVH)
Tuesday, Jun 18
6:15 pm

T. 15 - Failed STAT4 Downregulation Underlies the Pathogenicity of SLE-associated Variants
Ada Ramírez-Sánchez – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Paola Sansón-Tinoco – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Iris K. Madera-Salcedo, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Noé Rodríguez-Rodríguez, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Marta Alarcón-Riquelme, MD, PhD – Genyo; Jose C. Crispin, MD, PhD – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran; Florencia Rosetti, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Tuesday, Jun 18
6:15 pm

T. 16 - Glutaminase 1 is a target for Th17-related autoimmune diseases
Michihito Kono, MD., PhD – Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Hokkaido University/ Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Nobuya Yoshida, MD., PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Kayaho Maeda, MD., PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Abel Suárez-Fueyo, PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Vasileios Kyttaris, MD, PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; George Tsokos, MD. – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 17 - Granzyme K+ CD8 T Cells are Highly Enriched and Have Pro-inflammatory Effects in Synovium and Synovial Fluid in Rheumatoid Arthritis
Anna Helena Jonsson, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Gerald FM. Watts, M.Sc. – Brigham and Women's Hospital; Kevin Wei, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Deepak Rao, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Michael B. Brenner, MD – Brigham and Women's Hospital/Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 18 - Human genetic variation within the MHC influences the hypervariable region of T cell receptor
Kazuyoshi Ishigaki, MD, PhD – Brigham and Women's Hospital; Yang Luo, PhD – Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 19 - In Situ Lymphocyte and Dendritic Cell Characterization in Idiopathic Inflammatory Myopathies
Iazsmin Ventura, M.D. – University of Chicago; Daniel Reilly, Ph.D. – University of Chicago; Peter Pytel, M.D. – University of Chicago; Vladimir M. Liarski, M.D., M.Sc. – University of Chicago
Tuesday, Jun 18
6:15 pm

T. 20 - Integration of single cells from inflamed tissue in RA and SLE reveals shared immune and stromal cell populations
Fan Zhang, PhD – Harvard Medical School; Joseph Mears – Harvard Medical School; Kevin Wei, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Ilya Korsunsky, PhD – Harvard Medical School; Deepak Rao, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Evan Der – The Rockefeller University; Arnon Arazi – Broad Institute; Jill Buyon – NYU Langone Health; Chaim Putterman – Albert Einstein College of Medicine; Thomas Tuschl – The Rockefeller University; Nir Hacohen – Broad Institute; Betty Diamond, MD – Feinstein Institute for Medical Research; Michael B. Brenner, MD – Brigham and Women's Hospital/Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 21 - A New Multiplex Immunoassay Panel for Simultaneous Quantification of Major Metabolic Mediators
Amy Zhao – BioLegend; Nowshin Tabassum – BioLegend; Jason Lehmann – BioLegend; Binggang Sun – BioLegend; Weiping Jiang – BioLegend; Shaoquan Ji – BioLegend
Tuesday, Jun 18
6:15 pm

T. 22 - A Soluble Antigen Array Vaccine Prevents Autoimmune Diabetes
Rebuma Firdessa Fite, DVM, PhD – Columbia Center for Translational Immunology and Department of Medicine, Columbia University Medical Center; Martin Leon, PhD – Department of Pharmaceutical Chemistry, Department of Chemical and Petroleum Engineering, University of Kansas; Joshua Sestak, PhD – Orion Bioscience Inc; Cory Berkland, PhD – Department of Pharmaceutical Chemistry, Department of Chemical and Petroleum Engineering, University of Kansas; Remi Creusot, PhD – Columbia University Medical Center
Tuesday, Jun 18
6:15 pm

T. 23 - Anti-CD45RC mAb Immunotherapy Controls the Development of Auto-Immune Symptoms in an APECED Rat Model of AIRE Deficiency
Marine Besnard, Ph.D student – Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), LabEx IGO “Immunotherapy, Graft, Oncology”, Nantes, France; Jason Ossart, Ph.D – Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), LabEx IGO “Immunotherapy, Graft, Oncology”, Nantes, France; Claire Usal, research assistant – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Université de Nantes, Nantes, France; Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Nadège Vimond, research assistant – Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), LabEx IGO “Immunotherapy, Graft, Oncology”, Nantes, France; Hadrien Regue, student – Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), LabEx IGO “Immunotherapy, Graft, Oncology”, Nantes, France; Léa Flippe, Ph.D student – Centre de Recherche en Transplantation et Immunologie UMR 1064 INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie (ITUN), LabEx IGO “Immunotherapy, Graft, Oncology”, Nantes, France; Ignacio Anegon – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Annamari Ranki, Pr, MD – HUCH Inflammation Center, Skin and allergy hospital, Helsinki University Central Hospital, Helsinki, Finland; Part Peterson, Ph.D – Molecular Pathology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia; Carole Guillonneau – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO
Tuesday, Jun 18
6:15 pm

T. 24 - Antigen-specificities of Expanded clones of Islet Antigen-Reactive CD4+ T cells from Type 1 Diabetes versus Healthy Subjects
Fariba Whitman, Ph.D. – Benaroya Research Institute; Janice Chen – Benaroya Research Institute; Hannah DeBerg, PhD – Benaroya Research Institute; Alex Hu, Ph.D. – Benaroya Research Institute; Kaitlin Flynn, Ph.D. – Benaroya Research Institute; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; Vivian Gersuk, Ph.D. – benaroya research Institute; Carla Greenbaum, MD – Benaroya Research Institute; Karen Cerosaletti, Ph.D. – benaroya Research Institute; Cate Speae, Ph.D. – Benaroya Research Institute
Tuesday, Jun 18
6:15 pm

T. 26 - Co-Stimulation Blockade Uncouples the Relationship Between C-Peptide Decline and Changes in CD4+ and CD8+ T-Cell Subpopulations
Martin Eichmann, PhD – King's College London; Roman Baptista – King's College London; Mark Peakman, PhD – King's College London; Craig A. Beam, PhD – Western Michigan University
Tuesday, Jun 18
6:15 pm

T. 27 - DNA demethylase TET2 in the life and death of pancreatic beta-cells
Jinxiu Rui, Ph.D – Yale Immunology; Songyan Deng, MD – Yale school of medicine; Gerald Ponath, Ph.D – Yale School of medicine; Maya Levine-Ritterman – Yale school of medicine; Ana Luisa Perdigoto, MD, PhD – Yale University; Jun Lu, Ph.D – Yale School of Medicine; Kevan Herold, MD – Yale Univeristy
Tuesday, Jun 18
6:15 pm

T. 28 - Effect of human probiotic bacteria on development of type 1 diabetes (T1D) in SPF and gnotobiotic NOD mice; mechanisms of mucosal immunity
David P. Funda – Inst. Microbiology AS CR; Hana Kozáková – Inst. Microbiology AS CR; Karsten Buschard – Bartholin Inst.; Tomáš Hudcovic – Inst. Microbiology AS CR
Tuesday, Jun 18
6:15 pm

T. 29 - Engineering Erythrocytes with the SQZ Cell Therapy Platform to Induce Immune Tolerance
Kathy Seidl; Finola Moore, PhD – SQZ Biotechnologies; Alfonso Vicente-Suarez, PhD – SQZ Biotechnologies; Thomas Lee, PhD – SQZ Biotechnologies; Amritha Ramakrishnan, PhD – SQZ Biotechnologies; Lindsay Moore – SQZ Biotechnologies; Brendan Bedard – SQZ Biotechnologies; Howard Bernstein, MD/PhD – SQZ Biotechnologies
Tuesday, Jun 18
6:15 pm

T. 30 - Follicular Regulatory T Cells are Increased in the Peripheral Blood of Subjects with Multiple Islet-Autoantibodies but are Reduced in the Pancreatic Lymph Nodes and Spleen of Patients with Type 1 Diabetes
Andrea Vecchione – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Kimberly Shankwitz – Tissue Analysis Core, Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Jolanda Gerosa – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Tatiana Jofra – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Di Fonte Roberta – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Maria Pia Cicalese – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Andrew Schultz – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Vincenzo Napoleone – Biodigita; Howie Seay – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Davide Cittaro – Center for Translation Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute; Donatella Biancolini – Center for Translation Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute; Francesca Ragogna – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Angela Stabilini – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Pauline Grogan – TrialNet Clinical Center, IRCCS San Raffaele Hospital; Eleonora Bianconi – TrialNet Clinical Center, IRCCS San Raffaele Hospital; Clara Bonura – Department of Paediatrics and Neonatology, IRCCS San Raffaele Hospital; Riccardo Bonfanti – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Andrea Laurenzi – Department of Internal Medicine, IRCCS San Raffaele Hospital; Giulio Frontino – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Rita Nano – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Raffaela Melzi – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Maurizio De Pellegrin – Department of Paediatric Orthopaedics, IRCCS San Raffaele Hospital; Franco Meschi – Department of Internal Medicine, IRCCS San Raffaele Hospital; Matteo Trimarchi – Department of Otorhinolaryngology-Head and Neck Surgery, IRCCS San Raffaele Hospital, Vita-Salute University; Alessandro Borghesi – Neonatal Intensive Care Unit, Fondazione IRCCS Policlinco San Matteo; Emanuele Bosi – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Lorenzo Piemonti – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Alessandro Aiuti – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Todd M. Brusko, Ph.D. – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Constantinos Petrovas – Tissue Analysis Core, Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Manuela Battaglia, PhD – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Georgia Fousteri – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute
Tuesday, Jun 18
6:15 pm

T. 31 - Genetically Engineered Tolerogenic Dendritic Cells for Antigen-specific Immunotherapy of Type 1 Diabetes
Laura Passerini – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Grazia Andolfi – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Virginia Bassi – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) & University of Tor Vergata, Rome, Italy; Andrea Annoni – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Silvia Gregori, Member Number: 36467805 – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
Tuesday, Jun 18
6:15 pm

T. 32 - IL-17A-IL-17R signaling in photoreceptors enhances retinal oxidative stress and the onset of diabetic retinopathy
Sarah I. Lindstrom, BS – Case Western Reserve University-School of Medicine; Thomas E. Zapadka – Case Western Reserve University-School of Medicine; Dawn G. Smith, BS – Case Western Reserve University-School of Medicine; Brooklyn E. Taylor – Case Western Reserve University-School of Medicine; Chieh A. Lee, BS – Case Western Reserve University-School of Medicine; Patricia R. Taylor, PhD – Case Western Reserve University-School of Medicine
Tuesday, Jun 18
6:15 pm

T. 33 - Increased Type 1 Diabetes Incidence Follows the Loss of the Sarco/Endoplasmic Reticulum Ca2+ ATPase in the β cell
Robert N. Bone, PhD – Indiana University School of Medicine; Solaema Taleb, MS – Indiana University School of Medicine; Xin Tong, PhD – Vanderbilt University; Tatsuyoshi Kono, PhD – Indiana University School of Medicine; Ivan Gerling, PhD – University of Tennessee Health Science Center; Carmella Evans-Molina, MD/PhD – Indiana University School of Medicine
Tuesday, Jun 18
6:15 pm

T. 34 - Induced Pluripotent Stem Cells for Type 1 Diabetes In Vitro Modeling and Immunoprotection of β cells
Nayara Carvalho. Leite, PhD – Harvard University; Elad Sintov, PhD – Harvard University; Douglas Melton, PhD – Harvard University
Tuesday, Jun 18
6:15 pm

T. 35 - Inhibiting IL-7 Signaling Modulates T-cell Metabolism in NOD Mice
Albert Jones, IV, MA – Boston University School of Medicine; Pranav Meka – Boston University School of Medicine; Hans Dooms, PhD – Boston University School of Medicine
Tuesday, Jun 18
6:15 pm

T. 36 - Interleukin-17A transcellular signaling induces diabetic retinopathy
Patricia R. Taylor, PhD – Case Western Reserve University-School of Medicine; Sarah I. Lindstrom, BS – Case Western Reserve University-School of Medicine; Thomas E. Zapadka – Case Western Reserve University-School of Medicine; Haitao Liu, BS – Case Western Reserve University-School of Medicine; Jie Tang, MS – Case Western Reserve University-School of Medicine; Chieh A. Lee, BS – Case Western Reserve University-School of Medicine; Brooklyn E. Taylor – Case Western Reserve University-School of Medicine; Timothy S. Kern, PhD – Case Western Reserve University-School of Medicine
Tuesday, Jun 18
6:15 pm

T. 37 - LV.InsulinB9-23/Anti-CD3 Combined Therapy Inhibits Recurrence Of Autoimmunity In NOD Mice After Allogeneic Pancreatic Islets Transplant
Fabio Russo – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Giorgia Squeri – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Francesca Sanvito – Pathology Unit, Ospedale San Raffaele; Silvia Gregori, Member Number: 36467805 – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Maria Grazia Roncarolo, MD PhD – Stanford University; Andrea Annoni – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
Tuesday, Jun 18
6:15 pm

T. 38 - Dynamic gene regulatory network of IFNbeta response in human T cells
Tomokazu A. Sumida, MD, PhD – Yale School of Medicine; Matthew Lincoln, MD, PhD – Yale School of Medicine; Chinonso Ukeje – Yale School of Medicine; Pierre-Paul Axisa, DVM, PhD – Yale School of Medicine; David Hafler, MD – Yale School of Medicine
Tuesday, Jun 18
6:15 pm

T. 39 - Extended Poly-dimensional Immunome Characterization (EPIC): A Web-based Immune Reference Atlas of the Healthy Human Immunome and a Tool for Translational Medicine
Joo Guan Yeo, PhD, MBBS, MMed (Paediatrics), MRCPCh (UK) – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Pan Lu – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Martin Wasser, PhD, MTech-KE – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre; Kumar Pavanish – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Thaschawee Arkachaisri, MD, FACR – KK Women’s and Children’s Hospital; Su Li Poh – Translational Immunology Institute/SingHealth Duke-NUS Academic Medical Centre; Fauziah Ally – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Jing Yao Leong, PhD – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Kee Thai Yeo, MD CM (McGill U, Canada), Diplomate of the American Board of Pediatrics (General Pediatrics, Neonatal-Perinatal Medicine, Pediatric Infectious Diseases) – Translational Immunology Institute/ SingHealth Duke-NUS Academic Medical Centre; Liyun Lai – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Angela Yun June Tan, MBBS, MMed (Anaes) – KK Women's and Children's Hospital; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre
Tuesday, Jun 18
6:15 pm

T. 40 - Flu Antigen Recall Responses using TruCulture® with OptiMAP Analysis
Shen-An Hwang, PhD – Myriad RBM; Dominic Eisinger, PhD – Myriad RBM; Samuel Labrie, PhD – Myriad RBM
Tuesday, Jun 18
6:15 pm

T. 42 - Immunomonitoring of HLA-DR expression and ratio nCD64/mHLA-DR as predictive biomarkers of infection in critical patients at the Intensive Care Unit
Bibiana Quirant-Sánchez, MSc – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Ester Lucas-Varas, MSc – mmunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona; Oriol Plans-Galván, MD – Intensive Care Unit, Hospital Germans Trias i Pujol, Badalona; Fernando Armestar-Rodríguez, PhD – Intensive Care Unit, Hospital Germans Trias i Pujol, Badalona; Eva M Martinez-Caceres, PhD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra
Tuesday, Jun 18
6:15 pm

T. 43 - Inclusion of exploratory PD biomarkers in First in human clinical trials adds value by providing information to confirm the mode of action of a candidate therapeutic.
Elisa Masat, PhD – Charles River Laboratories; Christopher Kirkham – Charles River Laboratories; Clare Hetheridge – Charles River Laboratories; Charlotte Hayden – Charles River Laboratories; Tommaso Ianniti – Charles River Laboratories; Russell Garland – Charles River Laboratories; Neil A. Williams, PhD – Charles River Laboratories; Rhiannon Jenkinson, PhD – Charles River Portishead
Tuesday, Jun 18
6:15 pm

T. 44 - LPS induced neuroinflammation assay combination for development of new treatment strategies
Gunnar Flik – Charles River Laboratories; Mariette Heins – Charles River Laboratories; Pekka Poutiainen – Kuopio University Hospital; Tuulia Huhtala – Charles River Laboratories Discovery
Tuesday, Jun 18
6:15 pm

T. 45 - MHC II dCODE Dextramer reagents allow characterization of antigen-specificity, TCR clonotype and gene expression of single CD4+ T cells
Bjarke E. Hansen, ph.d. in Immunology – Immudex aps; Kivin Jacobsen, ph.d. – Immudex aps; Amir Ameri, M.sc. – Immudex aps; Liselotte Brix, ph.d. – Immudex aps
Tuesday, Jun 18
6:15 pm

T. 46 - Monitoring of antigen-specific, stimulation-induced mediator secretion, in clinical trials of infection, transplantaion, and immuno oncology using PepSup(TM) peptide pool strategy
Aaron Castro, PhD – JPT Peptide Technologies; Pavlo Holenya, PhD – JPT Peptide Technologies, GmbH; Maren Eckey, PhD – JPT Peptide Technologies, GmbH; Anja Teck – JPT Peptide Technologies, GmbH; Reimer Ulf, PhD – JPT Peptide Technologies, GmbH; Holger Wenschuh, PhD – JPT Peptide Technologies GmbH; Florian Kern, PhD – JPT Peptide Technologies, GmbH
Tuesday, Jun 18
6:15 pm

T. 48 - Revisiting the initial diagnosis and blood staging of Mycosis Fungoides and Sézary Syndrome with the KIR3DL2 marker
Marie Rolens – INSERM 1160; Adèle de Masson – Dermatology department; Caroline Ram-Wolff – Dermatology department; Anne Marie-Cardine – INSERM 976; Armand Bensussan – INSERM 976; Antoine Toubert – INSERM 1160; Martine Bagot – Dermatology department; Hélène Moins-Teisserenc – INSERM 1160
Tuesday, Jun 18
6:15 pm

T. 49 - TCRB Convergence in Peripheral Blood: Studies in Chronic Viral Infection and Cancer
Geoffrey M. Lowman – Thermo Fisher Scientific; Tim Looney – Thermo Fisher Scientific; Alice Zheng – Thermo Fisher Scientific; Janice Au-Young – Thermo Fisher Scientific
Tuesday, Jun 18
6:15 pm

T. 50 - Th17-derived Cytokines Might be Involved in the Allergic Contact Dermatitis Induced by Poison Ivy Active Ingredient, Urushiol.
Harun Rashid, PhD – Charles River; Richard Graveline, PhD – Charles River; Morad Haida, MSc – Charles River; Marie-Soleil Piche, PhD – Charles River; Michael Nivens, phD – Regeneron; David Hayes, PhD – AstraZeneca; Rana Samadfam, MSc, PhD, DABT – Charles River
Tuesday, Jun 18
6:15 pm

T. 51 - Validation of a Gliadin α-I/α-II DQ2 Tetramer Flow Cytometric Assay for use as a Biomarker to Assess Gluten Specific T cells in Celiac Disease
Will McAuliffe – Takeda Pharmaceuticals; Lynn Kisselbach – Precision for Medicine; Angelina Bisconte – Precision for Medicine; William Kwok, PhD – Benaroya Research Institute; Deborah Phippard, PhD – Precision for Medicine; Jose Estevam – Takeda Pharmaceuticals; Glennda Smithson, PhD – Takeda Pharmaceuticals
Tuesday, Jun 18
6:15 pm

T. 52 - Age related declined immunity and inflammation as reflected by the CD4 T-cell landscape
Yehezqel Elyahu – Ben Gurion University of the Negev; Idan Hekselman – Ben-Gurion University of the Negev; Inbal Eizenberg-Magar – Weizmann Institute of Science; Omer Berner – Ben-Gurion University of the Negev; Itai Strominger – Ben-Gurion University of the Negev; Maya Schiller – Technion - Israel Institute of Technology; Kritika Mittal – Ben-Gurion University of the Negev; Anna Nemirovsky – Ben-Gurion University of the Negev; Ekaterina Eremenko – Ben-Gurion University of the Negev; Vered Chalifa-Caspi – Ben-Gurion University of the Negev; Nir Friedman – Weizmann Institute of Science; Esti Yeger- Lotem – Ben-Gurion University of the Negev; Alon Monsonego – Ben-Gurion University of the Negev
Tuesday, Jun 18
6:15 pm

T. 53 - An open-source web-based analytics platform for the human immune atlas
Martin Wasser, PhD, MTech-KE – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre; Joo Guan Yeo, PhD, MBBS, MMed (Paediatrics), MRCPCh (UK) – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Kumar Pavanish – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Thaschawee Arkachaisri, MD, FACR – KK Women’s and Children’s Hospital; Su Li Poh – Translational Immunology Institute/SingHealth Duke-NUS Academic Medical Centre; Fauziah Ally – Translational Immunology Institute/ SingHealth Duke-NUS Academic Medical Centre; Jing Yao Leong, PhD – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Kee Thai Yeo, MD CM (McGill U, Canada), Diplomate of the American Board of Pediatrics (General Pediatrics, Neonatal-Perinatal Medicine, Pediatric Infectious Diseases) – Translational Immunology Institute/ SingHealth Duke-NUS Academic Medical Centre; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre
Tuesday, Jun 18
6:15 pm

T. 54 - Salt modulates cellular metabolism of regulatory T cells
Beatriz Côrte-Real – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium; Ibrahim Hamad – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium; Anneleen Geuzens – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium; Ludwig Dubois – Department of Radiation Oncology (Maastro), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, The Netherlands; Markus Kleinewietfeld – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium
Tuesday, Jun 18
6:15 pm

T. 55 - Single cell RNAseq data analysis using an extendable shiny app
Bernd Jagla – Pasteur Institut; Valentina Libri – Pasteur Institut; Vincent Rouilly – Datactix SASU; Thomas Cokelaer – Pasteur Institut; Milena Hasan – Pasteur Institut
Tuesday, Jun 18
6:15 pm

T. 56 - Crossreactive influenza A T-cell Receptor Repertoire Diversity and Selection in Acute through Persistent Epstein-Barr Virus (EBV) Infection
Anna Gil, Ph.D. – University of Massachusetts Medical School; Ramakanth Chirravuri, B.S. – University of Nebraska Omaha; Larisa Kamga – University of Massachusetts Medical School; Dario Ghersi, MD, PhD – University of Nebraska; Katherine Luzuriaga, MD – University of Massachusetts Medical School; Liisa K. Selin, MD, PhD – University of Massachusetts Medical School
Tuesday, Jun 18
6:15 pm

T. 57 - Cross-reactivity between influenza A and Epstein Barr Virus CD8 T cell responses influences TCRVβ repertoire evolution with age
Fransenio Clark, B.S. – University of Massachusetts Medical School; Rabinarayan Mishra, Ph.D. – University of Massachusetts Medical School; Anna Gil, Ph.D. – University of Massachusetts Medical School; Nuray Aslan, Ph.D. – University of Massachusetts; Katherine Luzuriaga, MD – University of Massachusetts Medical School; Liisa K. Selin, MD, PhD – University of Massachusetts Medical School
Tuesday, Jun 18
6:15 pm

T. 58 - Dramatically decreased and delayed CD8 T cell responses during asymptomatic EBV seroconversion
Liisa K. Selin, MD, PhD – University of Massachusetts Medical School; Fransenio Clark, B.S. – University of Massachusetts Medical School; Rabinarayan Mishra, Ph.D. – University of Massachusetts Medical School; Anna Gil, Ph.D. – University of Massachusetts Medical School; Ramakanth Chirravuri, B.S. – University of Nebraska Omaha; Dario Ghersi, MD, PhD – University of Nebraska; Katherine Luzuriaga, MD – University of Massachusetts Medical School
Tuesday, Jun 18
6:15 pm

T. 59 - Epitope selection for DQ2 presentation: implications for celiac disease and viral defense
Shu-Chen Hung, PhD – Stanford University; Tieying Hou – MD Anderson Cancer Center; Wei Jiang, PhD – Stanford University; Nan Wang – Stanford University; Shuo-Wang Qiao, MD PhD – University of Oslo and Oslo University Hospital- Rikshospitalet; I-Ting Chow, PhD – Benaroya Research Institute; Xiaodan Liu – Stanford University; Sjoerd van der Burg, PhD – Leiden University Medical Center; David Koelle, MD – University of Washington; William Kwok, PhD – Benaroya Research Institute; Ludvig Sollid, PhD – University of Oslo and Oslo University Hospital- Rikshospitalet; Elizabeth Mellins, MD PhD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Tuesday, Jun 18
6:15 pm

T. 61 - Generation of functional human T-cells in NOD/SCID/IL2rγnull (NSG) humanized mice without the use of fetal tissue
Chloe Colas – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Olga Volodina – Montreal Clinical Research Institute; Yuanyi Li – CHU Sainte Justine Research Center; Tram N.Q. Pham – Montreal Clinical Research Institute; William Lemieux – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Aurélien Colamartino – CHU Sainte-Justine Research Center, Department of Microbiology and Immunology, University of Montreal; Frédéric Dallaire – Montreal Clinical Research Institute; Camille Tremblay-Laganière – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Renee Dicaire – CHU Sainte-Justine; Jean Guimond – CLSC des Faubourgs, CIUSSS du Centre-Sud-de-l’Ile-de-Montréal; Natasha Patey – CHU Sainte-Justine, Department of Pathology; Suzanne Vobecky – CHU Sainte-Justine/University of Montreal, Department of Surgery; Nancy Poirier – CHU Sainte-Justine/University of Montreal, Department of Surgery; Eric Cohen, FCAHS, FRSC – Montreal Clinical Research Institute; Elie Haddad – CHU Sainte-Justine Research Center, Department of Microbiology, Infectiology and Immunology, University of Montreal; Department of Pediatrics, University of Montreal
Tuesday, Jun 18
6:15 pm

T. 62 - High Interleukin-7 serum concentrations in chronic infectious lung diseases as biomarkers of T-cell dysfunction
Christian Lundtoft – Childrens University Hospital; Julia Seyfarth – Childrens University Hospital; Marc Jacobsen – Children University Hospital Duesseldorf
Tuesday, Jun 18
6:15 pm

T. 63 - High levels of CD38 expression in SLE CD8 T cells dictate decreased cytotoxicity
Eri Katsuyama, MD,PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Abel Suarez-Fueyo, PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Sean Bradly, PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Lama Mulki, MD, PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Vasileios Kyttaris, MD, PhD – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; George Tsokos, MD. – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 64 - HVEM Signaling Promotes Protective Antibody-Dependent Cellular Cytotoxicity (ADCC) Vaccine Responses to Herpes Simplex Viruses (HSV)
Clare N. Burn, M.S – Albert Einstein College of Medicine; Lip Nam Loh, PhD – Albert Einstein College of Medicine; Carl F. Ware, PhD – Sanford Burnham Prebys Medical Discovery Institute; Benjamin Galen, MD – Albert Einstein College of Medicine; William R. Jacobs, Jr., PhD – Albert Einstein College of Medicine; Betsy C. Herold, MD – Albert Einstein College of Medicine
Tuesday, Jun 18
6:15 pm

T. 65 - Identification of a common transcriptional signature for regulatory B cells in Humans and Mice
Florian Dubois – Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, université de Nantes, Nantes; Sophie Limou – CRTI UMR1064, INSERM, Université de Nantes; Mélanie Chesneau – CRTI UMR1064, INSERM, Université de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Richard Danger – CRTI UMR1064, INSERM, Université de Nantes
Tuesday, Jun 18
6:15 pm

T. 66 - Identification of a Novel NK Cell Immune Evasion Strategy Based on a Secreted Viral CD48 Decoy Receptor
Ana Angulo – Universidad de Barcelona; Pablo Martínez-Vicente – University of Barcelona; Domenec Farré – University of Barcelona; Carolina Sánchez – Centro de Biología Molecular Severo Ochoa; Antonio Alcamí – Centro de Biología Molecular Severo Ochoa; Pablo Engel – University of Barcelona
Tuesday, Jun 18
6:15 pm

T. 67 - IL-1 and IL-33 differentially regulate the functional specialization of mucosal Foxp3+ regulatory T cells
Fernando Alvarez, DVM – McGill University; Roman Istomine – McGill University; Nils Pavey – McGill University; Mitra Shourian, PhD – McGill University; Salman Qureshi, MD – McGill University; Jorg Fritz, PhD – McGill University; Ciriaco Piccirillo, Ph.D. – McGill University
Tuesday, Jun 18
6:15 pm

T. 68 - Isolation and Characterization of an HIV-1 Broadly Neutralizing Antibody From a Clade C Infected Pediatric Elite Neutralizer
Sanjeev Kumar, PhD Student – All India Institute of Medical Sciences; Harekrushna Panda, PhD – International center for genetic engineering and biotechnology, New Delhi, India; Muzamil Ashraf. Makhdoomi, PhD – All India Institute of Medical Sciences; Nitesh Mishra, PhD Student – All India Institute of Medical Sciences; Haaris Ahsan Safdari, PhD Student – Indian Institute of Science; Himanshi Chawla, Masters Student – All India Institute of Medical Sciences; Heena Aggarwal, PhD – All India Institute of Medical Sciences; Elluri Seetharami Reddy, PhD Student – ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology; Rakesh Lodha, Professor of Pediatrics – All India Institute of Medical Sciences; Sushil Kumar Kabra, Professor of Pediatrics – All India Institute of Medical Sciences; Anmol Chandele, PhD – International center for genetic engineering and biotechnology, New Delhi, India; Somnath Dutta, PhD – Indian Institute of Science; Kalpana Luthra, PhD – All India Institute of Medical Sciences
Tuesday, Jun 18
6:15 pm

T. 69 - Laboratory diagnosis and monitoring of treatment efficacy in Lyme disease using an IFNgamma release assay
Paul M. Arnaboldi, PhD – New York Medical College; Christina D'Arco – New York Medical College; Sheila Nolan, MD – New York Medical College; Yosefa Hefter, MD – New York Medical College; Aleksandra Stuparic-Stancic, MD – Gundersen Health System; Dean Jobe – Gundersen Health System; Steven Callister, PhD – Gundersen Health System; Raymond Dattwyler, MD – New York Medical College
Tuesday, Jun 18
6:15 pm

T. 70 - Long-Term Durability of Protective Memory in Recurrent Staphylococcus aureus Skin Infection
Liana C. Chan, PhD – Los Angeles Biomedical Research Institute; Scott G. Filler, MD – University of California, Los Angeles; Lloyd S. Miller, MD – Johns Hopkins; Hong K. Lee, MS – Los Angeles Biomedical Research Institute; Michael R. Yeaman, PhD – University of California, Los Angeles
Tuesday, Jun 18
6:15 pm

T. 71 - Micro-RNA 29 regulates age-related differences in the CD8+ T cell response
Kristel J. Yee Mon, BSc. – Cornell University; Norah Smith – Cornell University; Luyen Tien. Vu – City University of Hong Kong; Ciaran Daly – Cornell University; Andrew Grimson, PhD – Cornell University; Brian Rudd, PhD – Cornell University
Tuesday, Jun 18
6:15 pm

T. 72 - Modeling CD8+ T Cell Responses Against Liver Infection with 3D Organoids
Camille R. Simoneau – Gladstone Institutes/University of California, San Francisco; Vaishaali Natarajan, PhD – Gladstone Institutes; Ann Erickson – California Pacific Medical Center; Nathan Meyers, PhD – Gladstone Institutes; Jody L. Baron, MD, PhD – University of California, San Francisco; Stewart Cooper, MD – California Pacific Medical Center; Todd C. McDevitt, PhD – Gladstone Institutes; Melanie Ott, MD, PhD – Gladstone Institutes
Tuesday, Jun 18
6:15 pm

T. 73 - Phlebotomus papatasi Yellow-Related and Apyrase Salivary Proteins Are Candidates for Vaccination against Human Cutaneous Leishmaniasis
Tlili Aymen, Immunology – Pasteur Institute of Tunis
Tuesday, Jun 18
6:15 pm

T. 74 - Prevalence of Rotavirus and Levels of Immunoglobulin (IgA, IgG, IgM) in Children with Gastroenteritis in Nnewi, Anambra State, Nigeria.
Martin OSITADINMA. Ifeanyichukwu – NNAMDI AZIKIWE UNIVERSITY, COLLEGE OF HEALTH SCIENCES NNEWI CAMPUS, NNEWI; Kris A. Chinweokwu, BSc. MSc in view – IMMUNOLOGY DEPT, FACULTY OF MEDICINE, COLLEGE OF HEALTH SCIENCES, NNAMDI AZIKIWE UNIVERSITY, NNEWI,NIGERIA
Tuesday, Jun 18
6:15 pm

T. 75 - Pro-inflammatory cytokines as potential prognosis biomarkers in respiratory diseases caused by virus
Yaneisi Vazquez – Pontificia Universidad Catolica de Chile; Liliana A. Gonzalez – Pontificia Universidad Católica de Chile; Pablo Bertrand – Pontificia Universidad Catolica de Chile; Andrea Beckhaus – Pontificia Universidad Catolica de Chile; Carolina Iturriaga – Pontificia Universidad Catolica de Chile; Alexis M. Kalergis – Pontificia Universidad Católica de Chile; Susan M. Bueno – Pontificia Universidad Católica de Chile
Tuesday, Jun 18
6:15 pm

T. 76 - Reprogramming of Exhausted T Cells Following Cure of Chronic Viral Infection
Mohamed S. Abdel-Hakeem, PhD – Penn Institute for Immunology, University of Pennsylvania; Jean-Christophe Beltra, PhD – Penn Institute for Immunology, University of Pennsylvania; Zeyu Chen, MSc – University of Pennsylvania; Sasikanth Manne, MSc – Penn Institute for Immunology, University of Pennsylvania; E. John Wherry, PhD – Penn Institute for Immunology, University of Pennsylvania
Tuesday, Jun 18
6:15 pm

T. 77 - Role of Ly6G+ cells during Salmonella enterica serovar Typhimurium infection
Barbara M. Schultz – Pontificia Universidad Catolica de Chile; Fernanda Balmaceda – Pontificia Universidad Catolica de Chile; Valentina P. Sebastian – Pontificia Universidad Catolica de Chile; Susan M. Bueno – Pontificia Universidad Católica de Chile
Tuesday, Jun 18
6:15 pm

T. 78 - Scalable and comprehensive characterization of antigen-specific CD8 T cells using multi-omics single cell analysis
Josephine Y. Lee – 10x Genomics; Julia K. Lau – 10x Genomics; Stephane C. Boutet – 10x Genomics; Dagmar Walter – 10x Genomics; Michael J. T. Stubbington – 10x Genomics; Katherine A. Pfeiffer – 10x Genomics; Sarah E. B. Taylor – 10x Genomics; Jerald Sapida – 10x Genomics; Luz Montesclaros – 10x Genomics; Daniel P. Riordan – 10x Genomics; Alvaro Martinez Barrio – 10x Genomics; Liselotte Brix, ph.d. – Immudex aps; Kivin Jacobsen, ph.d. – Immudex aps; Bertrand Yeung – BioLegend; Xinfang Zhao – BioLegend; Tarjei S>. Mikkelsen – 10x Genomics
Tuesday, Jun 18
6:15 pm

T. 79 - Signaling via the TLR adaptor MyD88 produces transient immune unresponsiveness during infection of mice with pathogenic Salmonella
Mohd Anees Ahmed – National Institute of Immunology, New Delhi, India
Tuesday, Jun 18
6:15 pm

T. 80 - Temperospatial Evolution of Cellular Immune Memory During MRSA Infection
Liana C. Chan, PhD – Los Angeles Biomedical Research Institute; Maura Rossetti, PhD – University of California, Los Angeles; Scott G. Filler, MD – University of California, Los Angeles; Lloyd S. Miller, MD – Johns Hopkins; Hong K. Lee, MS – Los Angeles Biomedical Research Institute; Vance G. Fowler, Jr., MD – Duke University; Elaine F. Reed, PhD – University of California, Los Angeles; Michael R. Yeaman, PhD – University of California, Los Angeles
Tuesday, Jun 18
6:15 pm

T. 81 - Different Clinical Manifestations in A Large Cohort of Predominantly Antibody Deficiency Patients with Monogenic Defects
Reza Yazdani – Research Center for Immunodeficiencies; Hassan Abolhassani – Karolinska Institute at Karolinska University Hospital Huddinge; Asghar Aghamohammadi – Research Center for Immunodeficiencies
Tuesday, Jun 18
6:15 pm

T. 82 - Gene polymorphisms in IFNγ and TNFα genes associate with faster disease progression in HIV-1 Subtype-C infected individuals from North India
Sunil K. Arora – PGIMER, Chandigarh
Tuesday, Jun 18
6:15 pm

T. 83 - GM-CSF signalling pathway activates human GATA-2 transcription factor trough STAT5 phosphorylation.
Elie Haddad – CHU Sainte-Justine Research Center, Department of Microbiology, Infectiology and Immunology, University of Montreal; Department of Pediatrics, University of Montreal; Silvia Selleri, PhD – CHU Sainte-Justine Research Center, Montreal, QC, Canada; Department of Microbiology, Infectiology and Immunology, University of Montreal; Véronique Caron – CHU Sainte-Justine Research Center, Montreal, QC, Canada; Jonathan Gagnon – CHU Sainte-Justine Research Center, Montreal, QC, Canada; Department of Biochemistry and Molecular Medicine, University of Montreal; André Tremblay – CHU Sainte-Justine Research Center, Montreal, QC, Canada; Department of Biochemistry and Molecular Medicine, University of Montreal; Department of Obstetrics & Gynecology, University of Montreal
Tuesday, Jun 18
6:15 pm

T. 84 - Homozygosity for a novel CARD11 mutation causes profound combined immunodeficiency (CID), inflammatory gastrointestinal disease, and complete abrogation of MALT1 activity
Henry Lu, BSc – The University of British Columbia; Sneha Suresh, MD, FRCPC – University of Alberta and Alberta Health Services; Lyle McGonigle, MD, FRCPC – Alberta Health Services; Joanne Luider, BSc, ART, MLT – Calgary Laboratory Services; Stuart Turvey, MBBS, DPhil, FRCPC – BC Children's Hospital (UBC)
Tuesday, Jun 18
6:15 pm

T. 85 - Low Dose Azithromycin Prophilaxys Reduces Respiratory Exacerbations in Primary Antibody Ddeficiencies: a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial
Cinzia Milito – Sapienza University of Rome; Federica Pulvirenti – Sapienza University of Rome; Francesco Cinetto – Department of Medicine; Maria Carrabba – Department of Internal Medicine Milan; Giovanna Fabio – Department of Internal Medicine Milan; Rosa Maria Dellepiane – Department of Internal Medicine Milan; Carlo Agostini – Department of Medicine; Alessandro Plebani – 3Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia; Vassilios Lougaris – Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia; Anna Rosa Soresina – Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia; Andrea Matucci – Immunoallergology Unit, Department Medical-Geriatric, AOU Careggi; Alessandra Vultaggio – Immunoallergology Unit, Department Medical-Geriatric, AOU Careggi; Giuseppe Spadaro – Department of Translationenter for Basic and Clinical Immunology Research, University of Naples Federico II, Naples; Antonio Pecoraro – Department of Translational Menter for Basic and Clinical Immunology Research, University of Naples Federico II, Naples; Baldassarre Martire – Department of Biomedicine and Evolutive Age, University of Bari; Isabella Quinti – Sapienza University of Rome
Tuesday, Jun 18
6:15 pm

T. 86 - Men' immune system age faster and more severely than women'
Duygu Ucar, PhD – Jackson Laboratory
Tuesday, Jun 18
6:15 pm

T. 87 - Primary immunodeficiency with severe multi-organ immune dysregulation
Tatyana Gavrilova, MD – Montefiore Medical Center; Yoomie Lee, MD – National Jewish Health
Tuesday, Jun 18
6:15 pm

T. 89 - The adenosine salvage pathway is induced in late human transitional 3 B cells and facilitates their metabolic reprograming toward a mature follicular B cell fate
Hugues Allard-Chamard, MD PhD FRCPC – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA | Division of Rheumatology, FMSS, Sherbrooke, Québec, Canada.; Jocelyn R. Farmer, MD PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA |Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA; Na Sun, Bioinformatician – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Maimuna Ahmad – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Vinay S. Mahajan, MD PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Toby Aicher – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Johan Arnold, PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Mark D. Benson, MD – Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Jordan Morningstar – Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Sara Barmettler, MD PhD – Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, USA; Alice Bertocchi – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Grace Yuen, PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Sam Murphy – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Jolan E. Walter, MD PhD – Division of Rheumatology, Allergy and Immunology, MGH, Boston, Boston, MA | Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA | Johns Hopkins All Children’s Hospital, St. Petersburg, FL, USA; Alex K. Shalek, PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Facundo Batista, PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Robert Gerszten, MD – Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Shiv Pillai, MD PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA
Tuesday, Jun 18
6:15 pm

T. 90 - Application of the Anti-Inflammatory Ocular Neuropeptide Alpha-Melanocyte Stimulating Hormone (α-MSH) Suppresses Damage in Retinas with Ischemia/Reperfusion
Nayan Sanjiv, BA – Boston University School of Medicine; Tat Fong Ng, PhD – Boston University School of Medicine; Andreas Towers – Boston University School of Medicine; Amy C. Y. Lo, PhD – The University of Hong Kong; Andrew W. Taylor, PhD – Boston University School of Medicine
Tuesday, Jun 18
6:15 pm

T. 91 - Enhanced memory CD8 T cells with immunosenescent-like phenotype in uveitis patients
Vrushali Agashe, PhD – National Eye Institute/NIH; Benjamin Chaigne-Delalande, PhD – Nationla Eye Institute/NIH; Sima Hirani – National Eye Institute/NIH; Andrew Kalra – National Eye Institute/NIH; Angelique Biancotto – NIH; Julian Candia, PhD – CCR, NCI, NIH; Richard W.J. Lee, MD – University of Bristol/Moorfields Eye Hospital; H. Nida Sen, MD – National Eye Institute/NIH
Tuesday, Jun 18
6:15 pm

T. 92 - Prolonged antibiotic treatment reverses the protective effect of gut microbiota depletion on autoimmune disease
Ryan S. Salvador, PhD – Lab Immunol, NEI, NIH; Reiko Horai, PhD – Lab Immunol, NEI, NIH; Yingyos Jittayasothorn, PhD – Lab Immunol, NEI, NIH; Jihong Tang, BSc – Lab Immunol, NEI, NIH; Colm OHuigin, PhD – Genetics and Microbiome Core, NCI, NIH; Vishal Thovarai, PhD – Genetics and Microbiome Core, NCI, NIH; Wuxing Yuan, PhD – Genetics and Microbiome Core, NCI, NIH; Yuen Amy Zhang, PhD – Lab Immunol, NEI, NIH; Rachel R. Caspi, PhD – Lab Immunol, NEI, NIH
Tuesday, Jun 18
6:15 pm

T. 93 - Retinal Pigment Epithelial cells do not suppress the phagocytic antigen processing pathways in antigen presenting cells during Experimental Autoimmune Uveitis
Tat Fong Ng, PhD – Boston University School of Medicine; Isaac J. Benque, BA – Ophthalmology, Boston University School of Medicine; Brandon Lee – Ophthalmology, Boston University School of Medicine; John Muus, BSc – Medical University of South Carolina; Andrew W. Taylor, PhD – Boston University School of Medicine
Tuesday, Jun 18
6:15 pm

T. 94 - Single-cell RNA sequencing coupled with T-cell-receptor (TCR) sequencing provides unprecedented insight into granulomatous uveitis.
Lynn M. Hassman, MD. PhD – Washington University in St. Louis; Michael M. Paley, MD, PhD – Washington University in St. Louis; Ekaterina M. Esaulova, BS – Washington University in St. Louis; Wayne Yokoyama, MD, PhD – Washington University in St. Louis
Tuesday, Jun 18
6:15 pm

T. 95 - A C-terminal fragment of adhesion protein Fibulin7 (Fbln7C) inhibits tumor growth via targeting both cancer cells and tumor associated macrophages.
Papiya Chakraborty, MSc – Indian Institute of Technology Roorkee; Yoshihiko Yamada, PhD – National Institutes of Health; Pranita P. Sarangi, DVM PhD – Indian Institute of Technology Roorkee
Tuesday, Jun 18
6:15 pm

T. 96 - A New Conditioned Tumor Lysate Based Melanoma Vaccine Inhibits Tumor Growth and Potentiates anti PD1 Treatment
Flavio Salazar-Onfray – Universidad de CHILE
Tuesday, Jun 18
6:15 pm

T. 97 - A Translational Platform to Support and Advance Immuno-Oncology Drug Discovery
Shilina Roman – Charles River; Gary Salmon – Charles River; Julie Hawkins – Charles River; Jonathan White – Charles River; Ria Goodwin – Charles River; Runi Ganguli – Charles River; Omar Aziz – Charles River; Julia Schueler – Charles River; Edgar Wood, PhD – Charles River; Jeroen DeGroot, PhD – Charles River Laboratories; Ian Waddell – Charles River
Tuesday, Jun 18
6:15 pm

T. 98 - An antigen-specific memory stem T cell (TSCM) expansion system for adoptive T cell immunotherapy
Tino Vollmer – Institute for Medical Immunology, Charité University Medicine Berlin; Leila Amini – Charité Universitaetsmedizin Berlin; Petra Reinke – Charité Universitaetsmedizin Berlin; Hans-Dieter Volk, M.D./Ph.D. – Charité Universitaetsmedizin Berlin; Michael Schmueck-Henneresse, Ph.D. – Charité Universitaetsmedizin Berlin
Tuesday, Jun 18
6:15 pm

T. 99 - Analysis of molecular and cellular responses associated with immune checkpoint inhibition in the MC38 colon carcinoma model
Patrick Fadden, PhD – Charles River Laboratories; Thi Bui, PhD – Charles River Laboratories; Kelli Davis, BS – Charles River Laboratories; Ian Belle, PhD – Charles River Laboratories; David Hurtado, PhD – Charles River Laboratories; Cristina Sokolowski, BS – Charles River Laboratories; Kathrine Krontz, MS – Charles River Laboratories; Jacob Hauser, BS – Charles River Laboratories; Na Li, PhD – Charles River Laboratories; Kyle Takayama, PhD – Charles River Laboratories; David Harris, PhD – Charles River Labaoratories; Edgar Wood, PhD – Charles River
Tuesday, Jun 18
6:15 pm

T. 100 - Antagonism of the TNF Superfamily of Receptors: Focus on Novel Functional Antibodies with Preference for the Tumor Microenvironment
Heather L. Torrey, PhD – Massachusetts General Hospital/Harvard Medical School; Lisa Tran, BS – Massachusetts General Hospital/Harvard Medical School; Michael Yang, BS – Massachusetts General Hospital/Harvard Medical School; Eva Vanamee, PhD – Massachusetts General Hospital/Harvard Medical School; Denise L. Faustman, MD, PhD – Massachusetts General Hospital/Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 101 - Application of a novel dimer-avoided multiplex PCR technique in immune repertoire profiling for renal cancer treatment evaluation
Wenjing Pan – iRepertoire Inc.; Mollye Depinet – iRepertoire, inc.; Shang-Gin Wu – Department of Internal Medicine, National Taiwan University Cancer Center, National Taiwan University; Xiaohong Hou – iRepertoire, Inc.; Brittany Brown – iRepertoire, Inc.; Mary Eisenhower – iRepertoire, Inc.; Alexa Fort – iRepertoire, Inc.; Song Li – iRepertoire, Inc.; Miranda Byrne-Steele – iRepertoire, Inc.; Michael Lotze – UPMC Hillman Cancer Center; Jian Han – iRepertoire, Inc.
Tuesday, Jun 18
6:15 pm

T. 102 - Association of Tumor-Associated Immune Cell Markers With Tumor Size And Lymph Node Metastasis in Oral Squamous Cell Carcinoma-Gingivo-Buccal (SCC-GB) : A Retrospective Study on Formalin Fixed Paraffin Embedded (FFPE) Tissue
Geetashree Mukherjee – Tata Medical Center, Kolkata, India; Prasenjit Chakraborty – Tata Medical Center, Kolkata, India; Swarnendu Bag – Tata Medical Center, Kolkata, India; Suparna Dutt – Stanford University School of Medicine, Stanford, CA 94305-5166, USA; Partha P Majumder – National Institute of Biomedical Genomics, Kalyani, India
Tuesday, Jun 18
6:15 pm

T. 103 - Attenuated Listeria Vaccine for Cancer Immunotherapy Expands Vγ2Vδ2 T Cells in Rhesus Monkeys that Retain their Central Memory Phenotype and HMBPP Responsiveness
Craig T. Morita, M.D., Ph.D. – University of Iowa/VA Health Care System; Mohanad H. Nada, Ph.D. – American University of Iraq, Sulaimani; Grefachew Workalemahu, Ph.D. – University of Iowa College of Medicine; Hong Wang, M.D., Ph.D. – University of Iowa College of Medicine
Tuesday, Jun 18
6:15 pm

T. 104 - Building a Translational Pathway Using Human Myeloid Cell Assays to Enable Development of Cancer Immune Therapies
Rhiannon Jenkinson, PhD – Charles River Portishead; Robert Nunan, PhD – Charles River Portishead; Louise S. Brackenbury, PhD – Charles River Laboratories
Tuesday, Jun 18
6:15 pm

T. 105 - Building a Translational Pathway Using Pharmacodynamic Models to Enable the Development of Cancer Immune Therapies
Rhiannon Jenkinson, PhD – Charles River Portishead; Anna Willox, PhD – Charles River Portishead; Robert Nunan, PhD – Charles River Portishead; Clio Andreae, PhD – Charles River Portishead; Louise S. Brackenbury, PhD – Charles River Laboratories; Tommaso Iannitti, PhD – Charles River Laboratories; Neil A. Williams, PhD – Charles River Laboratories
Tuesday, Jun 18
6:15 pm

T. 106 - CD45 activity modulation as a novel therapeutic target in B-cell malignancies
Julia Heinzelbecker, MSc – University of Oslo; Britt Nakken, PhD – University of Oslo; Peter Szodoray, MD, PhD – Oslo University Hospital; Ludvig A. Munthe, MD, PhD – University of Oslo; John F. Imbery, PhD – University of Oslo; Camilla Myklebust, MSc – University of Oslo; Anders Tveita, MD, PhD – University of Oslo; Geir Tjonnfjord, MD, PhD – University of Oslo; Stephanie Stanford, PhD – UCSD; Nunzio Bottini, PhD – UCSD; Fredrik Schjesvold, MD, PhD – University of Oslo
Tuesday, Jun 18
6:15 pm

T. 107 - Characterisation of Activated T-Cells and Virus Specific T-Cells as a Platform for Chimeric Antigen Receptor Therapy
Richard Hopkins – Tessa Therapeutics; Yovita Purwanti – Tessa Therapeutics; Tan Tong Wei – Tessa Therapeutics; Ying Ying Kong – Tessa Therapeutics; Novita Novita – Tessa Therapeutics; Enjun Yang – Tessa Therapeutics; John Connolly – Tessa Therapeutics
Tuesday, Jun 18
6:15 pm

T. 108 - Characterization of the immunogenic determinants of tumor neoantigens improves their identification
Aude-helene Capietto – Genentech; Suchit Jhunjhunwala – Genentech; Patrick Lupardus – Genentech; Jim Wong – Genentech; Lena Hansch – Genentech; James Cevallos – Genentech; Yajun Chestnut – Genentech; Ajay Fernandez – Genentech; Tamaki Nozawa – Genentech; Manmeet Singh – Genentech; Cecile De la Cruz – Genentech; Benjamin Haley – Genentech; Joshua Gober – Genentech; Adel ElSohly – Genentech; Jonathan Linehan – Genentech; Ira Mellman – Genentech; Richard Bourgon – Genentech; Lelia Delamarre – Genentech
Tuesday, Jun 18
6:15 pm

T. 109 - Deciphering the role of the tumor infiltrating lymphocytes in anti-angiogenic therapy using a humanized PDX in vivo platform
Julia Schueler – Charles River; Nathalie Harrer – Boehringer Ingelheim RCV GmbH & Co KG; Anna Edinger – Charles River Research Services Germany GmbH; Cordula Tschuch – Charles River Research Services Germany GmbH; Eva Oswald – Charles River Research Services Germany GmbH; Wolfgang Sommergruber – Boehringer Ingelheim RCV GmbH & Co KG
Tuesday, Jun 18
6:15 pm

T. 111 - Evaluation of TNFR2 Antagonism with and without Anti-PD-1 Therapy in Murine Colon Cancer Models
Katie Case, BS – Massachusetts General Hospital/Harvard Medical School; Lisa Tran, BS – Massachusetts General Hospital/Harvard Medical School; Denise L. Faustman, MD, PhD – Massachusetts General Hospital/Harvard Medical School
Tuesday, Jun 18
6:15 pm

T. 112 - FIGHTING HIGH-RISK ACUTE LEUKEMIA: 𝛄ẟ T CELLS AS AN IMMUNOTHERAPY
Giulia Barbarito – Stanford school of medicine; Rachana Patil – Stanford School of Medicine; Patricia Maria Bergamo Favaro, PHD – Stanford School of medicine; Roshani Sinha, PHD – Stanford School of Medicine; Alessia Zorzoli – Gaslini Hospital; C.A Klein – Stanford School of Medicine; Irma Airoldi – Gaslini Hospital; Alice Bertaina, MD – Stanford University
Tuesday, Jun 18
6:15 pm

T. 113 - High salt blocks tumor growth by enhancing anti-tumor immunity
Ralf Willebrand – VIB; Ibrahim Hamad – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium; Beatriz Côrte-Real – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium; Lauren Van Zeebroeck – VIB; Mate Kiss – VIB; Thomas Kammertöns – MDC; Sven Brandau – UK Essen; Jo Van Ginderachter – VIB; Markus Kleinewietfeld – VIB Laboratory for Translational Immunomodulation, VIB Center for Inflammation Research (IRC), Hasselt University, Belgium
Tuesday, Jun 18
6:15 pm

T. 114 - β-catenin/TCF-1 signaling in Treg contributes to colon cancer
Abu Osman – Mayo Clinic; Abdulrahman Saadalla – Mayo Clinic; Fotini Gounari – The University of Chicago; Kevin Pavelko – Mayo Clinic; Khashayarsha Khazaie – Mayo Clinic
Tuesday, Jun 18
6:15 pm

T. 115 - Long term time-course monitoring of NK cell-mediated ADCC using the Celigo Image Cytometer
Leo L. Chan – Nexcelom Bioscience LLC; Lucas Ferrari De Andrade – Cancer Immunology and Virology; Charles Thomas – Dana Farber Cancer Institute; Dmitry Kuksin – Technology R&D; Kai Wucherpfennig – Cancer Immunology and Virology
Tuesday, Jun 18
6:15 pm

T. 116 - Building a Roadmap of Early Human Immune System Development Through Single Cell and Bulk RNA Sequencing
Daniel Bunis – University of California, San Francisco; Rachel L. Rutishauser, MD – University of California, San Francisco; Ventura Mendoza – University of California, San Francisco; Chun Jimmie Ye, PhD – University of California, San Francisco; Trevor D. Burt, MD – University of California, San Francisco
Tuesday, Jun 18
6:15 pm

T. 117 - Clinical Immunones Dashboard for Electronic Health Records (CIDEHR): Securely Visualizing and Analyzing Flow Cytometry Data from Electronic Health Records
Thomas A. Peterson, PhD – UCSF Bakar Computational Health Sciences Institute; Benjamin Glicksberg, PhD – UCSF Bakar Computational Health Sciences Institute; Zicheng Hu, PhD – UCSF Bakar Computational Health Sciences Institute; Sanchita Bhattacharya, PhD – UCSF Bakar Computational Health Sciences Institute; Atul J. Butte, MD, PhD – UCSF Bakar Computational Health Sciences Institute
Tuesday, Jun 18
6:15 pm

T. 118 - Comparison of two different recombinant mycobacterial vaccine strains for HIV-TB coinfection
Shakila Harshavardhan, State Government University – Madurai Kamaraj University; Vignesh S – Madurai Kamaraj University; Sam Ebenezer Raja – Madurai Kamaraj University
Tuesday, Jun 18
6:15 pm

T. 119 - Immunogenicity of Peptide Drugs and their Impurities: A Case Study of Taspoglutide and its Impurities
Brian J. Roberts, PhD – Epivax, Inc.; Aimee Mattei, MS – Epivax, Inc.; Pooja Hindocha, BA – Epivax, Inc.; Frances Terry, MPH – Epivax, Inc.; William Martin – EpiVax; Annie DeGroot, M.D. – EpiVax
Tuesday, Jun 18
6:15 pm

T. 121 - Chimeric Antigen Receptor-mediated Control of Human Regulatory T Cell Function
Leonardo Ferreira, PhD – UCSF; Anupurna Kaul, PhD – UCSF; Yannick Muller, MD, PhD – UCSF; Ryan Guerrero-Moreno, B.S. – UCSF; Hashim Shaikh, B.S. – UCSF; Daniel Goodman, PhD – UCSF; Jeffrey Bluestone, PhD – UCSF; Qizhi Tang, Ph.D. – University of California San Francisco
Tuesday, Jun 18
6:15 pm

T. 122 - Comparison of C57Bl/6, NSG-PBMC, CD34-NSG, and SGM3 mice models for immune checkpoint receptor studies
Yang Zhao, PhD – Eli Lilly; Wei Zeng – Eli Lilly; Xiaohua Wu – Eli Lilly; Baker E. Hana, PhD – Eli Lilly
Tuesday, Jun 18
6:15 pm

T. 123 - Discovery and Characterization of PD-1 Agonist Antibodies
Lindsay Edwards – Pandion Therapeutics; Daniel Rios – Pandion Therapeutics; Salvatore Alioto – Pandion Therapeutics; Bridget Larkin – Pandion Therapeutics; Timothy Kiprono – Pandion Therapeutics; Nathan Higginson-Scott – Pandion Therapeutics; Joanne L. Viney – Pandion Therapeutics; Kevin L. Otipoby – Pandion Therapeutics
Tuesday, Jun 18
6:15 pm

T. 124 - Effects of Toll-Like Receptor 4 Protein Expression and Trait Anxiety on Adolescent Mesocorticolimbic Neuroplasticity in Amphetamine-Induced Locomotor Sensitization.
Corey A. Calhoun, B.A. – University of Massachusetts, Boston; Brooke Plotkin, B.A. – University of Massachusetts, Boston; Latifa Pina, B.S. – University of Massachusetts, Boston; Antonio Alves, B.S. – University of Massachusetts, Boston; S. Tiffany Donaldson, Ph.D. – University of Massachusetts, Boston
Tuesday, Jun 18
6:15 pm

T. 125 - Engineered FVIII specific murine CAR Tregs with optimized signal strength demonstrate enhanced in vivo efficacy
Moanaro Biswas, Ph.D – Indiana University School of Medicine; Sandeep Kumar, Ph.D – Indiana University School of Medicine; Daniel Perry, Ph.D – University of Florida; Rania Saboungi, BS – University of Florida; Todd M. Brusko, Ph.D. – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Roland W. Herzog, Ph.D – Indiana University School of Medicine
Tuesday, Jun 18
6:15 pm

T. 126 - Essential Role for the RHO-KINASES in Intestinal Stem Cell Viabilty and Maintenance of Organ Homeostasis
Rajita Pappu, PhD – GENENTECH
Tuesday, Jun 18
6:15 pm

T. 127 - Immunogenicity and Vaccine Potential of Tag-free Recombinant BmHAXT against Brugia malayi Parasite in a Mouse Model
Divya Sree Nagalati Sudhakar, Graduate – University of Illinois College of Medicine at Rockford; Vishal Khatri, PhD – University of Illinois College of Medicine at Rockford; Nikhil Chauhan, PhD – University of Illinois College of Medicine at Rockford; Ramaswamy Kalyanasundaram, DVM, PhD – University of Illinois College of Medicine Rockford-Department of Biomedical Sciences
Tuesday, Jun 18
6:15 pm

T. 128 - MAP7 and MUCL1 are Biomarkers of Vitamin D3-Induced Tolerogenic Dendritic Cells in Multiple Sclerosis Patients
Juan Navarro-Barriuso, MSc – Germans Trias i Pujol Research Institute; María José Mansilla, PhD – Germans Trias i Pujol Research Institute; Bibiana Quirant-Sánchez, MSc – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Alicia Ardiaca-Martínez, MSc – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Aina Teniente-Serra, PhD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Silvia Presas-Rodríguez, MD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona; Anja ten Brinke, PhD – Sanquin Research and University of Amsterdam; Cristina Ramo-Tello, MD, PhD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona; Eva M. Martínez-Cáceres, MD, PhD – Germans Trias i Pujol Research Institute
Tuesday, Jun 18
6:15 pm

T. 129 - Promising multifunctional peptide isolated from the Mexican tree frog Pachymedusa dacnicolor in the treatment of psoriasis
Veronica Martinez Osorio, BsC – Universidad Nacional Autonoma de México; Elizabeth Fajardo-Brigido, BsC – Universidad Nacional Autonoma de México; Estefania Aleman, MsC – Universidad Nacional Autonoma de México; Christophe Piesse, PhD – Sorbonne Université; Sandra Rodriguez, PhD – Escuela Nacional de Ciencias Biologicas; Christophe Combadière, PhD – Sorbonne Université; Claire Lacombe, PhD – Sorbonne Université; Yvonne Rosenstein, PhD – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Constance Auvynet, PhD – Universidad Nacional Autonoma de México
Tuesday, Jun 18
6:15 pm

T. 130 - Role for CD45 Phosphatase in Multiple Myeloma Plasma Cell Proliferation and Survival
John F. Imbery, PhD – University of Oslo; Julia Heinzelbecker, MSc – University of Oslo; Camilla Myklebust, MSc – University of Oslo; Nunzio Bottini, PhD – UCSD; Stephanie Stanford, PhD – UCSD; Ludvig A. Munthe, MD, PhD – University of Oslo; Anders Tveita, MD, PhD – University of Oslo; Fredrik Schjesvold, MD, PhD – University of Oslo; Geir Tjonnfjord, MD, PhD – University of Oslo; Peter Szodoray, MD, PhD – University of Oslo; Britt Nakken, PhD – University of Oslo
Tuesday, Jun 18
6:15 pm

T. 131 - Selective Expansion of Regulatory T cells by IL-2 Muteins
Erik R. Sampson – Pandion Therapeutics; Jyothsna Visweswaraiah – Pandion Therapeutics; Nathan Higginson-Scott – Pandion Therapeutics; Joanne L. Viney – Pandion Therapeutics; Kevin L. Otipoby – Pandion Therapeutics
Tuesday, Jun 18
6:15 pm

T. 132 - Targeting the Epichaperome as an Effective Precision Medicine Approach in a Novel PML-SYK Fusion Acute Myeloid Leukemia
Mayumi Sugita, MD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine; Juan Miguel Mosquera, MD MSc – Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine; David C Wilkes, PhD – Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine; Sarah Nataraj, PhD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine; Reyna A Jimenez-Flores, PhD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine; Rohan Bareja – Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine; LunBiao Yan, MD PhD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine; David Rickman, PhD – Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine; Wayne Tam, MD PhD – Department of Pathology and Laboratory Medicine, Well Cornell Medicine; Mark A. Rubin, MD – Department of Pathology and Laboratory Medicine, Well Cornell Medicine; Koen Van Besien, MD PhD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital; Bob Morgan – Samus Therapeutics, Inc; Duane C. Hassane, PhD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine; Olivier Elemento, PhD – Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine; Gabriela Chiosis, PhD – Memorial Sloan Kettering Cancer Center; Gail J. Roboz, MD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital; Monica L. Guzman, PhD – Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine
Tuesday, Jun 18
6:15 pm

T. 133 - Two in vitro assays for evaluating the potency and efficacy of prospective drugs in multiple diseases involving both classically and alternative activated macrophages
Krista Ouwehand, PhD – Charles River Laboratories; Sanne Laura. Demandt – Charles River Laboratories; Britt Sotthewes – Charles River Laboratories; Kimberly Lo – Charles River Laboratories; Linda van Diemen – Charles River Laboratories; Jeroen DeGroot, PhD – Charles River Laboratories; Jamil Aarbiou, PhD – Charles River Laboratories
Wednesday, Jun 19
6:15 pm

W. 7 - Follicular Regulatory T Cells Promote the Germinal Center Reaction and IgE Response in a Peanut Food Allergy Model
Markus Xie – Indiana University School of Medicine; Alexander Dent – Indiana University School of Medicine
Wednesday, Jun 19
6:15 pm

W. 12 - Airway Dendritic Cells Distinguish Allergic Asthmatics from Allergic Controls
Jehan Alladina, MD – Massachusetts General Hospital; Daniel Hamilos, MD – Massachusetts General Hospital; Andrew Luster, MD, PhD – Center for Immunology and Inflammatory Disease; Benjamin Medoff, MD – Massachusetts General Hospital; Josalyn Cho, MD – University of Iowa
Wednesday, Jun 19
6:15 pm

W. 50 - Ex vivo Generated Lymphoid Progenitors for Immune Reconstitution in the Context of Allogeneic Transplantation and Gene Therapy
Isabelle André – INSERM; Ranjita Moirangthem – INSERM; Kuiying Ma – INSERM; Juliette Olivre – Institut Imagine; Anne Cordesse – INSERM; Corinne de Chappedelaine – INSERM; Sabrina Lizot – INSERM; Chantal Lagresle-Peyrou – INSERM; Tayebeh-Shabi Soheili – INSERM; Marina Cavazzana – INSERM
Wednesday, Jun 19
6:15 pm

W. 61 - Exhaustion of Autoreactive CD8+ T Cells Distinguishes Slow Progression of Type 1 Diabetes
Alice Wiedeman, PhD – Benaroya Research Institute; Virginia Muir, Ph.D. – Benaroya Research Institute at Virginia Mason; Mario Rosasco, PhD – Benaroya Research Institute; Hannah DeBerg, PhD – Benaroya Research Institute; Scott Presnell, PhD – Benaroya Research Institute; Bertrand Haas, PhD – Benaroya Research Institute; Matthew Dufort, PhD – Benaroya Research Institute; Cate Speake, PhD – Benaroya Research Institute; Carla Greenbaum, MD – Benaroya Research Institute; Elisavet Serti, PhD – Immune Tolerance Network; Gerald Nepom, PhD – Immune Tolerance Network; Gabriele Blahnik, MS – Benaroya Research Institute; Anna Kus, BS – Benaroya Research Institute; Eddie James, Ph.D. – Benaroya Research Institute at Virginia Mason; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; S. Alice Long, PhD – Benaroya Research Institute
Wednesday, Jun 19
6:15 pm

W. 71 - Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire
Mohsen Khosravi-Maharlooe, MD/MSc – Columbia University; Aleksander Obradovic, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Aditya Misra – Columbia University; Keshav Motwani, Ph.D. – University of Florida; Markus Holzl, Ph.D. – Columbia University; Howard R. Seay, Ph.D. – University of Florida; Susan DeWolf, MD – Columbia University; Grace Nauman, M.A., M. Phil. – Columbia Center for Translational Immunology, Department of Medicine; Columbia University Department of Microbiology and Immunology, Columbia University Medical Center; Nichole Danzl, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Hao Wei Li, PhD – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Siu-hong Ho, Ph.D. – Columbia University; Robert Winchester, MD – Columbia University; Yufeng Shen, Ph.D. – Columbia University; Todd M. Brusko, Ph.D. – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Megan Sykes, M.D. – Columbia Center for Translational Immunology, Department of Medicine; Department of Microbiology & Immunology; Department of Surgery, Columbia University Medical Center
Wednesday, Jun 19
6:15 pm

W. 74 - An optimized method for expansion and retroviral transduction of mouse regulatory T cells
May Q. Wong, BSc – University of British Columbia; Dan Wu, BSc – University of British Columbia; Jens Vent-Schmidt, BSc – University of British Columbia; Dominic A. Boardman, PhD – Department of Surgery, University of British Columbia; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia; Theodore Steiner, MD – University of British Columbia
Wednesday, Jun 19
6:15 pm

W. 76 - Development and clinical evaluation of a recombinant vaccine for hRSV
Jorge Soto, Phd Student – Millenium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile. Multinational FOCIS Centers of Excellence.; Nicolás M S. Gálvez Arriagada – Pontificia Universidad Católica de chile; Susan M. Bueno – Pontificia Universidad Católica de Chile; Pablo Gonzalez – Pontificia Universidad Católica de Chile; Claudia A. Riedel – Universidad Andrés Bello; Alexis M. Kalergis – Pontificia Universidad Católica de Chile
Wednesday, Jun 19
6:15 pm

W. 122 - Generation of CD8+ and CD4+ Regulatory T Cells from Human Pluripotent Stem Cells
Lea Flippe – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; Anne Gaignerie – iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Séverine Bézie – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Ignacio Anegon – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Laurent David – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France, iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Carole Guillonneau – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO
Wednesday, Jun 19
6:15 pm

W. 125 - BMP signaling pathway modulation promotes tolerance in GvHD and prevents colitis.
Magdiel Pérez-Cruz, PhD – Stanford University; Bettina Iliopoulou, PhD – Stanford University; Katie Hsu, MS – Stanford University; Hsin-Hsu Wu, MD – Stanford University; Tom Erkers, PhD – Stanford University; Kavya Swaminathan, PhD – Stanford University; Sai-Wen Tang, PhD – Stanford University; Wendy Pang, PhD – Stanford University; Neeraja Kambham, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine; Rosemarie H. Dekruyff, PhD – Stanford University; Gordon J. Freeman, PhD – Dana-Farber Cancer Institute; Everett Meyer, MD, PhD – Stanford University
Wednesday, Jun 19
6:15 pm

Exhibit and Poster Reception (authors present)
Location: Salon E, 4th Floor
Sponsored By:
Wednesday, Jun 19
6:15 pm

W. 1 - Anti-inflammatory Role of 6-Gingerol In Mouse Model of House Dust Mite (HDM)-Induced Asthma.
Babajide Oluwaseun. Ajayi – Bowen University; Anuoluwapo Adeshina – All saint University School of medicine; Olatunde Farombi – University of Ibadan
Wednesday, Jun 19
6:15 pm

W. 2 - A Novel Role for Long noncoding RNAs in Airway Responses to Type 2 Cytokines.
Grace Kwon – The jackson laboratory for genomic medicine; Marina Yurieva – The jackson laboratory for genomic medicine; Adam Williams, Ph.D. – The Jackson Laboratory for Genomic Medicine
Wednesday, Jun 19
6:15 pm

W. 3 - Alternative dosing strategy of omalizumab during multi-allergen oral-immunotherapy in multi-food allergic patients
Sayantani B. Sindher, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Andrew Long, PharmD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Natasha Purington, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Divya Kumar, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Dana Tupa, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Katherine L. O’Laughlin, MN – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Margaret A Woch, RDN – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Tiffany Tan, BS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; R. Sharon Chinthrajah, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Stacey Skura, RN, CCRC – Division of Allergy, Immunology & Rheumatology, Department of Pediatrics David Geffen, School of Medicine at UCLA; Maria Garcia-Lloret, MD – Division of Pediatric Allergy/Immunology and Rheumatology, Department of Pediatrics, UCLA School of Medicine; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Wednesday, Jun 19
6:15 pm

W. 4 - CD9+ Regulatory B cells Induce T Cell Apoptosis via IL-10 and are Reduced in Severe Asthmatic Patients
Carole Brosseau – Centre de Recherche en Transplantation et Immunologie; Maxim Durand – Center for Research in Transplantation and Immunology - INSERM UMR1064 - Nantes; Luc Colas – Centre de Recherche en Transplantation et Immunologie; Eugénie Durand – Center for Research in Transplantation and Immunology - INSERM UMR1064 - Nantes; Aurore Foureau – CHU Nantes; Gregory Bouchaud, PhD – INRA; Antoine Magnan – CHU Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Wednesday, Jun 19
6:15 pm

W. 5 - Change in immune markers after rapid desensitization to a minimum oral immunotherapy maintenance dose in multi-food allergic patients
Sayantani B. Sindher, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Andrew Long, PharmD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Natasha Purington, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Divya Kumar, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Dana Tupa, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Katherine L. O’Laughlin, MN – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Margaret A Woch, RDN – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Tiffany Tan, BS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; R. Sharon Chinthrajah, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Maria Garcia-Lloret, MD – Division of Pediatric Allergy/Immunology and Rheumatology, Department of Pediatrics, UCLA School of Medicine; Stacey Skura, RN, CCRC – Division of Allergy, Immunology & Rheumatology, Department of Pediatrics David Geffen, School of Medicine at UCLA; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Wednesday, Jun 19
6:15 pm

W. 6 - Characterization of a Novel Clinical Assay for Peanut-Specific Immunoglobulin A in the Stool
Elise Liu, MD – Yale University School of Medicine; Biyan Zhang – Yale University School of Medicine; Stephanie Eisenbarth, MD, PhD – Yale University School of Medicine
Wednesday, Jun 19
6:15 pm

W. 7 - Follicular Regulatory T Cells Promote the Germinal Center Reaction and IgE Response in a Peanut Food Allergy Model
Markus Xie – Indiana University School of Medicine; Alexander Dent – Indiana University School of Medicine
Wednesday, Jun 19
6:15 pm

W. 8 - Computational Identification and Comparison of GR+ Circulating Leukocyte Subsets in Healthy and Asthmatic Adolescents in Response to Exercise
Yu Qian, PhD – J. Craig Venter Institute; Aishwarya Mandava, MS – J. Craig Venter Institute; Kim Lu, MD – University of California, Irvine; Frank Zaldivar, PhD – University of California, Irvine; Dan Cooper, MD – University of California, Irvine; Richard Scheuermann, PhD – J. Craig Venter Institute
Wednesday, Jun 19
6:15 pm

W. 9 - Effect of anti-IgE treatment in Peripheral T Cell Subpopulations in Chronic Urticaria
Cristina Alejandra López- Rodríguez, Ms – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Nathalie Depreux, MD – Allergy Unit. Germans Trias i Pujol University Hospital and Research Institute, FOCIS Center of Excellence- UAB- Barcelona; Armando Ruiz, Mr – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona; Isabel Bielsa, MD – Dermatology Division. Germans Trias i Pujol University Hospital and Research Institute, FOCIS Center of Excellence- UAB- Barcelona; Bibiana Quirant, MSc – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Eva M Martinez-Caceres, PhD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Aina Teniente-Serra, PhD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra
Wednesday, Jun 19
6:15 pm

W. 10 - Combined blockade of IL13 or IL5 with IL33 leads to a greater inhibition of Type-2 inflammation over inhibition of either pathway alone
Rajita Pappu, PhD – GENENTECH; Vladimir Ramirez-Carrozzi, PhD – GENENTECH
Wednesday, Jun 19
6:15 pm

W. 11 - Increased Allergen Specific CD8+ T Cells in Peanut Allergic People
Yu Wong, MD, PhD – Stanford University; Xiaoying Zhou, PhD – Stanford University; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Wednesday, Jun 19
6:15 pm

W. 12 - Airway Dendritic Cells Distinguish Allergic Asthmatics from Allergic Controls
Jehan Alladina, MD – Massachusetts General Hospital; Daniel Hamilos, MD – Massachusetts General Hospital; Andrew Luster, MD, PhD – Center for Immunology and Inflammatory Disease; Benjamin Medoff, MD – Massachusetts General Hospital; Josalyn Cho, MD – University of Iowa
Wednesday, Jun 19
6:15 pm

W. 13 - Administration of an Anti-Interleukin-13 (IL-13) Antibody Significantly Attenuates Esophageal Eosinophilic Infiltration and Systemic Inflammation in a Mouse Model of Eosinophilic Esophagitis
Kate L. Paget, PhD – Neurosciences TCoE, Celgene Corporation; Carlos R. Lopez, PhD – Neurosciences TCoE, Celgene Corporation; Stephanie E. Smith, BS – Neurosciences TCoE, Celgene Corporation; Julia Oh, BS – Neurosciences TCoE, Celgene Corporation; David M. Guimond, PhD – Neurosciences TCoE, Celgene Corporation; Iliana Ruiz, AS – Neurosciences TCoE, Celgene Corporation; Kevin C. Dines, PhD – Neurosciences TCoE, Celgene Corporation; Marcos W. Steinberg, PhD – Neurosciences TCoE, Celgene Corporation
Wednesday, Jun 19
6:15 pm

W. 14 - IRF4 Expression by Lung Dendritic Cells Drives a Th2 Program throughout the Effector Allergic Response, but is not Essential during the Memory Response
Daniel F. Camacho, MS – University of Chicago; Esther Wang – University of Chicago; Chanie L. Howard, MS – University of Chicago; Donna C. Decker, BS – University of Chicago; Kelly M. Blaine, MS – University of Chicago; Eli P. Darnell, MD – University of Chicago; Cara L. Hrusch, PhD – University of Chicago; James J. Moon, PhD – Harvard University; Anne I. Sperling, PhD – University of Chicago
Wednesday, Jun 19
6:15 pm

W. 15 - Targeting the IL-7Rα as a potential therapeutic approach for allergic asthma
Hoa L. Mai, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Thi Van Ha Nguyen, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Gregory Bouchaud, PhD – INRA; Kelly Henrio, MS – INSERM UMR 1087, Institut du Thorax, Nantes; Marie-Aude Cheminant – INSERM UMR 1087, Institut du Thorax, Nantes; Antoine Magnan, MD – INSERM UMR 1087, Institut du Thorax, Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Wednesday, Jun 19
6:15 pm

W. 16 - Comprehensive Mapping of Immune-Epithelial Interactions in Severe Asthma Using Machine Learning Analysis of Multi-‘omics Data
Matthw Camiolo, MD, PhD – University of Pittsburgh; Xiaoying Zhou, PhD – Stanford University; Timothy B. Oriss, PhD – University of Pittsburgh; Wei Chen, PhD – Children's Hospital of Pittsburgh; Jay Kolls, MD – Tulane University School of Medicine; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Sally Wenzel, MD – University of Pittsburgh; Anuradha Ray, PhD – University of Pittsburgh
Wednesday, Jun 19
6:15 pm

W. 17 - Phenotypic and Functional Alterations of Monocytes in Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia
Mio Hamatani, MD – Department of Neurology, Kyoto University Graduate School of Medicine; Hirofumi Yamashita, MD, PhD – Japanese Red Cross Wakayama Medical Center; Hirofumi Ochi, MD, PhD – Department of Geriatric medicine, Ehime University Graduate School of Medicine; Shinji Ashida, MD – Department of Neurology, Kyoto Prefectural University of Medicine; Yuichiro Hashi, MD – Department of Neurology, Kansai Medical University Medical Center; Chihiro Fujii, MD, PhD – Department of Neurology, Kyoto Prefectural University of Medicine; Masanori Nakagawa, MD, PhD – North Medical Center, Kyoto Prefectural University of Medicine; Toshiki Mizuno, MD, PhD – Department of Neurology, Kyoto Prefectural University of Medicine; Ryosuke Takahashi, MD, PhD – Department of Neurology, Kyoto University Graduate School of Medicine; Takayuki Kondo, MD, PhD – North Medical Center, Kyoto Prefectural University of Medicine
Wednesday, Jun 19
6:15 pm

W. 18 - Response to Plasmapheresis is Predicted by the Th1 Cell Frequency in the Blood in Multiple Sclerosis
Kimitoshi Kimura, MD, PhD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Youwei Lin, MD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Wakiro Sato, MD, PhD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Ryosuke Takahashi, MD, PhD – Department of Neurology, Kyoto University Graduate School of Medicine
Wednesday, Jun 19
6:15 pm

W. 19 - Synergistic Effect of Vitamin D3-Tolerogenic Dendritic Cells Combined with Interferon-beta in Multiple Sclerosis
Bibiana Quirant-Sánchez, MSc – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; María José Mansilla, PhD – Germans Trias i Pujol Research Institute; Juan Navarro-Barriuso, MSc – Germans Trias i Pujol Research Institute; Silvia Presas-Rodríguez, MD – Multiple Sclerosis Unit. Neurology Department, Hospital Germans Trias i Pujol, Badalona; Alicia Ardiaca-Martínez, MSc – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Aina Teniente-Serra, PhD – Immunology Division. LCMN. Germans Trias i Pujol University Hospital and Research Institute. FOCIS Center of Excellence- UAB- Barcelona and Department of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Bellaterra; Irene Bragado-Trigo, MD – Multiple Sclerosis Unit. Neurology Department, Hospital Germans Trias i Pujol, Badalona; Cristina Ramo-Tello, MD, PhD – Multiple Sclerosis Unit. Neurology Department, Hospital Germans Trias i Pujol, Badalona; Eva M. Martínez-Cáceres, MD, PhD – Germans Trias i Pujol Research Institute
Wednesday, Jun 19
6:15 pm

W. 20 - Systems immunology using Mass Cytometry identified functional rewiring of the architecture of the Immunome in refractory epilepsy
Kumar Pavanish – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Derrick Chan Wei Shih – Paediatrics Academic Clinical Programme, KK Women’s and Children’s Hospital; Amanda Lim – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre, Singapore; Bhairav Paleja – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre, Singapore; Simon Ling – Paediatrics Academic Clinical Programme, KK Women’s and Children’s Hospital; Liyun Lai – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Thaschawee Arkachaisri, MD, FACR – KK Women’s and Children’s Hospital; Joo Guan Yeo, PhD, MBBS, MMed (Paediatrics), MRCPCh (UK) – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre
Wednesday, Jun 19
6:15 pm

W. 21 - The modulation IL-17/IL-10 balance in experimental autoimmune encephalomyelitis through thyroid hormone receptor beta signaling
Yoshimitsu Doi, MD PhD – National Institute of Neuroscience, National Center of Neurology and Psychiatry
Wednesday, Jun 19
6:15 pm

W. 22 - TIGIT signaling restores suppressor function of Th1-Tregs
Liliana E. Lucca, PhD – Yale School of Medicine; Pierre-Paul Axisa, DVM, PhD – Yale School of Medicine; Emily Singer, BA – Yale School of Medicine; Neal Nolan, Medical Student – Yale School of Medicine; Margarita Dominguez-Villar, PhD – Yale School of Medicine; David Hafler, MD – Yale School of Medicine
Wednesday, Jun 19
6:15 pm

W. 23 - TMEM119-tdTomato reporter mice: a new tool to study microglia in MS and other neurodegenerative diseases
Chunsheng Ruan, PhD – Columbia University; Linlin Sun, PhD – Columbia University; Lien Beckers, PhD – Columbia University; Alexandra Kroshilina, BS – Columbia University; Elizabeth Bradshaw, PhD – Columbia University Medical Center; Guang Yang, PhD – Columbia University; Wassim Elyaman, PhD – Columbia University Medical Center
Wednesday, Jun 19
6:15 pm

W. 24 - Topical immunomodulation for the treatment of experimental autoimmune encephalomyelitis (EAE)
Paulina Piesik – BC Children's Hospital Research; Laura Sly – BC Children's Hospital Research; Jan Dutz – BC Children's Hospital Research
Wednesday, Jun 19
6:15 pm

W. 25 - Trajectories of effector T cell (Teff) and regulatory T cells (Treg) imbalance in pediatric multiple sclerosis
Ina Mexhitaj, BSc – Perelman School of Medicine, University of Pennsylvania; Rui Li, MD, PhD – Perelman School of Medicine, University of Pennsylvania; Julia O'Mahony, BSc – Hospital for Sick Children, University of Toronto; Brenda Banwell, MD – Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania; Amit Bar-Or, MD – Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania
Wednesday, Jun 19
6:15 pm

W. 26 - Treatment with ILT3.Fc of C57BL/6 mice delays the onset and attenuates the evolution of MOG35-55-induced-EAE
Zheng Xu, PhD – Columbia University; Chun-Chieh Lin, MD – Columbia University; George Vlad, PhD – Columbia University; Nicole Suciu-Foca, PhD – Columbia University
Wednesday, Jun 19
6:15 pm

W. 27 - Foxp3+ regulatory T cells use heparanase to access IL-2 bound to extracellular matrix at sites of autoimmune inflammation
Paul Bollyky, MD, PhD – Stanford University School of Medicine; Hedwich Kuipers, PhD – Stanford University School of Medicine; Ievgen Koliesnik, PhD – Stanford University School of Medicine; Gernot Kaber, PhD – Stanford University; Carlos O. Medina, BS – Stanford University School of Medicine; David Pitt, PhD – Yale; Magdiel Pérez-Cruz, PhD – Stanford University; Everett Meyer, MD, PhD – Stanford University; David Hafler, MD – Yale School of Medicine; K. Christopher Garcia, PhD – Stanford University; Lawrence Steinman, MD, PhD – Stanford University; Gerald Nepom, PhD – Immune Tolerance Network; Thomas Wight, PhD – Benaroya Research institute
Wednesday, Jun 19
6:15 pm

W. 28 - Invalidation of the ICOS costimulation pathway in NOD mice : shift of autoimmunity from diabetes to myositis and oxydative stress in target tissue.
Catalina Abad – Normandie Univ, UNIROUEN, INSERM, U1234, IRIB, Rouen, France; Alain Meyer – 2Strasbourg University Hospital, Reference center for rare autoimmune diseases, Department of rheumatology, Strasbourg, France; Laurent Drouot – Normandie Univ, UNIROUEN, INSERM, U1234, IRIB, Rouen, France; Gwladys Bourdenet – Normandie Univ, UNIROUEN, INSERM, U1234, IRIB, Rouen, France; Christian Boitard – INSERM, U1016, Paris, France; Olivier Boyer – Faculty of Medicine _ University of Rouen Normandy
Wednesday, Jun 19
6:15 pm

W. 29 - Mass cytometry reveals elevated phosphorylated STAT3 (pSTAT3) in circulating CD4+ T cells during active Psoriatic Arthritis
Claudia Macaubas, PhD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Shamma Rahman, PhD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Devy Zisman, MD – Rheumatology Unit Carmel Medical Center and Ruth and Bruce Faculty of Medicine Technion Haifa, Israel; Elizabeth Mellins, MD PhD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Wednesday, Jun 19
6:15 pm

W. 30 - Microenvironment driven re-shaping of pathogenic HLA-DR+ T subsets in active Juvenile Idiopathic Arthritic patients
Jing Yao Leong, PhD – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Kumar Pavanish – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Phyllis Chen – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre,; Joo Guan Yeo, PhD, MBBS, MMed (Paediatrics), MRCPCh (UK) – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Camillus Chua – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Sharifah Nur Hazirah – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Thaschawee Arkachaisri, MD, FACR – KK Women’s and Children’s Hospital; Alessandro Consolaro, MD – Second Paediatric Division, University of Genoa and G Gaslini Institute, Genova, Italy; Marco Gattorno, MD – Second Paediatric Division, University of Genoa and G Gaslini Institute, Genova, Italy; Alberto Martini, MD, Prof – Second Paediatric Division, University of Genoa and G Gaslini Institute, Genova, Italy; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre
Wednesday, Jun 19
6:15 pm

W. 31 - Molecular and cellular biomarkers that discriminate juvenile idiopathic arthritis from septic arthritis
Nadege Nziza, PhD student – INSERM U1183 and Arthritis R&D; Maïlys Cren, Engineer – INSERM U1183 and University of Montpellier; Aurelia Carbasse, Doctor – University Hospital of Montpellier; Perrine Mahe, Doctor – University Hospital of Montpellier; Marion Delpont, Doctor – University Hospital of Montpellier; Djamel Louahem, Doctor – University Hospital of Montpellier; Jerome Pene, Doctor – INSERM U1183 and University of Montpellier; Hughes Chevassus, Doctor – University Hospital of Montpellier; Mirna Khalil, Engineer – University Hospital of Montpellier; Thibault Mura, Doctor – La Colombière Hospital; Christian Jorgensen, Professor – INSERM U1183, University of Montpellier and University Hospital Lapeyronie; Pascale Louis-Plence, Doctor – INSERM U1183 and University of Montpellier; Eric Jeziorski, Doctor – University Hospital of Montpellier; Isabelle Duroux-Richard, Doctor – INSERM U1183 and University of Montpellier; Florence Apparailly, Professor – INSERM U1183, University of Montpellier and University Hospital Lapeyronie
Wednesday, Jun 19
6:15 pm

W. 32 - Orphan Receptors in an Orphan Disease: Identification of the NR4A Family as Key Players of Dendritic Cell Dysregulation in Systemic Sclerosis
Nila Servaas, MSc – University Medical Centre Utrecht; Eleni Chouri – University Medical Center Utrecht; Rina Kommer-Wichers – University Medical Center Utrecht; Maarten van der Kroef – University Medical Center Utrecht; Alsya Affandi – University Medical Center Utrecht; Sandra Silva-Cardoso – University Medical Center Utrecht; Tiago Carvalheiro – University Medical Center Utrecht; Marta Cossu – University Medical Center Utrecht; Nadia Vazirpanah – University Medical Center Utrecht; Lorenzo Beretta – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico; Marzia Rossato – University of Verona; Marianne Boes – University Medical Center Utrecht; Aridaman Pandit – University Medical Centre Utrecht; Timothy Radstake – University Medical Center Utrecht
Wednesday, Jun 19
6:15 pm

W. 33 - Patient Characteristics and Current Management of Systemic Lupus Erythematosus Patients in a Large, Representative US-based Real World Cohort
Philip Ballentine, BA – OM1; Kathleen M. Mortimer, ScD, MPH – OM1; Kathryn Starzyk, ScM – OM1; Thomas Brecht, BA – OM1; Shannon Cerf, PharmD, MBA – OM1; Richard Gliklich, MD – OM1
Wednesday, Jun 19
6:15 pm

W. 34 - Performance of automated indirect immunofluorescence assay for antinuclear autoantibodies in cancer patients
Younhee Park – Yonsei University College of Medicine; Hyon-Suk Kim – Yonsei University College of Medicine
Wednesday, Jun 19
6:15 pm

W. 35 - PP2A B55ß limits the lifespan of self-reactive and pathogen-specific CD8 T cells through the pro-apoptotic molecule Hrk
Noé Rodríguez-Rodríguez, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; J. Alejandro Cisneros-Segura, MSc – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; George Tsokos, MD. – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Jorge Alcocer-Varela, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Florencia Rosetti, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Jose C. Crispin, MD, PhD – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Wednesday, Jun 19
6:15 pm

W. 36 - Systemic Sclerosis is a Disease of a Prematurely Senescent, Inflammatory and Activated Immunome
Bhairav Paleja – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre, Singapore; Andrea Low – Singapore General Hospital/ SingHealth Pte Ltd; Kumar Pavanish – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Suzan Saidin – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre; Ahmad Bin Mohamed Lajam – Translational Immunology Institute, Singhealth/Duke-NUS Acedemic Medical Centre; Sharifah Nur Hazirah – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Camillus Chua – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Liyun Lai – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre
Wednesday, Jun 19
6:15 pm

W. 37 - Tissue-Anchored Indoleamine 2,3 Dioxygenase Locally Suppresses Inflammation
Sabrina Freeman, BS – University of Florida; Evelyn Bracho-Sanchez, PhD – University of Florida; Fernanda Rocha, DVM – University of Florida; Shannon Wallet, PhD – East Carolina University; Gregory Hudalla, PhD – University of Florida; Benjamin G. Keselowsky, PhD – University of Florida
Wednesday, Jun 19
6:15 pm

W. 38 - Transcriptional correspondence between the activation profiles of human TH1 cells generated in vitro and their counterparts generated in vivo
Joanna DiSpirito – Rheos Medicines Inc; Vivek Kaimal – Rheos Medicines Inc; Wenjie Jin – Institute for Research in Biomedicine; Giada Zoppi – Institute for Research in Biomedicine; Edward Driggers – Rheos Medicines, Inc; Laurence Turka – Rheos Medicines, Inc; Roger Geiger – Institute for Research in Biomedicine; Hozefa Bandukwala – Rheos Medicines, Inc
Wednesday, Jun 19
6:15 pm

W. 39 - Ultra-Efficient Short Read Sequencing of Immune Receptor Repertoires
Janelle M. Montagne, M.S. – Division of Immunology, Department of Pathology, Johns Hopkins University School of Medicine; Xuwen Alice Zheng – Division of Immunology, Department of Pathology, Johns Hopkins University School of Medicine; Iago Pinal-Fernandez, M.D., Ph.D. – Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulations, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health and Department of Neurology, Johns Hopkins University School of Medicine; Jose C. Milisenda, M.D., Ph.D. – Internal Medicine Department, Hospital Clinic, Universitat de Barcelona and and Centro de Investigación Médica en Red Enfermedades Raras; Lisa Christopher-Stine, M.D., Ph.D. – Division of Rheumatology, Johns Hopkins University School of Medicine; Thomas E. Lloyd, M.D., Ph.D. – Department of Neurology, Johns Hopkins University School of Medicine; Andrew L. Mammen, M.D., Ph.D. – Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulations, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health and Department of Neurology, Johns Hopkins University School of Medicine; H. Benjamin Larman, Ph.D. – Division of Immunology, Department of Pathology, Johns Hopkins University School of Medicine
Wednesday, Jun 19
6:15 pm

W. 40 - Unveiling Novel Biomarkers for Rheumatoid Arthritis Using Machine Learning on Gene Expression Data
Dmitry Rychkov, PhD – UCSF; Jessica Neely, MD – UCSF; Cindy Lin, MS – Stanford University; Marina Sirota, PhD – UCSF
Wednesday, Jun 19
6:15 pm

W. 41 - Whole Blood Phenotype and Signaling Analyses Reveal Ethnicity Dependent Dysregulation in SLE Patients with Variable Disease Activity
Samantha Slight-Webb, PhD – Oklahoma Medical Research Foundation; Miles Smith, PhD – Oklahoma Medical Research Foundation; Eliza Chakravarty, MD – Oklahoma Medical Research Foundation; Cristina Arriens, MD – Oklahoma Medical Research Foundation; Teresa Aberle, PAC – Oklahoma Medical Research Foundation; Holden T. Maecker, PhD – Stanford University; Pj Utz, MD – Stanford University, School of Medicine; Judith James, MD, PhD – Oklahoma Medical Research Foundation; Joel Guthridge, PhD – Oklahoma Medical Research Foundation
Wednesday, Jun 19
6:15 pm

W. 42 - Dissecting the mechanisms responsible for the generation of regulatory versus pathogenic human CD4+ T cells by TLR9-activated plasmacytoid dendritic cells
Simone Caielli – Drukier Institute for Children Health - Weill Cornell Medicine; Zhaohui Xu – Baylor Research Institute; Jacques Banchereau – Jackson Laboratory for Genomic Medicine; Virginia Pascual – Drukier Institute for Children's Health
Wednesday, Jun 19
6:15 pm

W. 43 - Targeting pre-existing anti-transgene T cell response for effective gene therapy of Mucopolysaccharidosis type-I
Giorgia Squeri – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Laura Passerini – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Francesca Ferro – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Cecilia Laudisa – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Alessandro Aiuti – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Maria Ester Bernardo – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Bernhard Gentner – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Luigi Naldini – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Andrea Annoni – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Alessandra Biffi – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Silvia Gregori, Member Number: 36467805 – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
Wednesday, Jun 19
6:15 pm

W. 44 - Dissecting and Reconstructing the Human Thymus-Designing Roadmaps and Building Blocks for Functional Thymic Organoids
Hui Gai, MD – Stanford University; Yogendra Verma, MS – Stanford University; Ellie Kim, BS – Stanford University; Sarah Heilshorn, PhD – Stanford University; Ken Weinberg, MD – Stanford Uiversity; Georg Hollander, MD – University of Oxford; Maria Grazia Roncarolo, MD PhD – Stanford University; Vittorio Sebastiano, PhD – Stanford University; Katja Gabriele. Weinacht, MD PhD – Department of Pediatrics, Stem Cell Transplantation, at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Wednesday, Jun 19
6:15 pm

W. 45 - Potential for NGS based MHC Typing To Reduce Incidence and or Severity of Graft Vs Host Disease in Hematopoietic Stem Cell Transplantation
Siva Kanangat, Ph.D. D[ABHI] – Rush University Medical Center; Ina Kurbegovic-Skaljic, MS – Rush University Medical Center; Hamama Bushra, MBBS – Rush University Medical Center
Wednesday, Jun 19
6:15 pm

W. 46 - Regulatory B cell generation from human Induced Pluripotent Stem Cells with a repressible granzyme B expression
Florian Dubois – Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, université de Nantes, Nantes; Anne Gaignerie – Institut de Transplantation Urologie Néphrologie, Nantes, France, iPSC corefacility, University of Nantes; Lea Flippe – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; Jean-Marie Heslan – Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, GenoCellEdit, Nantes; Laurent Tesson – Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, GenoCellEdit, Nantes; Mélanie Chesneau – CRTI UMR1064, INSERM, Université de Nantes; Fabienne Haspot-degauque – Centre de Recherche en Transplantation et Immunologie UMR 1064, INSERM, université de Nantes, Nantes; Sophie Conchon – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Laurent David – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France, iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Wednesday, Jun 19
6:15 pm

W. 47 - Pediatric acute myeloid leukemia blasts are killed by engineered type 1 regulatory cells developed to mitigate graft-vs-host disease
Brandon Cieniewicz, Ph. D. – Stanford University; Pauline Chen – Stanford Univeristy; Alma-Martina Cepika, M.D., Ph. D. – Stanford University; Molly Uyeda – Stanford University; Rosa Bacchetta, MD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Silvia Gregori, Member Number: 36467805 – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Norman Lacayo, M.D. – Stanford University; Maria Grazia Roncarolo, MD PhD – Stanford University
Wednesday, Jun 19
6:15 pm

W. 48 - CRISPR-based Therapy for IPEX Syndrome as a Model of Genetic Autoimmunity
Marianne E. Goodwin, PhD – Stanford University; Esmond Lee, MS – Stanford University; Uma Lakshmanan, MS – Stanford University; Suzette Shipp, MS – Stanford University; Matthew Porteus, MD, PhD – Stanford University; Maria Grazia Roncarolo, MD PhD – Stanford University; Rosa Bacchetta, MD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Wednesday, Jun 19
6:15 pm

W. 49 - Absence of AMP-activated Protein Kinase (AMPK) in Donor T Cells Minimizes Graft-versus-host Disease without Compromising Graft-versus-leukemia Responses or Impairing Immune Reconstitution
Craig Byersdorfer, MD/PhD – University of Pittsburgh; Kevin Beezhold, PhD – University of Pittsburgh School of Medicine; Pailin Chiaranunt – University of Pittsburgh School of Medicine; Katelyn Paz, PhD – University of Minnesota; Nathan Moore, MD – University of Washington; Brown Rebecca – University of Pittsburgh School of Medicine; Andrea Dobbs, MS – University of Pittsburgh; Bruce Blazar, MD – University of Minnesota
Wednesday, Jun 19
6:15 pm

W. 50 - Ex vivo Generated Lymphoid Progenitors for Immune Reconstitution in the Context of Allogeneic Transplantation and Gene Therapy
Isabelle André – INSERM; Ranjita Moirangthem – INSERM; Kuiying Ma – INSERM; Juliette Olivre – Institut Imagine; Anne Cordesse – INSERM; Corinne de Chappedelaine – INSERM; Sabrina Lizot – INSERM; Chantal Lagresle-Peyrou – INSERM; Tayebeh-Shabi Soheili – INSERM; Marina Cavazzana – INSERM
Wednesday, Jun 19
6:15 pm

W. 51 - Identification of unique stem cell niche-residential Tregs acting as stem cell protectants–promising therapeutic targets for transplantation, tissue injury, and cancer
Yuichi Hirata, MD PhD – Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons; Miwako Kakiuchi, MD PhD – Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons; Kazuhiro Furuhashi, MD PhD – Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons; Hiroshi Ishii, MD PhD – Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons; Hao Wei Li, PhD – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Sandra Pinho, PhD – 5Department of Medicine, Albert Einstein College of Medicine; Lei Ding, PhD – Columbia University College of Physicians and Surgeons; Simon Robson, MD PhD – Liver Center and Transplantation Institute, Beth Israel Deaconess Medical Center, Harvard Medical School; Paul Frenette, MD – Albert Einstein College of Medicine; Joji Fujisaki, MD PhD – 1Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons
Wednesday, Jun 19
6:15 pm

W. 52 - Molecular Basis for Autoreactive T Effector Memory Differentiation in Type 1 Diabetes
Irma Pujol-Autonell, PhD – King's College London; Roman Baptista – King's College London; Anna Lorenc, PhD – King's College London; Domenico Cozzetto, PhD – National Institute of Health Research Biomedical Research Centre; Susanne Heck, PhD – National Institute of Health Research Biomedical Research Centre; Alka Saxena, PhD – National Institute of Health Research Biomedical Research Centre; Martin Eichmann, PhD – King's College London; Lorraine Yeo, PhD – King's College London; Mark Peakman, PhD – King's College London
Wednesday, Jun 19
6:15 pm

W. 53 - Oral Vaccination with Fc-coupled Preproinsulin Prevents Type 1 Diabetes
Noémie Corcos – INSERM U1016; Slobodan Culina, PhD – CEA; Cassandra Lavaud – INSERM U1016; Sylvaine You, PhD – INSERM U1016; Roberto Mallone, MD, PhD – INSERM U1016
Wednesday, Jun 19
6:15 pm

W. 54 - PD1 and PD-L1 in Graves’ disease: new clues for pathogenesis
Daniel Alvarez-Sierra – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Carmen de Jesús-Gil – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Ana Marín-Sánchez; Paloma Ruiz-Blázquez – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Carmela Iglesias – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR); Paolo Nuciforo – Vall d'Hebron Institute of Oncology; Óscar González – Hospital Universitario Vall d'Hebron; Anna Casteras – Hospital Universitario Vall d'Hebron; Gabriel Obiols – Hospital Universitario Vall d'Hebron; Ricardo Pujol-Borrell – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB)
Wednesday, Jun 19
6:15 pm

W. 55 - Redirecting TCR specificity in regulatory T cells toward class I HLA-restricted islet antigens in type 1 diabetes
Yannick Daniel. Mueller, MD-PhD – UCSF; Roxxana Valencia – UCSF; Shen Dong, PhD – UCSF; Theo Roth – UCSF; David Nguyen, MD – UCSF; Emilie Ronin, PhD – UCSF; Alexander Marson, MD, PhD – University of California San Francisco; Jeffrey Bluestone, PhD – UCSF; Qizhi Tang, Ph.D. – University of California San Francisco
Wednesday, Jun 19
6:15 pm

W. 56 - Single cell characterization of CD8 T-cells and their role in disease progression in Type 1 Diabetes
Hai T. Nguyen, PhD – Benaroya Research Institute; Matthew Dufort, PhD – Benaroya Research Institute; Gabriele Blahnik, MS – Benaroya Research Institute; Hannah DeBerg, PhD – Benaroya Research Institute; Cate Speake, PhD – Benaroya Research Institute; Carla Greenbaum, MD – Benaroya Research Institute; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; Eddie James, Ph.D. – Benaroya Research Institute at Virginia Mason
Wednesday, Jun 19
6:15 pm

W. 57 - The Mechanism by which IL-17A contributes to MMP-9 production during diabetic retinopathy
Thomas E. Zapadka – Case Western Reserve University-School of Medicine; Sarah I. Lindstrom, BS – Case Western Reserve University-School of Medicine; Dawn G. Smith, BS – Case Western Reserve University-School of Medicine; Brooklyn E. Taylor – Case Western Reserve University-School of Medicine; Chieh A. Lee, BS – Case Western Reserve University-School of Medicine; Patricia R. Taylor, PhD – Case Western Reserve University-School of Medicine
Wednesday, Jun 19
6:15 pm

W. 58 - The PTPN22 R620W SNP is associated with alterations in the frequency and phenotypes of islet antigen-reactive CD4 T cells in T1D.
Elisa Balmas, PhD – Benaroya Research Institute at Virginia Mason; Virginia Muir, Ph.D. – Benaroya Research Institute at Virginia Mason; Kirsten Balmas, PhD – Benaroya Research Institute at Virginia Mason; Cate Speake, PhD – Benaroya Research Institute; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; Jane H. Buckner, M.D. – Benaroya Research Institute at Virginia Mason; Karen Balmas, PhD – Benaroya Research Institute at Virginia Mason
Wednesday, Jun 19
6:15 pm

W. 59 - The Role of Aire in the selection of Regulatory T cells in Diabetes
Jennifer Anne. Bridge, PhD. MS. BSc. – The University of California, San Francisco Diabetes Center; Benjamin Yuen, PhD – UCSF; Shen Dong, PhD – UCSF; Frances Crawford, PhD – National Jewish Health, Denver, CO; John Kappler, PhD – National Jewish Health, Denver, CO; Jeffrey Bluestone, PhD – UCSF; Mark Anderson, MD. PhD – UCSF
Wednesday, Jun 19
6:15 pm

W. 60 - Pancreatic and β cell responses to checkpoint inhibition
Ana Luisa Perdigoto, MD, PhD – Yale University; Daniel Burkhardt – Yale University; Nancy Kirkiles-Smith, PhD – Yale University; Angeliki Stamatouli, MD – Virginia Commonwealth University; Marie Robert, MD – Yale University; John Sinard, MD, PhD – Yale University; Smita Krishnaswamy, PhD – Yale University; Gary Israel, MD – Yale University; Jordan Pober, MD, PhD – Yale University; Kevan Herold, MD – Yale Univeristy
Wednesday, Jun 19
6:15 pm

W. 61 - Exhaustion of Autoreactive CD8+ T Cells Distinguishes Slow Progression of Type 1 Diabetes
Alice Wiedeman, PhD – Benaroya Research Institute; Virginia Muir, Ph.D. – Benaroya Research Institute at Virginia Mason; Mario Rosasco, PhD – Benaroya Research Institute; Hannah DeBerg, PhD – Benaroya Research Institute; Scott Presnell, PhD – Benaroya Research Institute; Bertrand Haas, PhD – Benaroya Research Institute; Matthew Dufort, PhD – Benaroya Research Institute; Cate Speake, PhD – Benaroya Research Institute; Carla Greenbaum, MD – Benaroya Research Institute; Elisavet Serti, PhD – Immune Tolerance Network; Gerald Nepom, PhD – Immune Tolerance Network; Gabriele Blahnik, MS – Benaroya Research Institute; Anna Kus, BS – Benaroya Research Institute; Eddie James, Ph.D. – Benaroya Research Institute at Virginia Mason; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; S. Alice Long, PhD – Benaroya Research Institute
Wednesday, Jun 19
6:15 pm

W. 62 - Targeting Highly Differentiated KLRG1+ Cytotoxic T cells in Autoimmunity and Large Granular Lymphocytic Leukemia
Steven A. Greenberg, MD – Harvard Medical School; Jack Pinkus, PhD – Brigham and Women's Hospital; Clare Baecher-Allan, PhD – Brigham and Women's Hospital; Evan Thompson, PhD – Abcuro, Inc.; Stefano Gulla, PhD – Abcuro, Inc.
Wednesday, Jun 19
6:15 pm

W. 63 - Altered T cell Activation and Apoptotic Pathways Differentiate European American Autoantibody-Positive Healthy Individuals
Samantha Slight-Webb, PhD – Oklahoma Medical Research Foundation; Aleksandra Bylinkska – Oklahoma Medical Research Foundation; Miles Smith, PhD – Oklahoma Medical Research Foundation; Rufei Lu, MD, PhD – Oklahoma Medical Research Foundation; Hua Chen, PhD – Oklahoma Medical Research Foundation; Krista Bean, BS – Oklahoma Medical Research Foundation; Melissa Munroe, MD, PhD – Oklahoma Medical Research Foundation; Holden T. Maecker, PhD – Stanford University; Pj Utz, MD – Stanford University, School of Medicine; Joan Merrill, MD – Oklahoma Medical Research Foundation; Eliza Chakravarty, MD – Oklahoma Medical Research Foundation; Cristina Arriens, MD – Oklahoma Medical Research Foundation; Judith James, MD, PhD – Oklahoma Medical Research Foundation; Joel Guthridge, PhD – Oklahoma Medical Research Foundation
Wednesday, Jun 19
6:15 pm

W. 64 - Analysis of Lupus Nephritis (LN) Gene Expression Reveals Dysregulation of Pathogenic Pathways Activated within Infiltrating Cells.
Adam Labonte, Ph.D. – RILITE Research Institute; Jackson Xu – RILITE Research Institute; Sarah Heuer – RILITE Research Institute; Robert Robl – RILITE Research Institute; Prathyusha Bachali – RILITE Research Institute; Michelle Catalina, Ph.D. – RILITE Research Institute; Peter E. Lipsky, M.D. – RILITE Research Institute; Amrie C. Grammer, Ph.D. – RILITE Research Institute
Wednesday, Jun 19
6:15 pm

W. 65 - Association of FokI polymorphism in the Vitamin D Receptor Gene with Adults systemic lupus erythematosus (SLE). A Case-Control Study in Colombian Caribbean patients.
Gloria Garavito – Universidad del Norte, Barranquilla, Colombia. Universidad Simon Bolivar, Barranquilla, Colombia.; Luis Fang – Universidad del Norte, Barranquilla, Colombia.; Gustavo Aroca – Universidad del Norte, Barranquilla, Colombia. Universidad Simon Bolivar, Barranquilla, Colombia.; Antonio Iglesias – Universidad del Norte, Barranquilla, Colombia.; Ana Moreno-Woo – Universidad del Norte, Barranquilla, Colombia.; Eduardo Egea – Universidad del Norte, Barranquilla, Colombia.
Wednesday, Jun 19
6:15 pm

W. 66 - Autoimmunity Is Promoted By Dysregulated RasGRP1 Expression
Matthijs Baars – University Medical Centre Utrecht; Thera Douma – University Medical Centre Utrecht; Dimitre Simeonov – University of California San Francisco; Saikat Banerjee, PhD – University of California San Francisco; Darienne Myers, PhD – University of California San Francisco; Marijke Baltissen – Radboud University Nijmegen; Sytze de Roock, PhD – University Medical Centre Utrecht; Femke van Wijk, PhD – University Medical Centre Utrecht; Michiel Vermeulen, PhD – Radboud University Nijmegen; Alexander Marson, MD, PhD – University of California San Francisco; Jeroen Roose, PhD – University of California San Francisco; Yvonne Vercoulen, PhD – University Medical Centre Utrecht
Wednesday, Jun 19
6:15 pm

W. 67 - Autoreactivity Supports the Maintenance and Active Participation of Wild-type B cells in the Germinal Center.
Theo van den Broek – Boston Childrens's Hospital/ Harvard Medical School, Program in Cellular and Molecular Medicine; Cees E. van der Poel – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Joseph O’flynn – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Elliot Akama-Garren – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Khristina Holscher – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Michael Carroll – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine
Wednesday, Jun 19
6:15 pm

W. 68 - CD45 Antibody Drug Conjugate Safely Conditions for Transplant and Evaluation in Murine Models of Autoimmune Disease
Jennifer L. Proctor – Magenta Therapeutics; Melissa Brooks – Magenta Therapeutics; Tahirih L. Lamothe – Magenta Therapeutics; Sharon L. Hyzy – Magenta Therapeutics; Geoffrey O. Gillard, Ph.D. – Magenta Therapeutics; Sean McDonough – Magenta Therapeutics; Rahul Palchaudhuri, Ph.D. – Magenta Therapeutics; Ganapathy N. Sarma, Ph.D. – Magenta Therapeutics; Prashant Bhattarai – Magenta Therapeutics; Pranoti Sawant – Magenta Therapeutics; Brad R. Pearse, Ph.D. – Magenta Therapeutics; Charlotte F. McDonagh, Ph.D. – Magenta Therapeutics; Anthony E. Boitano, Ph.D. – Magenta Therapeutics; Michael P. Cooke, Ph.D. – Magenta Therapeutics
Wednesday, Jun 19
6:15 pm

W. 69 - Circulating follicular helper T cells are numerically reduced and exhibit a CXCR3+ phenotype in children with Down Syndrome
Georgia Fousteri – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Giorgio Ottaviano – Hospital S. Gerardo/Fondazione MBBM, University of Milano-Bicocca; Jolanda Gerosa – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Micaela Santini – Ospedale "F. Del Ponte"; Pasqualina De Leo – San Raffaele Hospital; Andrea Vecchione – San Raffaele Hospital; Tatiana Jofra – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Maurizio De Pellegrin – Department of Paediatric Orthopaedics, IRCCS San Raffaele Hospital; Massimo Agosti – Ospedale "F. Del Ponte"; Alessandro Aiuti – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget); Maddalena Marinoni – Ospedale "F. Del Ponte"; Maria Pia Cicalese – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
Wednesday, Jun 19
6:15 pm

W. 70 - Conserved human effector regulatory T cell signature is reflected in super-enhancer landscape
Gerdien Mijnheer – University Medical Centre Utrecht; Michal Mokry – University Medical Centre Utrecht; Marlot van der Wal – University Medical Centre Utrecht; Rianne Scholman – University Medical Centre Utrecht; Sytze de Roock, PhD – University Medical Centre Utrecht; Janneke Peeters – University Medical Centre Utrecht; Bas Vastert – University Medical Centre Utrecht; Leonie S. Taams – King's College London; Jorg van Loosdregt – University Medical Centre Utrecht; Femke van Wijk, PhD – University Medical Centre Utrecht
Wednesday, Jun 19
6:15 pm

W. 71 - Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire
Mohsen Khosravi-Maharlooe, MD/MSc – Columbia University; Aleksander Obradovic, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Aditya Misra – Columbia University; Keshav Motwani, Ph.D. – University of Florida; Markus Holzl, Ph.D. – Columbia University; Howard R. Seay, Ph.D. – University of Florida; Susan DeWolf, MD – Columbia University; Grace Nauman, M.A., M. Phil. – Columbia Center for Translational Immunology, Department of Medicine; Columbia University Department of Microbiology and Immunology, Columbia University Medical Center; Nichole Danzl, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Hao Wei Li, PhD – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Siu-hong Ho, Ph.D. – Columbia University; Robert Winchester, MD – Columbia University; Yufeng Shen, Ph.D. – Columbia University; Todd M. Brusko, Ph.D. – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Megan Sykes, M.D. – Columbia Center for Translational Immunology, Department of Medicine; Department of Microbiology & Immunology; Department of Surgery, Columbia University Medical Center
Wednesday, Jun 19
6:15 pm

W. 73 - Discovery of Checkpoint Agonist Antibodies for Autoimmune/Inflammatory Disease
Marilyn R. Kehry, PhD – AnaptysBio; Jean da Silva, PhD – AnaptysBio; Gerald Manorek – AnaptysBio; April Fraley – AnaptysBio; Janean Fisher – AnaptysBio; Allison Rooks – AnaptysBio; Laurence Altobell, III – AnaptysBio; Gregory Gold – AnaptysBio; Robert Morse, PhD – AnaptysBio; Margaret Marino, PhD – AnaptysBio; Jessie-Farah Fecteau, PhD – AnaptysBio; Stephen Parmley, PhD – AnaptysBio
Wednesday, Jun 19
6:15 pm

W. 74 - An optimized method for expansion and retroviral transduction of mouse regulatory T cells
May Q. Wong, BSc – University of British Columbia; Dan Wu, BSc – University of British Columbia; Jens Vent-Schmidt, BSc – University of British Columbia; Dominic A. Boardman, PhD – Department of Surgery, University of British Columbia; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia; Theodore Steiner, MD – University of British Columbia
Wednesday, Jun 19
6:15 pm

W. 75 - USP11 facilitates TGF beta signalling to augment the Treg and Th17 differentiation axis in CD4+ T cells
Roman Istomine – McGill University; Fernando Alvarez, DVM – McGill University; Ciriaco Piccirillo, Ph.D. – McGill University
Wednesday, Jun 19
6:15 pm

W. 76 - Development and clinical evaluation of a recombinant vaccine for hRSV
Jorge Soto, Phd Student – Millenium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile. Multinational FOCIS Centers of Excellence.; Nicolás M S. Gálvez Arriagada – Pontificia Universidad Católica de chile; Susan M. Bueno – Pontificia Universidad Católica de Chile; Pablo Gonzalez – Pontificia Universidad Católica de Chile; Claudia A. Riedel – Universidad Andrés Bello; Alexis M. Kalergis – Pontificia Universidad Católica de Chile
Wednesday, Jun 19
6:15 pm

W. 77 - A novel peripheral T helper subset drives extrafollicular antibody response in dengue
Asgar Ansari – National Institute of Immunology; Shilpa Sachan – National Institute of Immunology; Vinod Kumar – All India Institute of Medical Sciences; Naveet Wig – Department of Medicine, All India Institute of Medical Sciences; Alessandro Sette – La Jolla Institute for Immunology; Rita Sood – All India Institute of Medical Sciences; Daniela Weiskopf – La Jolla Institute for Immunology; Manish Soneja – Department of Medicine, All India Institute of Medical Sciences; Nimesh Gupta – National Institute of Immunology
Wednesday, Jun 19
6:15 pm

W. 78 - Age, Biological Sex and Race Affect Adaptive Immune Response to Vaccination
Inna G. Ovsyannikova, PhD – Mayo Clinic; Iana H. Haralambieva, PhD – Mayo Clinic; Richard B. Kennedy, PhD – Mayo Clinic; Gregory A. Poland, MD – Mayo Clinic
Wednesday, Jun 19
6:15 pm

W. 79 - An inflammatory status in the brain causes behavioral alterations after infection by the human respiratory syncytial virus
Karen Bohmwald – Pontifica Universidad Católica de Chile; Janyra A. Espinoza – Pontificia Universidad Católica de Chile; María C. Opazo – Universidad Andrés Bello; Ayleen Fernandez – Pontificia Universidad Católica de Chile; Felipe Gómez-Santander – Pontificia Universidad Católica de Chile; Mariana Ríos – Pontificia Universidad Católica de Chile; Eliseo A. Eugenin – Rutger University; Claudia A. Riedel – Universidad Andrés Bello; Alexis M. Kalergis – Pontificia Universidad Católica de Chile
Wednesday, Jun 19
6:15 pm

W. 80 - Bacteriophage Trigger Anti-Viral Immunity and Prevent Clearance of Bacterial Infection
Jolien Sweere, PhD – Stanford University; Jonas Van Belleghem, PhD – Stanford University; Medeea Popescu, PhD – Stanford University; Gernot Kaber, PhD – Stanford University; Christiaan DeVries, PhD – Stanford University; Gina Suh, MD – Stanford University; Robert Manasherob, PhD – Stanford University; Payton Marshall, PhD – Stanford; Swathi Balaji, PhD – Texas Children's Hospital; Sundeep Keswani, MD – Texas Children's Hospital; Patrick Secor, PhD – University of Montana; Paul Bollyky, MD, PhD – Stanford University School of Medicine
Wednesday, Jun 19
6:15 pm

W. 82 - CD4+ T Cells Specific for C. Difficile Toxins are a Marker of Patients with Active Disease
Laura Cook, PhD – University of British Columbia; May Q. Wong, BSc – University of British Columbia; Xiaojiao Wang, MSc – University of British Columbia; William D. Rees, MSc – University of British Columbia; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia; Theodore Steiner, MD – University of British Columbia
Wednesday, Jun 19
6:15 pm

W. 83 - Altered early life exposures due to immigration patterns and autoinflammatory diseases: Evaluation of the T cell immune response to commensal bacteria
Ikbel Naouar, PhD – University of Toronto; Gary Chao, PhD – University of Toronto; Julia Copeland, MSc – University of Toronto; David S Guttman, PhD – University of Toronto; Jayne Danska, PhD – The Hospital for Sick Children Research Institute - University of Toronto; Philippe Poussier, MD – Sunnybrook Health Sciences Centre - University of Toronto; Ken Croitoru, MD – Mount Sinai Hospital Zane Cohen Centre for Digestive Diseases - University of Toronto; Ahmed El-Sohemy, PhD – University of Toronto; Geoffrey Nguyen, MD, PhD – Mount Sinai Hospital; Anne Griffiths, MD – The Hospital for Sick Children - University of Toronto; Andrew Paterson, MD – The Hospital for Sick Children Research Institute - University of Toronto; John Parkinson, PhD – The Hospital for Sick Children Research Institute - University of Toronto; Kathi Wilson, PhD – University of Toronto; Jennifer Gommerman, PhD – University of Toronto
Wednesday, Jun 19
6:15 pm

W. 84 - The role of CD47 in the battlefield of Borrelia-host immune modulation in Lyme disease
Michal C. Tal, PhD – Stanford University; Maia Shoham, BSc – Stanford University; Balyn Zaro, PhD – Stanford University; Maxim Markovic, BSc – Stanford University; Irving Weissman, PhD – Stanford University
Wednesday, Jun 19
6:15 pm

W. 85 - A Cell-traceable Model of Reticular Dysgenesis in Human Hematopoietic Stem Cells Linking Metabolism and Differentiation
Wenqing Wang, PhD – Stanford University; Avni Awani, PhD – Stanford University; Lauren Reich – University of Delaware; Yusuke Nakauchi, MD, PhD – Stanford University; Daniel Thomas, MD, PhD – Stanford University; Daniel Dever, PhD – Stanford University; Matthew Porteus, MD, PhD – Stanford University; Katja Gabriele. Weinacht, MD PhD – Department of Pediatrics, Stem Cell Transplantation, at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Wednesday, Jun 19
6:15 pm

W. 86 - Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) and 22q11.2 Deletion Syndrome (DiGeorge) Cause a Thymic Hypoplasia through Distinct Molecular Mechanisms
Nicolai van Oers, PhD – UT Southwestern Medical Center; Qiumei Du, PhD – UT Southwestern Medical Center; Larry Huynh, BSc – UT Southwestern Medical Center; Fatma Coskun, BSc – UT Southwestern Medical Center; Igor Dozmorov, PhD – UT Southwestern Medical Center; Prithvi Raj, PhD – UT Southwestern Medical Center; Shaheen Khan, PhD – UT Southwestern Medical Center; Christian A. Wysocki, MD – UT Southwestern Medical Center; Mary Louise Markert, MD, PhD – Duke University; Maria Teresa de la Morena, MD – Pediatrics, U. Washington and Seattle Children's Hospital
Wednesday, Jun 19
6:15 pm

W. 87 - CRISPR/Cas9-based gene editing for IL-10/IL10RA immunodeficiency
Rosa Romano – Stanford University; Rosa Pavel-Dinu – Stanford University; Rosa Bacchetta, MD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Matthew Porteus, MD, PhD – Stanford University; Maria Grazia Roncarolo, MD PhD – Stanford University
Wednesday, Jun 19
6:15 pm

W. 88 - Diagnostic Tool to Assist Clinical Decisions for Unexplained Congenital T Cell Immunodeficiencies
Panojot Bifsha – CHU Sainte-Justine Research Center; Aurélien Colamartino – CHU Sainte-Justine Research Center, Department of Microbiology and Immunology, University of Montreal; Sung-Yun Pai – Division of Hematology-Oncology, Boston Children’s Hospital, and Department of Pediatric Oncology, Dana-Farber Cancer Institute; Mary Louise Markert – Departments of Pediatrics and Immunology, Duke University Medical Center; Nicholas Hartog – Spectrum Health/Helen DeVos Children’s Hospital, Department of Allergy and Immunology, Michigan State College of Human Medicine; Jennifer Leiding – Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, Johns Hopkins - All Children's Hospital; Elie Haddad – CHU Sainte-Justine Research Center, Department of Microbiology, Infectiology and Immunology, University of Montreal; Department of Pediatrics, University of Montreal
Wednesday, Jun 19
6:15 pm

W. 89 - Measurement of Target Cell-Specific Killing Using a Novel Highly Sensitive Bioluminescent Assay
Brock Binkowski – Promega; Christopher Eggers – Promega; Aileen Paguio – Promega; Pete Stecha – Promega; Braeden Butler – Promega; Jey Cheng – Promega; Vanessa Ott – Promega; Mei Cong – Promega; Frank Fan – Promega
Wednesday, Jun 19
6:15 pm

W. 90 - PD-1H (VISTA) induces immune evasion in acute myeloid leukemia
Tae Kon Kim, MD, PhD – Yale University; Xue Han, PhD – Yale University; Esten Vandsemb, BS – Norwegian University of Science and Technology; Jun Wang, PhD – Yale University; Qi Wang, PhD – Beth Israel Deaconess Med Center; Jian-Ping Zhang, PhD – Yale University; Ti Badri, PhD – Yale University; Lieping Chen, MD, PhD – Yale University
Wednesday, Jun 19
6:15 pm

W. 91 - Switching CAR Drivers: from T to NK Cells
William Lemieux – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Aurelien Colamartino – CHU Sainte-Justine and University of Montreal; Panojot Bifsha – CHU Sainte-Justine Research Center; Simon Nicoletti – INSERM U1163 and CNRS ERL 8254, Medicine Faculty, Paris Descartes University, Necker Hospital; Joaquin Sanz Remon – CHU Sainte-Justine and University of Montreal; Hugo Romero – CHU Sainte-Justine; Silvia Selleri, PhD – CHU Sainte-Justine Research Center, Montreal, QC, Canada; Department of Microbiology, Infectiology and Immunology, University of Montreal; Kathie Beland – CHU Sainte-Justine; Melanie Guiot – UPMC Paris 6 and CIRI – International Center for Infectiology Research, Team EVIR; Renee Dicaire – CHU Sainte-Justine; Luis Barreiro – The University of Chicago; Els Verhoyen – CNRS, UMR5308 and Université Côte d’Azur, INSERM, C3M; Elie Haddad – CHU Sainte-Justine Research Center, Department of Microbiology, Infectiology and Immunology, University of Montreal; Department of Pediatrics, University of Montreal
Wednesday, Jun 19
6:15 pm

W. 93 - Teaching an Old Assay New Tricks. A New Automated Cell Population Discovery Method Identifies Common Baseline Predictors of Outcome Across Cancer Immunotherapy Trials.
Greg Finak, PhD – Fred Hutchinson Cancer Research Center; Evan Greene, PhD – Fred Hutchinson Cancer Research Center; Raphael Gottardo, PhD – Fred Hutchinson Cancer Research Center
Wednesday, Jun 19
6:15 pm

W. 94 - The Impact of Pharmacological Targeting of Glucose Metabolism with 3-Bromopyruvate on Immunogenic Cell Death in Breast Cancer Cells
Kevin Lang, PhD – Florida Atlantic University; James Hartmann, PhD – Florida Atlantic University; Rachael Berrie – Florida Atlantic University; Luis Quintero – Florida Atlantic University; Patricia Keating, PhD – Florida Atlantic University
Wednesday, Jun 19
6:15 pm

W. 95 - The rational design of synthetic long peptides using a universal helper epitope can improve the therapeutic effects of neoantigen vaccines
Adam Swartz, PhD – Duke University; Katherine Riccione, PhD – Duke University; Kendra Congdon, PhD – Duke University; Luis Sanchez-Perez, PhD – Duke University; Smita Nair, PhD – Duke University; John Sampson, MD, PhD – Duke University
Wednesday, Jun 19
6:15 pm

W. 96 - TIGIT+TRDV1+ Expressing Tumours have a Transcriptomic Signature with Positive Prognostic Value
Cathriona Foley, PhD. – Cork Institute of Technology; Michael Wilkinson, Dr. – School of Medicine, Catherine McAuley Research Centre, Mater Misericordiae University Hospital, Eccles Street, Dublin; Fiona Martyn, MD. PhD. – Merrion Fertility Clinic, National Maternity Hospital, Dublin; Joanna Tilley – School of Biochemistry and Immunology, Trinity College, Dublin; Louise Glover, PhD. – Merrion Fertility Clinic, National Maternity Hospital, Dublin; Karsten Hokamp, PhD. – Trinity College, Dublin; Donal Brennan, MD. PhD. – School of Medicine, Catherine McAuley Research Centre, Mater Misericordiae University Hospital, Eccles Street, Dublin; Lydia Lynch, PhD – Deptartment of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
Wednesday, Jun 19
6:15 pm

W. 97 - Tumor-associated M2 macrophages may adopt mesothelial precursor cell phenotypes to initiate mesothelioma tumorigenesis in mice
Licun Wu – University Health Network; Mikihiro Kohno – University Health Network; Mei-Lin Chan – University Health Network; Junichi Murakami – University Health Network; Hana Yun – University Health Network; Bill Duong – University of Toronto; Brenda Green – University of Toronto; Zongjie Wang – University of Toronto; Reza Mohanmodi – University Health Network; Fernando José Peña – University of Toronto; Yuxiao Zhou – University of Toronto; Shana Kelley – University of Toronto; Yidan Zhao – University Health Network; Emanuela Felley-Bosco – University of Zurich; Marc de Perrot – Universty Health Network
Wednesday, Jun 19
6:15 pm

W. 99 - Genetic Risk for Skin Autoimmunity Impacts the Safety and Efficacy of Immune Checkpoint Blockade in Urothelial Carcinoma
Zia Khan, PhD – Genentech; Scott Chandler, MD PhD – Genentech / Roche; Matthew Albert, MD PhD – Genentech
Wednesday, Jun 19
6:15 pm

W. 100 - Context-Specific Regulation of Monocyte Surface and Soluble IL7R Expression by a Genetic Risk Allele
Hussein Al-Mossawi, BA, MA (Oxon), BMBCh, MRCP, DPhil – University of Oxford; Nicole Yager, BSc DPhil – University of Oxford; Chelsea Taylor, BSc – University of Oxford; Sara Danielli, BSc – University of Oxford; Elise Mahe, BSc PhD – University of Oxford; Paul Bowness, BSc MA DPhil FRCP – University of Oxford; Benjamin Fairfax, BSc PhD MRCP – University of Oxford
Wednesday, Jun 19
6:15 pm

W. 101 - Leukotrienes and resolvins induced by HMGB1 and HMGB1 plus C1q reciprocally regulate IRF5
Myoungsun Son, PhD – Feinstein Institute for Medical Research; Tianye Liu – Feinstein Institute for Medical Research; Alec Xiang – Feinstein Institute for Medical Research; Travis Peng – Feinstein Institute for Medical Research; Amanda Doran, MD – Columbia University Medical Center; Kevin Tracey, MD – Feinstein Institute for Medical Research; Betsy Barnes, PhD – Feinstein Institute for Medical Research; Ira Tabas, MD PhD – Columbia University Medical Center; Betty Diamond, MD – Feinstein Institute for Medical Research
Wednesday, Jun 19
6:15 pm

W. 102 - Myo-/Fibroblast MyD88-Mediated Signaling Regulates Inflammatory Responses in the Colon by Suppressing Influx of Inflammatory Macrophages
Gabriela Uribe, BS – University of Texas Medical Branch; Kamil Khanipov, PhD – University of Texas Medical Branch; Georgiy Golovko, PhD – University of Texas Medical Branch; Romain Villeger, PhD – University of Texas Medical Branch; Carl Grim, BS – University of Texas Medical Branch; JIng He, MD – University of Texas Medical Branch; Ellen Beswick, PhD – University of Utah; Don Powell, MD – University of Texas Medical Branch; Iryna Pinchuk, PhD – PennState Health
Wednesday, Jun 19
6:15 pm

W. 103 - Physical Activity at Lower Intensities Produces a Tolerogenic Effect and Reduces Localized IL-1β in a Murine Model of Gout in Circulating Neutrophils
Kyle A. Jablonski, MS – The Ohio State University; Paul Consiglio – The Ohio State University Division of Pulmonary, Allergy, Critical Care and Sleep Medicine; Caitlin Henry – The Ohio State University Wexner Medical Center Division of Immunology; Emily Schwarz – The Ohio State University Wexner Medical Center Division of Immunology; Peter Harb – The Ohio State University Wexner Medical Center Division of Immunology; Ifeoma Okafor, MPH – The Ohio State University Wexner Medical Center Division of Immunology; Anasuya Sarkar, PhD – The Ohio State University Wexner Medical Center Division of Pulmonary, Allergy, Critical Care and Sleep Medicine; Wael Jarjour, MD – The Ohio State University Wexner Medical Center Division of Immunology; Naomi Schlesinger, MD – Robert Wood Johnson University Hospital; Nicholas Young, PhD – The Ohio State University Wexner Medical Center Division of Immunology
Wednesday, Jun 19
6:15 pm

W. 104 - Profiling of 1,600 novel natural product-based compounds in human primary cell-based phenotypic assays
Jamil Aarbiou, PhD – Charles River Laboratories; Krista Ouwehand, PhD – Charles River Laboratories; Julie Vann – Charles River Laboratories; David F. Fischer, PhD – Charles River Laboratories; Blandine Mille-Baker, PhD – Charles River Laboratories; Jeroen DeGroot, PhD – Charles River Laboratories
Wednesday, Jun 19
6:15 pm

W. 105 - Recombinant Fragment of Human Surfactant Protein D (rfhSP-D) Interacts with GRP78: Potential Role in SP-D Induced Anti- Prostate Cancer Activity
Gargi Kunal. Thakur, Masters in Medical Genetics, Pursuing PhD in Biotechnology – Department of Innate Immunity, ICMR- National Institute for Research in Reproductive Health; Gajanan Sathe – NIMHANS-IOB; Indra Kundu – Biomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health; Poonam Gautam – National Institute of Pathology, ICMR; Susan Idicula-Thomas – Biomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health; Ravi Sirdeshmukh – Institue of Bioinformatics, ITPL; Taruna Madan – Department of Innate Immunity, ICMR- National Institute for Research in Reproductive Health
Wednesday, Jun 19
6:15 pm

W. 106 - Role of XCR1+ DC in cross-presentation of antigen in XCR1-RYDL mice
Fatima Manzoor – Sanofi; (Laura) Ashley Aronow – Sanofi; Natalia Malkova – Sanofi; Timothy Soos – Sanofi; Hakju Kwon – Sanofi
Wednesday, Jun 19
6:15 pm

W. 107 - Single-cell Multiplex Proteomics Identifies Functional Differences between Circulating CD14+ CD16- and CD14+CD16+ Monocytes in Patients with Frontotemporal degeneration, Providing Basis for Understanding Disease Progression
Patrick Paczkowski, PhD – IsoPlexis Corporation; Sean Mackay, MS – IsoPlexis Corporation; Brianna Flynn, MS – IsoPlexis Corporation; Peter Ljubenkov, MD – UCSF Memory and Aging Center, Department of Neurology; Jing Zhou, MD, PhD – IsoPlexis Corporation
Wednesday, Jun 19
6:15 pm

W. 108 - The calcium response of human monocytes to CCL2 increases in aging
Bruno de Jesús Arellado-Cruz, Bs – Universidad Veracruzana; Maria de los Angeles. Vázquez Prieto, Clinic Chemistry – Universidad Veracruzana; Nilda Belén Fernández-Eufrasio, MD – Universidad Veracruzana; Adriana Sumoza-Toledo, PhD – Universidad Veracruzana
Wednesday, Jun 19
6:15 pm

W. 109 - Extracellular Cold-inducible RNA-binding Protein Enhances Murine Pulmonary Fibrosis
Siavash Bolourani, MD – The Feinstein Institute for Medical Research; Monowar Aziz, PHD – The Feinstein Institute for Medical Research; Max Brenner, MD-PHD – The Feinstein Institute for Medical Research; Ping Wang, MD – The Feinstein Institute for Medical Research
Wednesday, Jun 19
6:15 pm

W. 110 - Preliminary mechanistic studies of regulatory dendritic cell (DCreg) cell infusion in living donor liver transplant recipients
Camila Macedo, MD – University of Pittsburgh, Department of Surgery; Alan Zahorchak, MS – University of Pittsburgh, Department of Surgery; Helong Dai, MD – University of Pittsburgh, Department of Surgery; Abhinav Humar, MD – University of Pittsburgh, Department of Surgery; Fadi Lakkis, MD – University of Pittsburgh, Department of Surgery; Mindi Styn, PhD – University of Pittsburgh, Department of Surgery; Angus Thomson, PhD – University of Pittsburgh, Department of Surgery; Diana Metes, MD – University of Pittsburgh, Department of Surgery
Wednesday, Jun 19
6:15 pm

W. 111 - Early CXCR5+PD1+ICOS+ circulating T follicular helper cells are associated with de novo donor-specific anti-HLA antibodies after renal transplantation
Richard Danger – CRTI UMR1064, INSERM, Université de Nantes; Mélanie Chesneau – CRTI UMR1064, INSERM, Université de Nantes; Florent Delbos, PhD – Laboratoire HLA, Etablissement Français du Sang Centre Pays-de-le-Loire; Sabine Lebot, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Clarisse Kerleau – Centre Hospitalier Universitaire de Nantes; Alexis Chenouard, MD, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Simon Ville, MD, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Nicolas Degauque, PhD – CRTI UMR1064, INSERM, Université de Nantes; Sophie Conchon – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Anne Cesbron – EFS Pays de La Loire; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Wednesday, Jun 19
6:15 pm

W. 112 - Enhanced myocardiac autophagy induces heart transplant tolerance by blockade of BET signaling pathway
Weihua Gong – zhejiang university; Juntao Chen – zhejiang university
Wednesday, Jun 19
6:15 pm

W. 113 - IL-6 Receptor Expression on T Cells Is Needed for the Development of Donor-Specific Antibodies Towards Vascular Allografts
Ashani Montgomery, BSc – Simon Fraser University; Kevin Rey, BSc – Simon Fraser University; Winnie Enns, BSc – Simon Fraser University; Naomi Giesbrecht, BSc – Simon Fraser University; Catherine Cheneval, BSc – Simon Fraser University; Jonathan Choy, PhD – Simon Fraser University
Wednesday, Jun 19
6:15 pm

W. 114 - Interleukin-7 receptor blockade by a human anti-CD127 monoclonal antibody in non-human primate kidney transplantation
Hoa L. Mai, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Thi Van Ha Nguyen, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Julien Branchereau, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, Service d'Urologie, CHU de Nantes; Nicolas Poirier, PhD – OSE Immunotherapeutics; Karine Renaudin, MD – Service d'anapathologie CHU Hotel Dieu Nantes, Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, Nantes, France; Caroline Mary, PhD – OSE Immunotherapeutics; Lyssia Belarif, PhD – OSE Immunotherapeutics; David Minault – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Jeremy Hervouet – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Stéphanie Bernadet, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Jean-Paul Soulillou, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Bernard Vanhove, PhD – OSE Immunotherapeutics; Gilles Blancho, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Wednesday, Jun 19
6:15 pm

W. 115 - Metabolic pathways regulate the migration of TEMRA CD8 to inflammatory site
Tra My Doan Ngoc – CRTI UMR1064, INSERM, Université de Nantes; Gaelle Tilly – CRTI UMR1064, INSERM, Université de Nantes; Sarah Bruneau, PhD – CRTI UMR1064, INSERM, Université de Nantes; Alexandre Glemain – CRTI UMR1064, INSERM, Université de Nantes; Pierrick Guerif – Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Claire Pecqueur – Centre de Recherche en Cancérologie et Immunologie Nantes-Angers, UMR1232 INSERM, Université de Nantes; Nicolas Degauque, PhD – CRTI UMR1064, INSERM, Université de Nantes
Wednesday, Jun 19
6:15 pm

W. 116 - Positive Selection of a Human-Restricted TCR in a Swine Thymus in a TCR Transgenic Humanized Mouse Model
Grace Nauman, M.A., M. Phil. – Columbia Center for Translational Immunology, Department of Medicine; Columbia University Department of Microbiology and Immunology, Columbia University Medical Center; Chiara Borsotti, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Nichole Danzl, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Mohsen Khosravi-Maharlooei, M.D., Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Hao Wei Li, PhD – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Estefania Chavez – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Yong-Guang Yang, M.D., Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Megan Sykes, M.D. – Columbia Center for Translational Immunology, Department of Medicine; Department of Microbiology & Immunology; Department of Surgery, Columbia University Medical Center
Wednesday, Jun 19
6:15 pm

W. 117 - The role of circular RNA FSCN1 in dendritic cell mediated immunomodulation
Bowen Wang – Western University; Cuilin University – Western University; Yale Su – Western University; Dana O'Brien – Western University; Xiufen Zheng, PhD – Western University
Wednesday, Jun 19
6:15 pm

W. 118 - Time-dependent lymphocyte count after transplantation is associated with higher risk of graft failure and death
Amaury Dujardin, Resident – Centre Hospitalier Universitaire de Nantes; Marine Lorent – Centre d’Investigation Clinique en Biothérapie, Labex IGO; Christophe Legendre, MD, PhD – Kidney Transplant Center, Necker University Hospital; Alexandre Loupy, MD, PhD – Kidney Transplant Center, Necker University Hospital; Clarisse Kerleau – Centre Hospitalier Universitaire de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes
Wednesday, Jun 19
6:15 pm

W. 119 - Tissue Derived Fetal T Cells Secrete Labor Cytokines in Response to Antigen at the Fetal-Maternal Interface
Jessica Toothaker, BA – University of Pittsburgh; Collin McCourt – UPMC Childrens Hospital of Pittsburgh; Stephanie Stras, BA – UPMC Childrens Hospital of Pittsburgh; Oluwabunmi Olaloye, MD – UPMC Childrens Hospital of Pittsburgh; Liza Konnikova, MD, PhD – UPMC Childrens Hospital of Pittsburgh
Wednesday, Jun 19
6:15 pm

W. 120 - Intravenous Immunoglobulin modulates blood monocyte subsets in women with recurrent gestational failure of inflammatory cause
Lorena Valdeolivas-De Opazo – Hospital Clínico San Carlos; Alejandra Comins-Boo – Hospital Clínico San Carlos; Ángeles Domínguez-Soto – Centro de Investigaciones Biológicas; Lidia Fernández-Paredes – Hospital Clínico San Carlos; Elena Carrillo de Albornoz – Hospital Ruber Internacional; Elena Meliá – Hospital Ruber Internacional; Victoria Verdú – Ginefiv; Fernando Pérez-Pla – Universidad de Cantabria; Edgard Rodríguez-Frías – Hospital Clínico San Carlos; Miguel Fernández-Arquero – Hospital Clínico San Carlos; Ángel L. Corbí – Centro de Investigaciones Biológicas; Silvia Sanchez-Ramon – Hospital Clinico San Carlos
Wednesday, Jun 19
6:15 pm

W. 121 - Early expansion of TEMRA CD8 with innate-like function identifies kidney transplant recipients at high-risk of graft failure
Lola Jacquemont, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Gaelle Tilly – CRTI UMR1064, INSERM, Université de Nantes; Michelle Yap, PhD – CRTI UMR1064, INSERM, Université de Nantes; Tra My Doan Ngoc – CRTI UMR1064, INSERM, Université de Nantes; Richard Danger – CRTI UMR1064, INSERM, Université de Nantes; Pierrick Guerif – Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes; Florent Delbos, PhD – Laboratoire HLA, Etablissement Français du Sang Centre Pays-de-le-Loire; Bernard Martinet – CRTI UMR1064, INSERM, Université de Nantes; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Yohann Foucher, PhD – SPHERE UMR1246, INSERM, Université de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Nicolas Degauque, PhD – CRTI UMR1064, INSERM, Université de Nantes
Wednesday, Jun 19
6:15 pm

W. 122 - Generation of CD8+ and CD4+ Regulatory T Cells from Human Pluripotent Stem Cells
Lea Flippe – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; Anne Gaignerie – iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Séverine Bézie – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Ignacio Anegon – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Laurent David – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France, iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Carole Guillonneau – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO
Wednesday, Jun 19
6:15 pm

W. 123 - A TCR Sequencing Approach to Study the Dynamics of Alloreactive and Autoreactive T Cells Following Liver Transplantation for Autoimmune Liver Disease
Brittany A. Shonts, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Mercedes Martinez, M.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Elias Spyrou, M.D./Ph.D. – Columbia Center for Translational Immunology, Division of Digestive and Liver Diseases, Columbia University Medical Center; Thomas Savage, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Aleksander Obradovic, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Shana M. Coley, M.D./Ph.D. – Columbia Center for Translational Immunology, Department of Pathology & Cell Biology, Columbia University Medical Center; Sai ping Lau, M.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Suxio Yang, M.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Kortney Rogers, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Kryscilla J. Yang, M.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Christopher Parks, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Megan Sykes, M.D. – Columbia Center for Translational Immunology, Department of Medicine; Department of Microbiology & Immunology; Department of Surgery, Columbia University Medical Center
Wednesday, Jun 19
6:15 pm

W. 124 - Blood CD9+ B Cell, a Biomarker of Brochiolitis Obliterens Syndrome After Lung Transplantation
Carole Brosseau – Centre de Recherche en Transplantation et Immunologie; Richard Danger – CRTI UMR1064, INSERM, Université de Nantes; Maxim Durand – Center for Research in Transplantation and Immunology - INSERM UMR1064 - Nantes; Eugénie Durand – Center for Research in Transplantation and Immunology - INSERM UMR1064 - Nantes; Aurore Foureau – CHU Nantes; Antoine Magnan – CHU Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Wednesday, Jun 19
6:15 pm

W. 125 - BMP signaling pathway modulation promotes tolerance in GvHD and prevents colitis.
Magdiel Pérez-Cruz, PhD – Stanford University; Bettina Iliopoulou, PhD – Stanford University; Katie Hsu, MS – Stanford University; Hsin-Hsu Wu, MD – Stanford University; Tom Erkers, PhD – Stanford University; Kavya Swaminathan, PhD – Stanford University; Sai-Wen Tang, PhD – Stanford University; Wendy Pang, PhD – Stanford University; Neeraja Kambham, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine; Rosemarie H. Dekruyff, PhD – Stanford University; Gordon J. Freeman, PhD – Dana-Farber Cancer Institute; Everett Meyer, MD, PhD – Stanford University
Wednesday, Jun 19
6:15 pm

W. 126 - Cellular Desialation Promotes Xenogeneic Neutrophil-Endothelial Adhesion via Galectin-3
Benjamin Cerel, BS – MGH and Harvard Medical School; Beth French, PhD – University of Maryland Baltimore; Christopher Laird, MD – University of Maryland Baltimore; Xiangfei Cheng, PhD – University of Maryland Baltimore; Lars Burdorf, MD – MGH and Harvard Medical School; Richard Pierson, MD – MGH and Harvard Medical School; Agnes Azimzadeh, PhD – MGH and Harvard Medical School
Wednesday, Jun 19
6:15 pm

W. 127 - Expansion of Highly Purified Functional Alloantigen-specific Tr1 Cells for Therapeutic use in Kidney Transplanted patients
Nadyeli Linares – INSTITUTO DE INVESTIGACIONES BIOMEDICAS, UNAM; Saul Arteaga – Instituto de Investigaciones Biomédicas, UNAM; Arimelek Cortes-Hernandez – Instituto de Investigaciones Biomédicas, UNAM; Evelyn K Alvarez-Salazar – Instituto de Investigaciones Biomédicas, UNAM; Josefina Alberú – Unidad de Trasplantes. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Gloria Soldevila – Instituto de Investigaciones Biomédicas, Universidad Nacional Autonoma de Mexico
Wednesday, Jun 19
6:15 pm

W. 129 - Immunologic Impact of Tocilizumab Treatment in Kidney Transplant Recipients with Allograft Inflammation
Joey Leung – University of California San Francisco; Qizhi Tang, Ph.D. – University of California San Francisco; Sindhu Chandran, MBBS – University of California San Francisco; Crystal Hu – University of California San Francisco; Flavio Vincenti, MD – University of California San Francisco
Wednesday, Jun 19
6:15 pm

W. 130 - Immunoprotection of skin Allografts with Indoleamine 2,3-dioxygenase
Mohammadreza Pakyari, MD; PhD – Harvard University
Wednesday, Jun 19
6:15 pm

W. 131 - Immunosuppressant-resistant cytomegalovirus-specific T cells for advanced adoptive T-cell therapy in immunosuppressed patients
Leila Amini – Charité Universitaetsmedizin Berlin; Dimitrios Wagner, medical student – Charité Universitaetsmedizin Berlin; Uta Rössler, M.Sc. – Charité Universitaetsmedizin Berlin; Uwe Kornak, Ph.D. – Institute of Human and Medical Genetics; Hans-Dieter Volk, M.D./Ph.D. – Charité Universitaetsmedizin Berlin; Petra Reinke – Charité Universitaetsmedizin Berlin; Michael Schmueck-Henneresse, Ph.D. – Charité Universitaetsmedizin Berlin
Wednesday, Jun 19
6:15 pm

W. 132 - In Situ B Cell Activation and Selection in Human Renal Allograft Rejection
Yuta Asano – Department of Medicine, Section of Rheumatology and The Knapp Center for Lupus and Immunology Research, The University of Chicago, Chicago, IL, USA; Joe Daccache – Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; Dharmendra Jain, PhD – Section of Transplant, Department of Surgery, The University of Chicago, Chicago, IL, USA; Anita Chong, PhD – Section of Transplant, Department of Surgery, The University of Chicago, Chicago, IL, USA; Shiv Pillai, MD PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Marcus Clark, MD – Department of Medicine, Section of Rheumatology and The Knapp Center for Lupus and Immunology Research, The University of Chicago, Chicago, IL, USA
Wednesday, Jun 19
6:15 pm

W. 133 - microRNA-191 regulates T-cell clonal expansion during graft-versus-host disease
Chuanfeng Xiong, MD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Wei Huang, MD.PHD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Xiaoli Nie, MD.PHD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Ying Huang, MD.PHD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Yiqun Jiao, MD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Yujing Zou, PHD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Charles Huang – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Emilio Feijoo – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Dong Pan, PHD – Department of Dermatology, Duke University Medical Center; Nelson J Chao, MD.MBA – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center; Qijing Li, PHD – Department of Immunology, Duke University Medical Center; Benny J Chen, MD – Division of Hematologic Malignancies and Cellular Therapy/BMT, Duke University Medical Center
Wednesday, Jun 19
6:15 pm

W. 134 - Targeting the adaptive and innate immune barriers to cell transplantation using gene editing in human pluripotent stem cells
Xiao Han – Harvard University; Torsten B. Meissner – Harvard University; Jack L. Strominger – Harvard University; Chad A. Cowan – Harvard University
Wednesday, Jun 19
6:15 pm

W. 135 - The value of a rapid test of human regulatory T cell function needs to be revised
Desiree J. Wendering, M.Sc. Molecular Medicine – Insitute for Medical Immunology, Charite; Leila Amini – Charité Universitaetsmedizin Berlin; Stephan Schlickeiser, PhD – Charité Universitätsmedizin, Institute for Medical Immunology; Petra Reinke – Charité Universitaetsmedizin Berlin; Hans-Dieter Volk, M.D./Ph.D. – Charité Universitaetsmedizin Berlin; Michael Schmueck-Henneresse, Ph.D. – Charité Universitaetsmedizin Berlin
Wednesday, Jun 19
6:15 pm

W. 136 - Unique and Specific Proteobacteria Diversity in Urinary Microbiota of Tolerant Kidney Transplanted Recipients
Luc Colas – CHU de Nantes ; Inserm; Emmanuel Mongodin – emongodin@som.umaryland.edu; Emmanuel Montassier – CHU de Nantes; Mélanie Chesneau – CRTI UMR1064, INSERM, Université de Nantes; Pierrick Guerrif – CHU de Nantes; Lauren Hittle – University of Maryland School of Medicine; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Jonathan Bromberg – University of Maryland School of Medicine; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Thursday, Jun 20
6:15 pm

Exhibit and Poster Reception (authors present)
Location: Salon E, 4th Floor
Sponsored By:
Thursday, Jun 20
6:15 pm

H. 1 - Natural Tr1-like Cells Do Not Confer Long-Term Tolerogenic Memory
Carlos O. Medina, BS – Stanford University School of Medicine; Koshika Yadava, PhD – Stanford University School of Medicine; Heather Ishak, BS, MS – Stanford University School of Medicine; Irina Gurevich, PhD – Stanford University School of Medicine; Hedwich Kuipers, PhD – Stanford University School of Medicine; Elya Shamskhou, BS – Stanford University School of Medicine; Ievgen Koliesnik, PhD – Stanford University School of Medicine; James J. Moon, PhD – Harvard University; Casey Weaver, PhD – University of Alabama School of Medicine; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Paul Bollyky, MD, PhD – Stanford University School of Medicine
Thursday, Jun 20
6:15 pm

H. 2 - Phospholipid Phosphatase 6 Selectively Regulates Phagocyte Function and Immune Responses
Thayse R. Bruggemann – Brigham and Women's Hospital and Harvard Medical School; Nandini Krishnamoorthy – Brigham and Women's Hospital and Harvard Medical School; Melody G. Duvall – Brigham and Women's Hospital and Harvard Medical School; Raja-Elie E. Abdulnour – Brigham and Women's Hospital and Harvard Medical School; Bruce D. Levy – Brigham and Women's Hospital and Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 3 - Randomized Controlled Phase 2a Study Results Using Anti IL-33 in Food Allergy
Cherie Liu – Stanford University; R. Sharon Chinthrajah, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Andrew Long, PharmD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Shu-Chen Lyu, MSc – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Marco Londei, MD – AnaptysBio; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Thursday, Jun 20
6:15 pm

H. 4 - Robustness of the Evidence Supporting the Association Between Air Pollution and Immune-based Diseases
George Markozannes – University of Ioannina School of Medicine; Evangelos Rizos – University Hospital of Ioannina, European University of Cyprus; Ourania Sintosi – University of Ioannina Department of Physics; Evangelia Ntzani – University of Ioannina School of Medicine
Thursday, Jun 20
6:15 pm

H. 5 - Toward fully leveraging the capabilities of basophil activation test in clinical research through workflow simplification and standardization
Jean-Marc Busnel, PhD – Beckman Coulter Life Sciences
Thursday, Jun 20
6:15 pm

H. 6 - Understanding the pathogenesis of pulmonary fibrosis using the Fra2-Tg model
Hamid Mattoo, Ph.D. – Sanofi/US; Ethan Xu, Ph.D. – Sanofi/US; Robert Resnick – Sanofi/US; Tai-he Xia, Ph.D. – Sanofi/US; Erica Herzog, MD, Ph.D. – Yale School of Medicine; Paul Bryce, Ph.D. – Sanofi/US; Arun Subramaniam, Ph.D. – Sanofi/US
Thursday, Jun 20
6:15 pm

H. 7 - Gastrointestinal Eosinophilia Is Present in Oral Immunotherapy Subjects With IgE-Mediated Peanut Allergy at Baseline
R. Sharon Chinthrajah, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Benjamin L. Wright, MD – Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Division of Pulmonology, Phoenix Children's Hospital; Nielsen Q. Fernandez-Becker, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Neeraja Kambham, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine; Natasha Purington, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Dana Tupa, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Wenming Zhang, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Matthew A. Rank, MD – Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Division of Pulmonology, Phoenix Children's Hospital; Hirohito Kita, MD – Division of Allergic Diseases, Internal Medicine, Mayo Clinic, Rochester; Kelly P. Shim – Division of Pulmonology, Phoenix Children's Hospital, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona; Bryan J. Bunning – Stanford University - Sean N Parker Center for Allergy and Asthma ResearchStanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Alfred D. Doyle, MD – Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona; Elizabeth A. Jacobsen, PhD – Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona,; Scott D. Boyd, MD – Department of Pathology, Stanford University School of Medicine, Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Mindy Tsai, DMSc – Department of Pathology, Stanford University School of Medicine; Holden T. Maecker, PhD – Stanford University; Monali Manohar, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Stephen J. Galli, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine, Department of Microbiology and Immunology, Stanford University School of Medicine; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Thursday, Jun 20
6:15 pm

H. 8 - Diminished Long-Term Outcome in Large Phase 2 Study of Peanut Immunotherapy
R. Sharon Chinthrajah, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Natasha Purington, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Sandra Andorf, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Andrew Long, PharmD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Katherine L. O’Laughlin, MN – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Shu-Chen Lyu, MSc – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Monali Manohar, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Scott D. Boyd, MD – Department of Pathology, Stanford University School of Medicine, Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Robert Tibshirani, PhD – Department of Biomedical Data Sciences, Stanford University, Department of Statistics, Stanford University; Holden T. Maecker, PhD – Stanford University; Marshall Plaut, MD – National Institute of Allergy and Infectious Diseases; Kaori Mukai, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine, Stanford; Mindy Tsai, DMSc – Department of Pathology, Stanford University School of Medicine; Manisha Desai, PhD – Quantitative Sciences Unit, Stanford University School of Medicine; Stephen J. Galli, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine, Department of Microbiology and Immunology, Stanford University School of Medicine; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Thursday, Jun 20
6:15 pm

H. 9 - Effective Treatment of Experimental Asthma by Lung-restricted Inhibition of Janus Kinase 1
Nico Ghilardi – Genentech
Thursday, Jun 20
6:15 pm

H. 10 - ‘Older’ T cell and B cell compartments in patients with Parkinson’s Disease
Rui Li, MD, PhD – Perelman School of Medicine, University of Pennsylvania; Laura Baratta – University of Pennsylvania; Maria Ortiz – University of Pennsylvania; Sushma Narayan – Columbia University; Roy Alcalay, MD – Columbia University; Thomas Tropea, MD – University of Pennsylvania; Alice ChenPlotkin, MD – University of Pennsylvania; Amit Bar-Or, MD – Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania
Thursday, Jun 20
6:15 pm

H. 11 - Anti-inflammatory B cell shift induced by Bruton’s Tyrosine Kinase (BTK) inhibition
Rui Li, MD, PhD – Perelman School of Medicine, University of Pennsylvania; Hao Tang, Ph.D – MS Research Unit, Biogen; Bin Ma, Ph.D – MS Research Unit, Biogen; Hopkins Brian – MS Research Unit, Biogen; Michaël Mingueneau, Ph.D. – Biogen; Amit Bar-Or, MD – Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania
Thursday, Jun 20
6:15 pm

H. 12 - B cell:Myeloid cell interaction and contribution to the CNS compartmentalized inflammation of Multiple Sclerosis
Hanane Touil, PhD – The University of Pennsylvania; Rui Li, MD, PhD – Perelman School of Medicine, University of Pennsylvania; Leah Zuroff – University of Pennsylvania; Craig Moore, PhD – Memorial University of Newfoundland and Labrador; Luke Healy, PhD – McGill University; Francesca Cignarella, PhD – Washington University; Laura Piccio, MD, PhD – Washington University; Samuel Ludwin, MD, PhD – Queens University; Jennifer Gommerman, PhD – University of Toronto; Alexandre Prat, MD, PhD – Université de Montréal; Jack Antel, MD, PhD – McGill University; Amit Bar-Or, MD – Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania
Thursday, Jun 20
6:15 pm

H. 13 - B cells regulate CD8+ MAIT cell effector functions: implications to multiple sclerosis
Ayman Rezk, BSc – Perelman School of Medicine, University of Pennsylvania; Rui Li, PhD – University of Pennsylvania; Amit Bar-Or, MD – Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania
Thursday, Jun 20
6:15 pm

H. 14 - Comparison of Immunoprofiling and Gene Expression Analysis in Benign and Secondary Progressive Multiple Sclerosis
Yang Mao-Draayer, MD PhD – University of Michigan; Qi Wu, PhD – U Michigan; Qin Wang, PhD – U Michigan; Steve Lundy, PhD – U Michigan
Thursday, Jun 20
6:15 pm

H. 15 - CysLTR2 Signaling on T cells Is Required For Experimental Autoimmune Encephalomyelitis
Markus A. Schramm, M.D. – Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston; Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Germany; Norio Chihara, M.D., Ph.D. – Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston; Karen O. Dixon, Ph.D. – Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston; Yoshihide Kanaoka, M.D., Ph.D. – Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston; K. Frank Austen, M.D. – Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston; Vijay K. Kuchroo, D.V.M., Ph.D. – Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston
Thursday, Jun 20
6:15 pm

H. 16 - Dimethyl Fumarate Therapy Reduces the Frequency of Memory T cells and the Potential of CNS Trans-migration in Patients with Multiple Sclerosis
RIkke H. Hansen – Danish Multiple Sclerosis Center, department of neurology, Copenhagen university hospital, Rigshospitalet; Helene Højsgaard Chow – Danish multiple sclerosis center, department of neurology, copenhagen university hospital, rigshospitalet; Jeppe Romme Christensen – Danish multiple sclerosis center, department of neurology, copenhagen university hospital, rigshospitalet; Finn Sellebjerg – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet; Marina Rode von Essen – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet
Thursday, Jun 20
6:15 pm

H. 17 - Eomes+ Th cells: A crucial biomarker for Secondary Progressive Multiple Sclerosis (SPMS) disease status
Ben JE. Raveney, PhD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Wakiro Sato, MD PhD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Daiki Takewaki, MD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Youwei Lin, MD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP); Tomoko Okamoto, MD – Department of Neurology, National Center of Neurology and Psychiatry (NCNP); Manabu Araki, MD – Department of Neurology, National Center of Neurology and Psychiatry (NCNP); Shinji Oki, PhD – Department of Immunology, National Center of Neurology and Psychiatry (NCNP)
Thursday, Jun 20
6:15 pm

H. 18 - Follicular helper T cells may promote T-B interaction in lymphoid organs through IL-21 production in myasthenia gravis
Shinji Ashida, MD – Department of Neurology, Kyoto Prefectural University of Medicine; Chihiro Fujii, MD, PhD – Department of Neurology, Kyoto Prefectural University of Medicine; Yoichiro Okada, MD, PhD – Department of Neurology, Kansai Medical University Medical Center; Kimitoshi Kimura, MD, PhD – Department of Neurology, Kyoto University Graduate School of Medicine; Yuichiro Hashi, MD – Department of Neurology, Kansai Medical University Medical Center; Mio Hamatani, MD – Department of Neurology, Kyoto University Graduate School of Medicine; Ryusei Nishigori, MD – Department of Neurology, Kyoto University Graduate School of Medicine; Hirofumi Ochi, MD, PhD – Department of Geriatric medicine, Ehime University Graduate School of Medicine; Kazuyuki Kawamura, MD, PhD – Department of Neurology, National Hospital Organization Minami Kyoto Hospital; Kiyoshi Nokihara, PhD – HiPep Laboratories; Ryosuke Takahashi, MD, PhD – Department of Neurology, Kyoto University Graduate School of Medicine; Toshiki Mizuno, MD, PhD – Department of Neurology, Kyoto Prefectural University of Medicine; Takayuki Kondo, MD, PhD – Department of Neurology, Kansai Medical University Medical Center
Thursday, Jun 20
6:15 pm

H. 19 - High-Dimensional Profiling of Single Memory CD8+T cells Reveals a Specific Pattern in Multiple Sclerosis Patients
Emilie Dugast, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Isabel Vogel, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, Franc; Amedee Renand, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Alexandra Garcia – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Bryan Nicol, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Jeremy Morille – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Marylene Jacq-Foucher – CIC Neurologie-CHU Nantes; Fabienne Le Frère – CIC Neurologie-CHU Nantes; Sandrine Wiertlewski, MD – Service de Neurologie, CHU Nantes, Nantes, France; Arnaud Nicot, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Laure Michel, MD, PhD – Service de Neurologie, CHU Nantes, Nantes, France; Laureline Berthelot, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Pierre-Antoine Gourraud, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Serge Nataf, MD, PhD – University Lyon-1, Lyon University Hospital ("Hospices Civils de Lyon"), CarMeN Laboratory (INSERM 1060) Lyon, France; Karine Tarte, PhD – MICA, INSERM U917, Rennes, France; David-Axel Laplaud, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France
Thursday, Jun 20
6:15 pm

H. 20 - Influence of a SESN3 risk allele on CD4+ T cells and Multiple Sclerosis susceptibility
Chunsheng Ruan, PhD – Columbia University; Tina Roostaei, PhD – Columbia University; Alexandra Kroshilina, BS – Columbia University; Hans-Ulrich Klein, PhD – Columbia University; Philip De Jager, MD, PhD – Columbia University Medical Center; Wassim Elyaman, PhD – Columbia University Medical Center
Thursday, Jun 20
6:15 pm

H. 21 - Multiple sclerosis-associated IL2RA gene variants, rs2104286 and rs11256593, affect expression of CD25 on CD4+ , but not CD8+, T cell subsets in genotype-selected healthy controls
Sophie Buhelt – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet; Helle Bach Søndergaard – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet; Annette Oturai – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet; Henrik Ullum – Department of Clinical Immunology, Center of Clinical Investigation, Copenhagen University Hospital, Rigshospitalet; Marina Rode von Essen – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet; Finn Sellebjerg – Danish Multiple Sclerosis Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet
Thursday, Jun 20
6:15 pm

H. 22 - Pentraxin 3 is useful to differentiate infections from flares in SLE patients with Systemic Inflammatory Response.
Lady J Ríos-Serna – Universidad Icesi, Fundación Valle del Lili; Maria-Claudia Barrera – Universidad Icesi, Fundación Valle del Lili; Cristian C Aragón – Universidad Icesi, Fundación Valle del Lili; Ivana Nieto-Aristizábal – Fundación Valle del Lili; Valentina Lara-Erazo – Universidad Icesi; Philippe Leib – Universidad Icesi; Alejandro Moreno – Universidad Icesi; Juan-Camilo Naranjo – Universidad Icesi, Fundación Valle del LIli; Ivan Posso-Osorio – Universidad Icesi, Fundación Valle del Lili; David Aguirre-Valencia – Universidad Icesi,Fundación Valle del Lili; Alex Echeverri – Universidad Icesi, Fundación Valle del Lili; Carlos A Cañas – Universidad Icesi, Fundación Valle del Lili; Gabriel J. Tobón – Fundacion Valle del Lili, Universidad Icesi, School of Medicine
Thursday, Jun 20
6:15 pm

H. 23 - Single-cell RNA-sequencing of human microglia reveals subtype-specific association with neurological disorders
Vilas Menon, PhD – Columbia University Medical Center; Marta Olah, PhD – Columbia University Medical Center; Mariko Taga, PhD – Columbia University Medical Center; Naomi Habib, PhD – Hebrew University of Jerusalem; Wassim Elyaman, PhD – Columbia University Medical Center; Elizabeth Bradshaw, PhD – Columbia University Medical Center; David Bennett, MD – Rush University Medical Center; Philip De Jager, MD, PhD – Columbia University Medical Center
Thursday, Jun 20
6:15 pm

H. 24 - Interleukin-34 Provides Neuroprotection in a Mouse Model of Experimental Autoimmune Uveitis
Mary J. Mattapallil, MVSc; PhD – National Eye Institute; Yingyos Jittayasothorn, PhD – Lab Immunol, NEI, NIH; Zhijian Wu, MD; PhD – NEI/NIH; Wenxin Ma, PhD – NEI/NIH; Wai Wong, MD; PhD – NEI/NIH; Rachel Caspi, PhD – Lab. Immunology/National Eye Institute/National Institutes of Health
Thursday, Jun 20
6:15 pm

H. 25 - Compartmentalization, persistence and conserved motifs of dominant (regulatory) T cell clones in autoimmune inflammation
Gerdien Mijnheer – University Medical Centre Utrecht; Jing Yao Leong, PhD – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Arjan Boltjes – University Medical Centre Utrecht; Alessandra Petrelli – San Raffaele Diabetes Research Institute; Bas Vastert – University Medical Centre Utrecht; Eric Spierings – University Medical Centre Utrecht; Rob de Boer – Utrecht University; Salvatore Albani – Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre; Aridaman Pandit – University Medical Centre Utrecht; Femke van Wijk, PhD – University Medical Centre Utrecht
Thursday, Jun 20
6:15 pm

H. 26 - PPP2R2B Facilitates the Persistence of Chronic Inflammation through an Epigenetic Mechanism
Iris K. Madera-Salcedo, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Beatriz Sánchez-Hernández, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Yevgeniya Svyryd, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Marcela Esquivel-Velázquez, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Noé Rodríguez-Rodríguez, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; María Isabel Trejo-Zambrano – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; H. Benjamín García-González – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Gabriela Hernández-Molina, MD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Osvaldo Mutchinick, MD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Jorge Alcocer-Varela, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Florencia Rosetti, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Jose C. Crispin, MD, PhD – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Thursday, Jun 20
6:15 pm

H. 27 - R848 (Resiquimod), a TLR 7/8 Agonist, accelerates disease and causes a fatal myeloproliferative disorder in NZM 2410 lupus mice
Jena Wirth, MS – MUSC; Ivan Molano, BS – MUSC; Gary S. Gilkeson, M.D. – Medical University of South Carolina; Phillip Ruiz, MD – University of Miami; Sheryl Coutermarsh-Ott, DVM, PhD – Virginia Tech; Melissa A. Cunningham, M.D., Ph.D. – Medical University of South Carolina
Thursday, Jun 20
6:15 pm

H. 28 - Salivary IgA as biomarker of disease activity in Systemic Lupus Erythematosus.
Sandra Romero Ramírez, MSc – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Erick Saúl Sánchez-Salguero, MSc – CINVESTAV-IPN; José Jiram Torres-Ruíz, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Carlos Núñez-Álvarez, MD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; Rommel Chacón-Salinas, PhD – Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional; Leopoldo Santos-Argumedo, PhD – CINVESTAV-IPN; Diana Gómez-Martín, MD, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán; José Luis Maravillas-Montero, PhD – Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Thursday, Jun 20
6:15 pm

H. 29 - Serine Arginine-rich Splicing Factor 1 (SRSF1) controls T Lymphocyte Homeostasis through the Control of Anti-apoptotic Bcl-xL in Patients with SLE
Takayuki Katsuyama, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School; Kotaro Iida – Beth Israel Deaconess Medical Center, Harvard Medical School; Vaishali R. Moulton, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 30 - Sulforaphane Inhibits Inflammatory Responses of Primary Human T-cells by increasing ROS and depleting Glutathione
Jie Liang – University Hospital Heidelberg; Beate Jahraus – University Hospital Heidelberg; Emre Balta – University Hospital Heidelberg; Jacqueline Ziegler – University Hospital Heidelberg; Katrin Hübner – University Hospital Heidelberg; Norbert Blank – University Hospital Heidelberg; Beate Niesler – University Hospital Heidelberg; Guido Wabnitz – University Hospital Heidelberg; Yvonne Samstag – University Hospital Heidelberg
Thursday, Jun 20
6:15 pm

H. 31 - Suppression of MyD88 in B cells after Disease Onset Improves Outcomes in Murine Lupus
Jeremy Tilstra, MD, PhD – University of Pittsburgh; Minjung Kim, MS – University of Pittsburgh; Claire Leibler, MD, PhD – University of Pittsburgh; Rachael Gordon, PhD – University of Pittsburgh; Mark Shlomchik, MD, PhD – University of Pittsburgh
Thursday, Jun 20
6:15 pm

H. 32 - Detection of Extracellular Vesicles from Patients with Systemic Lupus Erythematous Serves as a Novel Therapeutic
Ifeoma Okafor, MPH – The Ohio State University Wexner Medical Center Division of Immunology; Nicholas Young, PhD – The Ohio State University Wexner Medical Center Division of Immunology; Giancarlo Valiente – The Ohio State University Wexner Medical Center Division of Immunology; Caitlin Henry – The Ohio State University Wexner Medical Center Division of Immunology; Peter Harb – The Ohio State University Wexner Medical Center Division of Immunology; Emily Schwarz – The Ohio State University Wexner Medical Center Division of Immunology; Kyle Jablonksi, MS – The Ohio State University Wexner Medical Center Division of Immunology; Elisha Roberson, PhD – Washington University School of Medicine Division of Rheumatology; Wael Jarjour, MD – The Ohio State University Wexner Medical Center Division of Immunology
Thursday, Jun 20
6:15 pm

H. 33 - Serine Arginine-rich Splicing Factor 1 (SRSF1) restrains effector T cell responses via the PTEN/mTORC1 pathway in systemic lupus erythematosus
Takayuki Katsuyama, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School; Hao Li, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School; Denis Comte, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School; George Tsokos, MD. – Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; Vaishali R. Moulton, MD, PhD – Beth Israel Deaconess Medical Center, Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 34 - All leukocytes contribute specific transcripts to the SLE blood signature
Djamel Nehar-Belaid – THE JACKSON LABORATORY; Seunghee Hong – Drukier Institute for Children’s Health, Weill Cornell Medicine; Radu Marches – THE JACKSON LABORATORY; Jeanine Baisch – Drukier Institute for Children’s Health, Weill Cornell Medicine; Lynnette Walters – Texas Scottish Rite Hospital for Children; Tracey Wright – UT Southwestern Medical Center,; Robert Rossi – THE JACKSON LABORATORY; Octavio Ramilo – Nationwide Children's Hospital and the Ohio State University School of Medicine, Division of Pediatric Infectious Diseases; Paul Robson – THE JACKSON LABORATORY; Virginia Pascual – Drukier Institute for Children’s Health, Weill Cornell Medicine; Jacques Banchereau – THE JACKSON LABORATORY
Thursday, Jun 20
6:15 pm

H. 35 - Estrogen induction of Interstital Lung Disease is mediated through PD-1+Th17 cell-dependent and -independent signaling pathways
Wonder Drake – Vanderbilt University School of Medicine; Ozioma Chioma – Vanderbilt University Medical Center; Natalie Hassell – Vanderbilt University; Kenny Abel – Vanderbilt University Medical Center; Lindsay Celada – Vanderbilt University Medical Center; Dawn Newcomb – Vanderbilt University School of Medicine
Thursday, Jun 20
6:15 pm

H. 36 - Graft GD T-Cell Receptor Sequencing Identifies Public Clonotypes Associated to HSCT Efficacy in AML Patients and Unravels CMV Impact on Repertoire Distribution
Lucas CM. Arruda – Karolinska Institutet, CLINTEC; Ahmed Gaballa – Karolinska Institutet, CLINTEC; Michael Uhlin, PhD – Karolinska Institute, CLINTEC
Thursday, Jun 20
6:15 pm

H. 37 - A CD45-Targeted Antibody Drug Conjugate Enables Allogeneic Hematopoietic Stem Cell Transplantation in Mice
Sharon L. Hyzy – Magenta Therapeutics; Rahul Palchaudhuri, Ph.D. – Magenta Therapeutics; Jennifer L. Proctor – Magenta Therapeutics; Brad R. Pearse, Ph.D. – Magenta Therapeutics; Ganapathy N. Sarma, Ph.D. – Magenta Therapeutics; Geoffrey O. Gillard, Ph.D. – Magenta Therapeutics; Hillary L. Adams – Magenta Therapeutics; Tahirih L. Lamothe – Magenta Therapeutics; Melissa Brooks – Magenta Therapeutics; Andrew Gabros – Magenta Therapeutics; Charlotte F. McDonagh, Ph.D. – Magenta Therapeutics; Anthony E. Boitano, Ph.D. – Magenta Therapeutics; Michael P. Cooke, Ph.D. – Magenta Therapeutics
Thursday, Jun 20
6:15 pm

H. 38 - A longitudinal analysis of TCRB repertoire diversity in immune tolerance of pediatric patients post-UCBT: T cell clonal deletion over clonal anergy
Xiaohua Chen, MD PhD – UPMC/Children's Hospital of Pittsburgh/Blood and Marrow Transplantation and Cellular Therapy; Paul Szabolcs, MD – UPMC/Children's Hospital of Pittsburgh/Blood and Marrow Transplantation and Cellular Therapy
Thursday, Jun 20
6:15 pm

H. 39 - Anti-CD45RC MAb treatment prevents acute graft-vs.-host disease (aGVHD) induces alloimmune tolerance and preserves protective immune responses.
Laetitia Boucault – INSERM UMR 1064-CRTI, Nantes, France; Maria Lopez-Robles – INSERM UMR 1064-CRTI, Nantes, France; Séverine Bézie – INSERM UMR 1064-CRTI, Nantes, France; Eliane Piaggio – INSERM U932-Institut Curie; Carole Guillonneau – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO; Ignacio Anegon – INSERM UMR 1064-CRTI, Nantes, France
Thursday, Jun 20
6:15 pm

H. 40 - B-cells reconstitution in systemic sclerosis patients after autologous hematopoietic stem cell transplantation
Joao Rodrigues. Lima Junior – Program of Graduation on Biosciences and Biotechnology, School of Pharmaceutical Sciences/Center for Cell-based Therapy, Regional Blood Center of Ribeirão Preto/University of Sao Paulo; Lucas CM Arruda – Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Maynara S Gonçalves – Program of Graduation on Basic and Applied Immunology, Ribeirão Preto Medical School, University of São Paulo; Julia TC de Azevedo – Ribeirão Preto Medical School, University of São Paulo; Daniela A Moraes – Division of Clinical Immunology Ribeirao Preto Medical School; Dimas T Covas – Center for Cell-based Therapy, Regional Blood Center of Ribeirao Preto, Ribeirao Preto Medical School, University of Sao Paulo; Maria C Oliveira – Division of Clinical Immunology Ribeirao Preto Medical School; Kelen CR Malmegrim – Program of Graduation on Biosciences and Biotechnology, Department of Clinical, Toxicological and Bromatological Analysis, School of Pharmaceutical Sciences of Ribeirão Preto
Thursday, Jun 20
6:15 pm

H. 41 - In vitro Glucocorticoid Responsiveness of HSCT Graft cells in Acute Graft-versus-Host Disease in Allogeneic Hematopoietic Stem Cell Transplantation
Truls Gråberg, M.D. – Department of Clinical science, Intervention and Technology (CLINTEC), Division of Surgery; Lovisa Strömmer, MD, PhD – Karolinska Institute, Huddinge Hospital; Michael Uhlin, PhD – Karolinska Institute, CLINTEC; Arwen Stikvoort, PhD – Karolinska Institute, Huddinge Hospital; Ann-Charlotte Wikström, MD, PhD – Karolinska University Hospital
Thursday, Jun 20
6:15 pm

H. 42 - MSCs Interacting with Neutrophils Results in Specific Immunomodulatory Cytokine Signatures – Does it Vary with Sources?
Ahmed M. Al-Hakami, MBBS, MSc, PhD – King Khalid University; Saad Qaddah Mossa. Al-Hakami, MD, FRCP – King Khalid University; Sharaz Shaik, PhD – King Khalid University; Anantharam Devaraj, PhD – King Khalid University; Harish C Chandramoorthy, PhD – King Khalid University
Thursday, Jun 20
6:15 pm

H. 43 - Non-Genotoxic Conditioning with Antibody-Drug Conjugates Targeting CD45 Effectively Deplete Hematopoietic Stem Cells and Lymphocytes
Geoffrey O. Gillard, Ph.D. – Magenta Therapeutics; Rahul Palchaudhuri, Ph.D. – Magenta Therapeutics; Brad R. Pearse, Ph.D. – Magenta Therapeutics; Jennifer L. Proctor – Magenta Therapeutics; Sharon L. Hyzy – Magenta Therapeutics; Anjali Bhat – Magenta Therapeutics; Sean McDonough – Magenta Therapeutics; Ganapathy N. Sarma, Ph.D. – Magenta Therapeutics; Danielle Ladwig – Magenta Therapeutics; Qing Li, Ph.D. – Magenta Therapeutics; Nidhi Jain – Magenta Therapeutics; Rajiv Panwar, Ph.D. – Magenta Therapeutics; Pranoti Sawant – Magenta Therapeutics; Junia Dushime – Magenta Therapeutics; Patrick Falahee, Ph.D. – Magenta Therapeutics; Lena Kien – Magenta Therapeutics; Tahirih L. Lamothe – Magenta Therapeutics; Andrew Gabros – Magenta Therapeutics; Anthony E. Boitano, Ph.D. – Magenta Therapeutics; Charlotte F. McDonagh, Ph.D. – Magenta Therapeutics; Anthony E. Boitano, Ph.D. – Magenta Therapeutics; Michael P. Cooke, Ph.D. – Magenta Therapeutics
Thursday, Jun 20
6:15 pm

H. 44 - Finding transcriptional regulators central to RA with transcriptomics of IL-17 dose response, time series, and gene silencing in stromal cells
Kamil Slowikowski – Harvard University; Hung N. Nguyen, PhD – Brigham and Women's Hospital; Gerald FM. Watts, M.Sc. – Brigham and Women's Hospital; Fumitaka Mizoguchi, MD, PhD – Tokyo Medical and Dental University; Erika H. Noss, MD, PhD – University of Washington; Michael B. Brenner, MD – Brigham and Women's Hospital/Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 45 - Association of systemic inflammation in COPD patients with and without pulmonary hypertension of Bangladesh
Amena Majid – BIRDEM General Hospital; Abu Taher Sarker – BIRDEM General Hospital; Mansura Khan – BIRDEM General Hospital; Ashesh Kumar. Chowdhury, Head, Dept. of Immunology – BIRDEM General Hospital
Thursday, Jun 20
6:15 pm

H. 46 - CD4+ T-cell Phenotypes and Activation of the JAK/STAT Pathway in PBMCs from Newly Diagnosed Parkinson’s Disease Patients
Hongwei Qin – University of Alabama at Birmingham; Zhaoqi Yan – University of Alabama at Birmingham; Wei Yang – University of Alabama at Birmingham; Marissa Dean – University of Alabama at Birmingham; David Standaert – University of Alabama at Birmingham; Gary Cutter – University of Alabama at Birmingham; Etty Benveniste – University of Alabama at Birmingham
Thursday, Jun 20
6:15 pm

H. 47 - Development of Chemotaxis Assays for Human-blood Derived Neutrophils and Monocytes Suitable for the Identification and Validation of Potential Drug Targets
Lisa Scandiuzzi – Charles River Laboratories; Monique Hazenoot – Charles River Laboratories; Yasmin Habani – Charles River Laboratories; Sanne Laura. Demandt – Charles River Laboratories; Jeroen DeGroot, PhD – Charles River Laboratories; Jamil Aarbiou, PhD – Charles River Laboratories
Thursday, Jun 20
6:15 pm

H. 48 - Evaluation of Novel Adipokines (Omentin-1, Apelin and Chemerin) as Potential Biomarkers of Presence and Severity of Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients
Md Yasir, M.D. – NEIGRIHMS; Gp Senthilkumar, Ph.D. – JIPMER
Thursday, Jun 20
6:15 pm

H. 49 - Highly Aggregated mAb Therapeutics Can Induce Production of Proinflammatory Cytokine Responses
Rozaleen Dash – Indian Institute of Technology- Delhi; Anurag S. Rathore – Indian Institute of Technology- Delhi
Thursday, Jun 20
6:15 pm

H. 50 - Innate Regulation of Tissue-Reparative Human Regulatory T Cells
Avery J. Lam – The University of British Columbia; Katherine N. MacDonald – University of British Columbia; Anne M. Pesenacker, Ph.D. – University College London; Stephen C. Juvet, M.D., Ph.D. – University of Toronto; Kimberly A. Morishita, M.D. – University of British Columbia; Brian Bressler, M.D. – Department of Medicine, University of British Columbia; iGenoMed Consortium – iGenoMed Consortium; James G. Pan, Ph.D. – University of Toronto; Sachdev S. Sidhu, Ph.D. – University of Toronto; John D. Rioux, Ph.D. – Université de Montréal; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia
Thursday, Jun 20
6:15 pm

H. 51 - Interleukin-34 Contributes to Treg Suppressive Function
Antoine Freuchet – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Université de Nantes, Nantes, France; Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Séverine Bézie – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Claire Usal, research assistant – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Université de Nantes, Nantes, France; Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Véronique Nerrière-Daguin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Carole Guillonneau – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO; Ignacio Anegon – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.
Thursday, Jun 20
6:15 pm

H. 52 - Regulation of IL-10-producing T cells by polyunsaturated fatty acids
Jaileene Hernandez Escalante – Boston University School of Medicine; Albert Jones, IV, MA – Boston University School of Medicine; Victoria Volfson Sedletsky – Boston University School of Medicine; Hans Dooms, PhD – Boston University School of Medicine
Thursday, Jun 20
6:15 pm

H. 53 - Serum Interleukin-27 (IL-27) Levels in Patients with Psoriatic Arthritis
Goksal Keskin, Immunology – Bay; Ali Inal, Immunology – Bay; Pamir Çerci, Immunology – Bay; Esra Dilek. Keskin – female
Thursday, Jun 20
6:15 pm

H. 54 - Suppression of inflammatory cytokine production and cell proliferation by salt-inducible kinase inhibition in human myeloid cells is isoform-dependent
Zhifei Shao, M.D., Ph.D. – Amgen Inc; Joy Wang – Amgen Inc; Taryn Cariaga – Amgen Inc; Antony Symons, Ph.D. – Amgen Inc
Thursday, Jun 20
6:15 pm

H. 55 - The transcription factor IKZF3 is associated with, but not sufficient for, IL-10 expression in human CD4+ T cells
Michael L. Ridley – Kings College London; Veerle Fleskens – King's College London; Ceri A. Roberts – NHS; Sylvine Lalnunhlimi – King's College London; Giovanni AM. Povoleri – King's College London; Paul Lavender – King's College London; Leonie S. Taams – King's College London
Thursday, Jun 20
6:15 pm

H. 56 - Granzyme B secreting B cell as a potential cell therapeupic target
Mélanie Chesneau – CRTI UMR1064, INSERM, Université de Nantes; Richard Danger – CRTI UMR1064, INSERM, Université de Nantes; Sabine Le Bot – Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Béatrice Charreau – CRTI UMR1064, INSERM, Université de Nantes; Michel Cogne, VDM, PHD – CNRS UMR 7276 / INSERM U1262, CRIBL, Université de Limoges; Nicolas Degauque, PhD – CRTI UMR1064, INSERM, Université de Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes
Thursday, Jun 20
6:15 pm

H. 57 - Role of the intracellular ion channels TMEM176A and TMEM176B in the immune system
Mélanie Lancien – CRTI UMR1064; Géraldine Bienvenu Louvet – CRTI UMR 1064; Lucile Guéno – CRTI UMR 1064; Aurelie Moreau – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Sonia Salle – CRTI UMR 1064; Emmanuel Merieau – CRTI UMR 1064; Laurence Bouchet-Delbos – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Flora Coulon – CRTI UMR 1064; Gaëlle Boncompain – Institut Curie; Franck Perez – Institut Curie; Maria-Cristina Cuturi – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Cédric Louvet – CRTI UMR 1064
Thursday, Jun 20
6:15 pm

H. 58 - Altered composition and proinflammatory function of neutrophil extracellular traps in type 1 diabetes
Anna Sediva, MD,PhD – Motol University Hospital and 2nd Medical Faculty Prague, Czech Republic; Zuzana Parackova, Student – Motol University Hospital and 2nd Faculty of Medicine Prague, Czech Republic; Irena Zentsova – Motol University Hospital and 2nd Faculty of Medicine Prague, Czech Republic; Adam Klocperk – Motol University Hospital and 2nd Faculty of Medicine Prague, Czech Republic; Zdenek Sumnik – Motol University Hospital and 2nd Faculty of Medicine Prague, Czech Republic; Stepanka Pruhova – Motol University Hospital and 2nd Faculty of Medicine Prague, Czech Republic; Lenka Petrutzelkova – Motol University Hospital and 2nd Faculty of Medicine Prague, Czech Republic
Thursday, Jun 20
6:15 pm

H. 59 - TSHR isoforms differential expression in thyroid and thymus: implications for the autoimmune response in Graves' Disease
Ana Marín-Sánchez; Alicia Sellés-Sánchez – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Francesc Rudilla – Histocompatibility and Immunogenetics Laboratory, Blood and Tissue Bank; Transfusional Medicine Group, Vall d’Hebron Research Institute (VHIR); Daniel Alvarez-Sierra – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Roger Colobran – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB); Ricardo Pujol-Borrell – Hospital Universitari Vall d’Hebron (HUVH) and Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB)
Thursday, Jun 20
6:15 pm

H. 60 - Type 1 Diabetes Alters Key Immune Circadian Patterns
Craig A. Beam, PhD – Western Michigan University; Clive Wasserfall, PhD – University of Florida; Eleni Beli, MD – Indiana University Purdue University; Kieran McGrail – University of Florida; Alyssa Woodwyk, MS – Western Michigan University Homer Stryker M.D. School of Medicine; Mark Atkinson, PhD – University of Florida; Linda DiMeglio, MD – Indiana University Purdue University
Thursday, Jun 20
6:15 pm

H. 61 - Personalized Immune Mice Model Genetically-Predetermined Immune Dysregulation of Patients with T1D
Mohsen Khosravi-Maharlooe, MD/MSc – Columbia University; Nichole Danzl, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Chiara Borsotti, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Sean Campbell R., MD/PhD – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Aleksandar Obradovic – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Todd M. Brusko, Ph.D. – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Kortney Rogers, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Robin Goland, MD – Columbia University; Sarah Pollak – Columbia University; Robert Winchester, MD – Columbia University; David G. Savage, MD – Columbia University; Megan Sykes, M.D. – Columbia Center for Translational Immunology, Department of Medicine; Department of Microbiology & Immunology; Department of Surgery, Columbia University Medical Center
Thursday, Jun 20
6:15 pm

H. 62 - Expansion of Insulin-Specific Regulatory T Cells Restricted to HLA-DQ6
Angela M. Mitchell, PhD – University of Colorado Anschutz Medical Campus; Aimon K. Alkanani – University of Colorado Anschutz Medical Campus; Kristen A. McDaniel – University of Colorado Anschutz Medical Campus; Laurie G. Landry, PhD – University of Colorado Anschutz Medical Campus; Maki Nakayama, MD – University of Colorado Anschutz Medical Campus; Aaron W. Michels, MD – University of Colorado Anschutz Medical Campus
Thursday, Jun 20
6:15 pm

H. 63 - SUSD4 Affects Interleukin-1β Regulation of Glucose Stimulated Insulin Secretion
Bilgi Gungor – Lund University, Department of Translational Medicine; Wouter Van Overbeke – Lund University, Department of Translational Medicine; Ben C. King – Lund University, Department of Translational Medicine; Mikael Sigvardsson – Lund University, Department of Laboratory Medicine; Ulrika Krus – Lund University, Department of Clinical Sciences; Anja Schmidt-Christensen – Lund University, Department of Experimental medical Science; Dan Holmberg – Lund University, Department of Experimental medical Science; Jonathan Esguerra – Lund University, Department of Clinical Sciences; Erik Renström – Lund University, Department of Clinical Sciences; Anna Blom – Lund University, Department of Translational Medicine
Thursday, Jun 20
6:15 pm

H. 65 - BTLA Stimulation Protects Against Atherosclerosis by Regulating Follicular B cells
Amanda Foks – Leiden University, Leiden Academic Centre for Drug Research; Hidde Douna – Leiden University, Leiden Academic Centre for Drug Research; Jacob Amersfoort – Leiden University, Leiden Academic Centre for Drug Research; Frank Schaftenaar – Leiden University, Leiden Academic Centre for Drug Research; Marie Depuydt – Leiden University, Leiden Academic Centre for Drug Research; Hideo Yagita – Department of Immunology, Juntendo University School of Medicine; Christoph Binder – Department of Laboratory Medicine, Medical University of Vienna; Ilze Bot – Leiden University, Leiden Academic Centre for Drug Research; Johan Kuiper – Leiden University, Leiden Academic Centre for Drug Research
Thursday, Jun 20
6:15 pm

H. 66 - Single-cell analysis of autoreactive CD4 T cells reveals an atypical B helper signature in autoimmune hepatitis
Amedee Renand, PhD – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Iñaki Cervera-Marzal – Aix Marseille University, CNRS, INSERM, CIML, Marseille, France; Hélène Auble, Pharm.D – Centre d'Investigation Clinique gastro-nutrition, CHU Nantes, Nantes, France; Laurine Gil – Aix Marseille University, CNRS, INSERM, CIML, Marseille, France; Erwan Kervagoret – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; Sarah Habes, M.D – Service Hepato-gastro-entérologie et Assistance Nutritionnelle, CHU Nantes, Nantes, France; Jean-François Mosnier, M.D – Service Anatomie et Cytologie Pathologiques, CHU Nantes, Nantes, France; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Jérôme Gournay, M.D – Service Hepato-gastro-entérologie et Assistance Nutritionnelle, CHU Nantes, Nantes, France; Pierre Milpied, PhD – Aix Marseille University, CNRS, INSERM, CIML, Marseille, France; Sophie Conchon – CRTI UMR1064, INSERM, Université de Nantes, Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France
Thursday, Jun 20
6:15 pm

H. 68 - Role of C4A and C4B in SLE susceptibility and development
Lea Simoni – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Jessy Presumey – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Cees E. van der Poel – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine; Michael Carroll – Boston Children's Hospital / Harvard Medical School, Program in Cellular and Molecular Medicine
Thursday, Jun 20
6:15 pm

H. 69 - Study of Allele-Specific Expression Reveals Subset- and State- dependent Regulation of Select Genes involved in TNF Signaling by Autoimmunity-Associated Variants
Hani S. Mousa, M.D – University of Cambridge; Daniel R. Rainbow – University of Oxford; Alasdair J. Coles, FRCP, Ph.D – University of Cambridge; Linda S. Wicker, Ph.D – University of Oxford; Joanne L. Jones, MRCP, Ph.D – University of Cambridge
Thursday, Jun 20
6:15 pm

H. 70 - Study of genetic variants of the MTHFR and FGG systems and their association with adipokynes in Pediatric Lupus Nephritis-pLN-. In search of risk factors associated with atheromatosis
Eduardo Egea – Universidad del Norte, Barranquilla, Colombia.; Gloria Garavito – Universidad del Norte, Barranquilla, Colombia. Universidad Simon Bolivar, Barranquilla, Colombia.; Nicole Pereira – Universidad del Norte, Barranquilla, Colombia. Universidad Simón Bolívar, Barranquilla, Colombia; Luis Fang – Universidad del Norte, Barranquilla, Colombia.; Gustavo Aroca – Universidad del Norte, Barranquilla, Colombia. Universidad Simon Bolivar, Barranquilla, Colombia.; Zilac Espítatela – Universidad Simón Bolívar, Barranquilla, Colombia.; Clara Malagón – Universidad el Bosque, Bogota, Colombia.; Antonio Iglesias – Universidad del Norte, Barranquilla, Colombia.; Ana Moreno-Woo – Universidad del Norte, Barranquilla, Colombia.
Thursday, Jun 20
6:15 pm

H. 71 - The IL6RAsp358Ala autoimmunity risk genotype is associated with alterations in the transcriptional signature of T cells in response to IL-6
Kirsten E. Diggins, PhD – Benaroya Research Institute; Britta E. Jones, PhD – Benaroya Research Institute; Megan D. Maerz – Benaroya Research Institute; Peter Linsley, Ph.D. – Benaroya Research Institute at Virginia Mason; Jane H. Buckner, M.D. – Benaroya Research Institute at Virginia Mason
Thursday, Jun 20
6:15 pm

H. 72 - The Vm24 Scorpion Toxin Blocks Kv1.3 Potassium Channels and Attenuates the Effector Memory T Cell Response
José I. Veytia-Bucheli, PhD student – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Juana M. Jiménez-Vargas, PhD – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Erika I. Melchy-Pérez, Biologist – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Monserrat A. Sandoval-Hernández, PhD student – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Rita Restano-Cassulini, PhD – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Raquel Sánchez-Gutiérrez, PhD student – Centro de Investigación en Ciencias de la Salud y Biomedicina. Universidad Autónoma de San Luis Potosí.; Lesly Doniz-Padilla, PhD – Centro de Investigación en Ciencias de la Salud y Biomedicina. Universidad Autónoma de San Luis Potosí.; Berenice Hernández-Castro, PhD – Centro de Investigación en Ciencias de la Salud y Biomedicina. Universidad Autónoma de San Luis Potosí.; Carlos Abud-Mendoza, Rheumatologist – Hospital Central “Dr. Ignacio Morones Prieto”.; Roberto González-Amaro, PhD – Centro de Investigación en Ciencias de la Salud y Biomedicina. Universidad Autónoma de San Luis Potosí.; Lourival D. Possani, PhD – Instituto de Biotecnología. Universidad Nacional Autónoma de México.; Yvonne Rosenstein, PhD – Instituto de Biotecnología. Universidad Nacional Autónoma de México.
Thursday, Jun 20
6:15 pm

H. 73 - System Simulation as an Aid to Immunological Research
Kenneth Cooper – System Dynamics Society
Thursday, Jun 20
6:15 pm

H. 74 - What really is the role of the immune system
Eduardo Finger
Thursday, Jun 20
6:15 pm

H. 75 - Patients with PIK3CD gain-of-function mutations show PI3K controls B cell self-tolerance outside the germinal center
Anthony Lau – Garvan Institute; Danielle Avery – Garvan Institute of Medical Research; Julia Bier – Garvan Institute; Stuart Tangye, PhD – Garvan Institute of Medical Research; Elissa Deenick, PhD – Garvan Institute
Thursday, Jun 20
6:15 pm

H. 76 - Annotation of single cell populations using high-dimensional epigenomic profiles
Tiffany J. Amariuta, BS – Harvard Medical School; Yang Luo, PhD – Harvard Medical School; Fan Zhang, PhD – Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 77 - Assessing Power for Single Cell RNA-sequencing Association Studies
Chamith Y. Fonseka, B.S. – Harvard Medical School; Ilya Korsunsky, PhD – Harvard Medical School; Nghia Millard, B.S. – Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 78 - Dynamic Allelic Expression during T Cell Activation Uncovers cis Regulatory Effects in HLA-DQB1 and Autoimmune Disease Genes
Maria Gutierrez-Arcelus, PhD – Brigham and Women's Hospital, Harvard Medical School; Yuriy Baglaenko, PhD – Brigham and Women's Hospital, Harvard Medical School; Susan Hannes – Brigham and Women's Hospital; Jatin Arora – Max Planck; Nikola Teslovish – Brigham and Women's Hospital; Yang Luo, PhD – Harvard Medical School; Kamil Slowikowski – Brigham and Women's Hospital; Tiffany J. Amariuta, BS – Harvard Medical School; Harm-Jan Westra, PhD – Brigham and Women's Hospital; Deepak Rao, MD – Brigham and Women's Hospital; Joerg Ermann, MD – Brigham and Women's Hospital; Anna Helena Jonsson, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Tonu Esko, PhD – University of Tartu; Michael B. Brenner, MD – Brigham and Women's Hospital/Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 79 - Genetic drivers of stimulation response in immune cells exhibit disease specificity
Nikolaos Patsopoulos, MD, PhD – Brigham & Women's Hospital, Harvard Medical School, Broad Institute; Ioannis Vlachos, PhD – Beth Israel Medical Center; Zhou Fang, PhD – Brigham & Women's Hospital, Harvard Medical School; Daniel Hui, BSc – Brigham & Women's Hospital, Harvard Medical School; Hans-Urlich Klein, PhD – Columbia University Medical Center; Philip De Jager, MD, PhD – Columbia University Medical Center; Vijay Kuchroo, PhD – Brigham & Women's Hospital, Harvard Medical School, Broad Institute; Howard Weiner, MD – Brigham and Women's Hospital, Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 80 - Harmony enables the simultaneous single cell RNAseq analysis of circulating and infiltrating immune cells across donors and tissues
Ilya Korsunsky, PhD – Harvard Medical School; Jean Fan, PhD – Harvard University; Kamil Slowikowski – Brigham and Women's Hospital; Fan Zhang, PhD – Harvard Medical School; Kevin Wei, MD, PhD – Brigham and Women's Hospital/Harvard Medical School; Yuriy Baglaenko, PhD – Harvard Medical School; Michael B. Brenner, MD – Brigham and Women's Hospital/Harvard Medical School; Po-Ru Loh, PhD – Harvard Medical School; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 81 - Higher Native American ancestry proportion is associated with increased TB progression risk in the Peruvian population
samira asgari, PhD – Harvard Medical School - BWH; Yang Luo, PhD – Harvard Medical School; Roger Calderon, Boston – Socios En Salud ; Leonid Lecca, PhD – Socios En Salud ; Judith Jimenez, PhD – Socios En Salud ; Rosa Yataco, PhD – Socios En Salud ; Carmen Contreras, PhD – Socios En Salud ; Jerome T. Galea, PhD – Harvard Medical School - BWH; Megan B Murray, MD/PhD – Harvard Medical School - BWH; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 82 - Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP K-regulated Transcriptional Enhancer Contributing to SLE Susceptibility
Swapan K. Nath, Ph.D. – Oklahoma Medical Research Foundation
Thursday, Jun 20
6:15 pm

H. 83 - Immune Atlas of Second Trimester Human Intestine, Liver and Spleen
Liza Konnikova, MD, PhD – UPMC Childrens Hospital of Pittsburgh; Stephanie Stras, BA – UPMC Childrens Hospital of Pittsburgh; Lael Werner, PhD – Edmond and Lily Safra Children's Hospital; Jessica Toothaker, BA – University of Pittsburgh; Oluwabunmi Konnikova, MD – University of Pittsburgh; Austin Oldham – University of Pittsburgh; Dror Shouval, MD – Edmond and Lily Safra Children's Hospital
Thursday, Jun 20
6:15 pm

H. 84 - Biomarker harmonization to measure immunological effects of ustekinumab in type 1 diabetes
Kirsten Ward Hartstonge, Ph.D. – Department of Surgery, The University of British Columbia, and Child & Family Research Institute, Vancouver, Canada; Jennie Hsui Mien Yang, Ph.D. – Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Ashish Marwaha, BMBCh, MA(Oxon), Ph.D. – Department of Genetics, University of Toronto, Toronto, Canada & Department of Dermatology and Skin Science, The university of British Columbia, Vancouver, Canada; Eleni Christakou – Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Evangelia Williams – Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Anne Pesenacker, Ph.D. – Department of Surgery, The University of British Columbia, and Child & Family Research Institute, Vancouver, Canada & Division of Infection and Immunity, Institute of Immunity & Transplantation, University College London, London, UK; Sabine Ivision, Ph.D. – Department of Surgery, The University of British Columbia, and Child & Family Research Institute, Vancouver, Canada.; Sam Chow – Department of Dermatology and Skin Science, The university of British Columbia, Vancouver, Canada; Thomas Elliott, MBBS – Department of Endocrinology, University of British Columbia, Vancouver, Canada & BC Diabetes, Vancouver, Canada.; Colin Dayan, MA MBBS, FRCP, Ph.D. – Diabetes Research Group, Cardiff University School of Medicine, Cardiff, UK.; Jan Dutz, MD, FRCPC – Department of Dermatology and Skin Science, The university of British Columbia, Vancouver, Canada; Tim Tree, Ph.D. – Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK.; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia
Thursday, Jun 20
6:15 pm

H. 85 - CCA-based Integration of Multimodal Single-Cell Data Identifies Higher-Resolution Immune Cell States
Aparna Nathan – Harvard University; Ilya Korsunsky, PhD – Harvard University; Fan Zhang, PhD – Harvard University; Lixia Li – Merck Research Laboratories; Philip Garrett-Engele – Merck Research Laboratories; Doug Wilson, PhD – Merck Research Laboratories; Shahin Aslam – Merck Research Laboratories; Kelvin Zhang, PhD – Merck Research Laboratories; Vanessa Peterson, PhD – Merck Research Laboratories; Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 86 - CD4+ CD25+ CD127hi cells correlate with disease progression in type 1 diabetes: Validated in a multi-site study
Aditi Narsale, PhD – San Diego Biomedical Research Institute; Rosa Moya – San Diego Biomedical Research Institute; Hannah Robertson – San Diego Biomedical Research Institute; Dawson Payne – San Diego Biomedical Research Institute; Ting Ting Lu – Immune Tolerance Network; Rhonda Geoffrey – Department of Pediatrics, The Medical College of Wisconsin; Kerry Buchana, PhD – Diamantina Institute, University of Queensland; Mark Harris – Diamantina Institute, University of Queensland; Anne-Sophie Bergot – Diamantina Institute, University of Queensland; Ranjeny Thomas, PhD – The University of Queensland Diamantina Institute; Martin J. Hessner, PhD – Department of Pediatrics, The Medical College of Wisconsin; Manuela Battaglia, PhD – Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute; Elisavet Serti, PhD – Immune Tolerance Network; Immune Tolerance Network – Immune Tolerance Network; Joanna D. Davies, PhD – San Diego Biomedical Research Institute
Thursday, Jun 20
6:15 pm

H. 87 - Clustering and Visualization of Influenza-specific CD4+ T Cell Responses
Priyanka B. Subrahmanyam, PhD – Stanford University; Tyson H. Holmes, PhD – Stanford University; Weiqi Wang, PhD – Stanford University; Dongxia Lin, PhD – Stanford University; Laura Su, MD, PhD – Stanford University; Gerlinde Obermoser, MD – Baylor Research Institute; Karolina Palucka, MD, PhD – Baylor Research Institute; Mark M. Davis, PhD – Stanford University; Holden T. Maecker, PhD – Stanford University
Thursday, Jun 20
6:15 pm

H. 88 - Comprehensive Epigenetic Immune Cell Monitoring in Diverse Clinical Applications
Janika Josephin. Schulze, M.Sc. – Epimune GmbH; Jeannette Werner, Dr. rer. nat – Epimune GmbH; Konstantin Schildknecht, Dipl. math. – Epiontis GmbH; Uma Lakshmanan, MS – Stanford University; Andreas Grützkau, Dr. rer. nat – Deutsches Rheuma-Forschungszentrum Berlin; Yael Gernez, MD – Stanford University; Katja Gabriele. Weinacht, MD PhD – Department of Pediatrics, Stem Cell Transplantation, at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA; Alice Bertaina, MD – Stanford University; Udo Baron, Dr. rer. nat. – Epiontis GmbH; Sven Olek, Dr. rer. nat – Epiontis GmbH; Maria Grazia Roncarolo, MD PhD – Stanford University; Rosa Bacchetta, MD – Department of Pediatrics, Human Gene Therapy at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Thursday, Jun 20
6:15 pm

H. 89 - A New Specific Promoter to Control Chimeric Antigen Receptor Expression Allow Long Lasting CAR Therapy using Hematopoietic Stem Cells
Aurélien Colamartino – CHU Sainte-Justine Research Center, Department of Microbiology and Immunology, University of Montreal; Panojot Bifsha – CHU Sainte-Justine Research Center; Chloé Colas – CHU Sainte-Justine Research Center; William Lemieux – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Hugo Romero – CHU Sainte-Justine; Camille Tremblay-Laganière – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Simon Nicoletti – INSERM U1163 and CNRS ERL 8254, Medicine Faculty, Paris Descartes University, Necker Hospital; Mélanie Guiot – UPMC Paris 6, Paris, France / APHP, Paris, France; Andrei Boldici – CHU Sainte Justine Research Center / University of Montreal, Department of Microbiology and Immunology; Yuanyi Li – CHU Sainte Justine Research Center; Elie Haddad – CHU Sainte-Justine Research Center, Department of Microbiology, Infectiology and Immunology, University of Montreal; Department of Pediatrics, University of Montreal
Thursday, Jun 20
6:15 pm

H. 90 - Humoral responses to common dietary antigens leads to accumulation of food antigen-specific plasma cells in the human infant thymus
Hector Cordero, PhD – Columbia University; Jacob Hess – Columbia University; April Myung – Columbia University; Elio Nitschki – Columbia University; Emmanuel Zorn – Columbia University
Thursday, Jun 20
6:15 pm

H. 91 - The role of the mitochondrial protein TCAIM in controlling CD8+ T cell functions
Christina Iwert – Charité - Universitätsmedizin Berlin, Institute for medical Immunology; Julia Kufka – Charité - Universitätsmedizin Berlin, Institute for medical Immunology; Katarina Stanko – Charité - Universitätsmedizin Berlin, Institute for medical Immunology; Julia Schumann – Charité - Universitätsmedizin Berlin, Institute for medical Immunology; Karsten Jürchott – Charité - Universitätsmedizin Berlin, Institute for medical Immunology; Jan Lisec – Charité - Universitätsmedizin Berlin, Institute for medical Immunology; Birgit Sawitzki – Charité - Universitätsmedizin Berlin, Institute for medical Immunology
Thursday, Jun 20
6:15 pm

H. 92 - Tuberculosis and sarcoidosis hold very distinct CD4 T cell transcriptomic profiles that can be used to improve pathology understanding and diagnostic tools
Julie G. Burel – La Jolla Institute for Immunology; Cecilia S. Lindestam Arlehamn – La Jolla Institute for Immunology; Mikhail Pomaznoy – La Jolla Institute for Immunology; Gregory Seumois – La Jolla Institute for Immunology; Jason A. Greenbaum – La Jolla Institute for Immunology; Dhammika Vidanagama – National Tuberculosis Reference Laboratory; Bandu Gunasena – National Hospital for Respiratory Diseases; Rashmi Tippalagama – Genetech Research Institute; Aruna D. deSilva – Genetech Research Institute; Randy Taplitz – University of California San Diego; Wonder Drake – Vanderbilt University School of Medicine; Pandurangan Vijayanand – La Jolla Institute for Immunology; Alessandro Sette – La Jolla Institute for Immunology; Bjoern Peters – La Jolla Institute for Immunology
Thursday, Jun 20
6:15 pm

H. 93 - V delta 1 and V delta 2 gamma delta T cells express different marker signatures and are distinctly linked to plasma markers of systemic inflammation with ART-suppressed HIV infection and normal aging.
Anna Belkina – Boston Universtiy School of Medicine; Riley Pihl – Boston University School of Medicine; Alex Olson – Boston Medical Center; Nina Lin – Boston Medical Center; Jennifer Snyder-Cappione – Boston University School of Medicine
Thursday, Jun 20
6:15 pm

H. 94 - A Novel Serum Antibody Profiling Assay Reveals a Stratification of Healthy Toddlers into Low, Intermediate and High IgG Responders towards Autoantigens, Infectious Agents, and Vaccine Antigens
Nicolai van Oers, PhD – UT Southwestern Medical Center; Patricia Pichilingue-Reto, MD – UT Southwestern Medical Center; Prithvi Raj, PhD – UT Southwestern Medical Center; Igor Dozmorov, PhD – UT Southwestern Medical Center; Quan-Zhen Li, MD, PhD – UT Southwestern Medical Center; Edward Wakeland, PhD – UT Southwestern Medical Center; Nancy Kelly, MD – Children's Health Dallas; Maria Teresa de la Morena, MD – Pediatrics, U. Washington and Seattle Children's Hospital
Thursday, Jun 20
6:15 pm

H. 95 - Neutrophil subsets and their contribution to immune modulation during pneumococcal pneumonia
Liliana A. Gonzalez – Pontificia Universidad Católica de Chile; Loreani P. Noguera – Pontificia Universidad Catolica de Chile; Valentina P. Sebastian – Pontificia Universidad Catolica de Chile; Isidora Suazo – Pontificia Universidad Catolica de Chile; Barbara M. Schultz – Pontificia Universidad Catolica de Chile; Omar P. Vallejos – Pontificia Universidad Catolica de Chile; Susan M. Bueno – Pontificia Universidad Católica de Chile
Thursday, Jun 20
6:15 pm

H. 96 - Loss of IL6R Causes Immunodeficiency, Atopy, and Abnormal Inflammatory Responses
Sarah Spencer, MBChB MSc MRCP – Department of Medicine, University of Cambridge; William Egner, PhD – Sheffield Teaching Hospitals NHS Foundation Trust; Sevgi Kostel Bal, MD – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Hana Lango Allen, PhD – Department of Haematology, University of Cambridge; Irfan Raza Syed, PhD – Quaid-i-Azam University; Chi Adrian Ma, PhD – National Institute of Allergy and Infectious Diseases; Meltem Gurel, BSc – Cancer Research UK Cambridge Institute; Yuan Zhang, PhD – National Institute of Allergy and Infectious Diseases; Guanping Sun, PhD – National Institute of Allergy and Infectious Diseases; Ruth A Sabroe, MD – Department of Dermatology, Sheffield Teaching Hospitals NHS Trust; Daniel Greene, PhD – Department of Haematology, University of Cambridge; William Rae, MSc – Department of Medicine, University of Cambridge; Tala Shahin, MRes – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Katarzyna Kania, PhD – Cancer Research UK Cambridge Institute; Rico Chandra Ardy, MRes – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Annika Pecchia-Bekkum, MSc – Department of Medicine, University of Cambridge; William P.M. Worrall, BSc – Department of Medicine, University of Cambridge; Jonathan Stephens, PhD – Department of Haematology, University of Cambridge; Matthew Brown, BSc – Department of Haematology, University of Cambridge; Salih Tuna, PhD – Department of Haematology, University of Cambridge; Melanie York, MSc – Sheffield Teaching Hospitals NHS Foundation Trust; Fiona Shackley, MBChB – Sheffield Teaching Hospitals NHS Foundation Trust; Diarmuid Kerrin, BM – Barnsley Hospitals NHS Foundation Trust; Ravishakar Sargur, MD – Sheffield Teaching Hospitals NHS Foundation Trust; Alison Condliffe, PhD – Sheffield Teaching Hospitals NHS Foundation Trust; Hamid Nawaz Tipu, MBBS – Immunology Department, Armed Forces Institute of Pathology; Ernest Turro, PhD – Department of Haematology, University of Cambridge; Simon Tavare, PhD – Herbert and Florence Irving Institute for Cancer Dynamics; Adrian Thrasher, PhD – Molecular and Cellular Immunology Section, UCL Great Ormond Street Institute of Child Health; Duncan Jodrell, PhD – Cancer Research UK Cambridge Institute; Kenneth G.C. Smith, PhD – Department of Medicine, University of Cambridge; Kaan Boztug, PhD – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Joshua D. Milner, PhD – National Institute of Allergy and Infectious Diseases; James E.D. Thaventhiran, PhD – Cancer Research UK Cambridge Institute
Thursday, Jun 20
6:15 pm

H. 97 - Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β
Juan Li – The Rockefeller University; Marco Ritelli – University of Brescia; Cindy Ma – Garvan Institute of Medical Research; Geetha Rao – Garvan Institute of Medical Research; Emilie Corvilain – INSERM U1163; Sophie Cypowyj – The Rockefeller University; Lucie Grodecká – Centre for Cardiovascular Surgery and Transplantation; Romain Lévy – INSERM U1163; Vivien Béziat – INSERM U1163; Lei Shang – The Rockefeller University; Kathryn Payne – Garvan Institute of Medical Research; Danielle Avery – Garvan Institute of Medical Research; Mélanie Migaud – INSERM U1163; Soraya Boucherit – INSERM U1163; Sabri Boughorbel – Sidra Medicine; Salim Bougarn – Sidra Medicine; Andrea Guennoun – Sidra Medicine; Maya Chrabieh – INSERM U1163; Franck Rapaport – The Rockefeller University; Benedetta Bigio – The Rockefeller University; Yuval Itan – The Rockefeller University; Bertrand Boisson – The Rockefeller University; Valérie Cormier-Daire – Imagine Institute; Delfien Syx – Ghent University Hospital; Fransiska Malfait – Ghent University Hospital; Nicoletta Zoppi – University of Brescia; Laurent Abel – INSERM U1163; Tomáš Freiberger – Centre for Cardiovascular Surgery and Transplantation; Nico Marr – Sidra Medicine; Stuart Tangye, PhD – Garvan Institute of Medical Research; Marina Colombi – University of Brescia; Anne Puel – INSERM U1163; Jean-Laurent Casanova – The Rockefeller University
Thursday, Jun 20
6:15 pm

H. 98 - The characteristics of CD8+ T lymphocytes in a family with a novel CD40 ligand mutation
Junghee Shin – Yale University School of medicine; Insoo Kang – Yale University, School of Medicine; Jason Catanzaro – Yale University, Pediatrics; Min Sun Shin – Yale University, School of Medicine; Neil Romberg – Children's hospital of philadelpia; Paula Whittington – Yale University, School of Medicine
Thursday, Jun 20
6:15 pm

H. 99 - A New PIK3CD Gene Variant in APDS
Nina Brodsky, M.D. – Yale; Andrew Rice, MS – Yale; Paul Tyler, BS – Yale; Jean-Marie Carpier, PhD – Yale; Stephen Lanahan, BS – Yale; Gulbu Uzel, M.D. – NIH; Carie Lucas, PhD – Yale
Thursday, Jun 20
6:15 pm

H. 100 - Analysis of Discoid Lupus Erythematosus (DLE) Gene Expression Reveals Dysregulation of Pathogenic Pathways Activated within Infiltrating Cells
Frances Harris – RILITE Research Institute; Sarah Heuer – RILITE Research Institute; Robert Robl – RILITE Research Institute; Prathyusha Bachali – RILITE Research Institute; Adam Labonte, Ph.D. – RILITE Research Institute; Ben F. Chong, M.D. Ph.D. – University of Texas Southwestern Medical Center; Michelle Catalina, Ph.D. – RILITE Research Institute; Peter E. Lipsky, M.D. – RILITE Research Institute; Amrie C. Grammer, Ph.D. – RILITE Research Institute
Thursday, Jun 20
6:15 pm

H. 102 - Targeting CXCR3-mediated T cell recruitment to the skin in Cutaneous Lupus Erythematosus
Dhrumil Patel, BS – UMass Medical School; Colton Garelli, BS – UMass Medical School; Purvi Mande, PhD – UMass Medical School; Kyle J. Gellatly, BS – UMass Medical School; Maggi Ahmed Refat, MD – UMass Medical School; James Strassner, BS – UMass Medical School; Stephanie Moses, BA – UMass Medical School; Evangeline Kim, BA – UMass Medical School; Patrick McDonel, PhD – UMass Medical School; Anthony Coffin-Schmidt, MA – UMass Medical School; Wei Che Ko, MD – UMass Medical School; Mehdi Rashighi-Firoozabadi, MD – UMass Medical School; Manuel Garber, PhD – UMass Medical School; John Harris, MD PhD – UMass Medical School; Ann Marshak-Rothstein, PhD – UMass Medical School; Jillian Richmond, PhD – UMass Medical School
Thursday, Jun 20
6:15 pm

H. 103 - PD-1H (VISTA)-mediated Suppression of Autoimmunity in Systemic and Cutaneous Lupus Erythematosus and its Implication as a Therapeutic Target
Matthew D. Vesely, MD, PhD – Yale School of Medicine; Xue Han, PhD – Yale University; Miguel F. Sanmamed, MD – Yale University; Ti Badri, MS – Yale University; Francesc Lopez-Giraldez, PhD – Yale University; Patricia Gaule, PhD – Yale Univeristy; Ala Nassar, PhD – Yale University; Linghua Zheng, PhD – Yale University; Tae Kon Kim, MD, PhD – Yale University; Gilbert Moeckel, MD, PhD – Yale University; Jennifer McNiff, MD – Yale University; Lieping Chen, MD, PhD – Yale University
Thursday, Jun 20
6:15 pm

H. 104 - STING Activation Cell-Intrinsically Modulates CD4 T Cell Differentiation and Enhances the Antitumor Activity of Th1 and Th9 Cells
Isis Benoit-lizon – INSERM U1231; Lionel Apetoh – INSERM U1231
Thursday, Jun 20
6:15 pm

H. 105 - Uncovering heterogeneity and dynamics of human tumor infiltrating T cells to identify orthogonal mechanisms and potential novel targets for cancer immunotherapy
Xin Yu – Amgen, inc.; Aeryon Kim – Amgen inc.; Chia-Jung Han – Amgen inc.; Lei Zhang – Peking University; Ian Driver – Amgen inc.; Aleksandra Olow – Amgen inc.; Zemin Zhang – Peking University; Jackson Egen – Amgen inc.; Wenjun Ouyang – Amgen inc.
Thursday, Jun 20
6:15 pm

H. 106 - Neuropilin-1 is a T cell memory checkpoint limiting long-term anti-tumor Immunity
Chang Liu, PhD – Department of Immunology, School of Medicine, University of Pittsburgh; Ashwin A.A. Somasundaram, PhD – University of Pittsburgh; Sasikanth Manne, MSc – Penn Institute for Immunology, University of Pennsylvania; Andrea Szymczak-Workman, PhD – Department of Immunology, University of Pittsburgh; Angela Gocher, PhD – University of Pittsburgh; Tullia Bruno, PhD – University of Pittsburgh; E. John Wherry, PhD – Penn Institute for Immunology, University of Pennsylvania; Creg Workman, PhD – University of Pittsburgh; Dario Vignali, PhD – University of Pittsburgh
Thursday, Jun 20
6:15 pm

H. 107 - Single-cell lymphocyte heterogeneity in advanced Cutaneous T-Cell Lymphoma skin tumors
Patrizia Fuschiotti – University of Pittsburgh; Alyxzandria Gaydosik – University PIttsburgh; Tracy Tabib – University Pittsburgh; Larisa Geskin – Columbia University; James Conway – University of Pittsburgh; Robert Lafyatis – University Pittsburgh
Thursday, Jun 20
6:15 pm

H. 108 - IL-35+ B cells establish immunosuppressive network in pancreatic ductal adenocarcinoma.
Bhalchandra Mirlekar – Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; Yuliya MIRLEKAR – Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Thursday, Jun 20
6:15 pm

H. 109 - Antigen Cross-Presentation Promotes Development of ICB non-Responsive CD8 T Cells
Ardiana Moustaki, PhD – St. Jude Children's Research Hospital; Shanta Alli, PhD – St. Jude Children's Research Hospital; Sara M. Federico, MD – St. Jude Children's Research Hospital; Elizabeth Stewart, MD – St. Jude Children's Research Hospital; Shannon Boi, PhD – St. Jude Children's Research Hospital; Jeremy Crawford, PhD – St. Jude Children's Research Hospital; Anthony Zamora, PhD – St. Jude Children's Research Hospital; Paul Thomas, PhD – St. Jude Children's Research Hospital; Ben Youngblood, PhD – St. Jude Children's Research Hospital
Thursday, Jun 20
6:15 pm

H. 110 - The Anti-tumor Effect of Trastuzumab in HER2+ Breast Cancer is Principally Mediated by Antibody-Dependent Phagocytosis of Tumor-Associated Macrophages and can be Significantly Enhanced by CD47 Innate Immune Blockade
Li-Chung Tsao – Duke University; Herbert K. Lyerly – Duke University; Zachary Hartman – Duke University
Thursday, Jun 20
6:15 pm

H. 111 - Pharmacological inhibition of RORγt preserves human Th17-like regulatory T cell stability
Dominic A. Boardman, PhD – Department of Surgery, University of British Columbia; Rosa V. Garcia – Department of Surgery, University of British Columbia; Sabine Ivison, PhD – Department of Surgery, University of British Columbia; Brian Bressler, M.D. – Department of Medicine, University of British Columbia; Murali Dhar, PhD – Bristol-Myers Squibb; Qihong Zhao, M.D., Ph.D. – Bristol-Myers Squibb; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia
Thursday, Jun 20
6:15 pm

H. 112 - Metabolic targeting of microbiota-reactive CD4 T memory cells as an immunotherapy for inflammatory bowel disease
Qing Zhao – The University of Alabama at Birmingham; Lennard W. Duck – The University of Alabama at Birmingham; Charles O. Elson – The University of Alabama at Birmingham
Thursday, Jun 20
6:15 pm

H. 113 - Analysis of APL expression in an animal model of chronic colitis
Takashi Nagaishi, MD, PhD – Tokyo Medical and Dental University; Yudai Kojima, MSc – Tokyo Medical and Dental University; Daiki Yamada, MD – Tokyo Medical and Dental University; Taro Watabe, MD, PhD – Tokyo Medical and Dental University; Naoya Tsugawa, MD – Tokyo Medical and Dental University; Nisha Jose, MSc – Tokyo Medical and Dental University; Akinori Hosoya, MD – Tokyo Medical and Dental University; Masahiro Suzuki, MD, PhD – Tokyo Medical and Dental University; Michio Onizawa, MD, PhD – Tokyo Medical and Dental University; Mamoru Watanabe, MD, PhD – Tokyo Medical and Dental University
Thursday, Jun 20
6:15 pm

H. 114 - c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis
Sascha Rutz – Genentech; Christian Neumann, PhD – Charite Berlin; Alexander Scheffold, PhD – University Kiel
Thursday, Jun 20
6:15 pm

H. 115 - Combined Analysis of Flagellin-Specific Immune Responses and Microbiome Diversity in IBD Patients
Daniel J. Lisko, MSc – University of British Columbia; Laura Cook, PhD – University of British Columbia; May Q. Wong, BSc – University of British Columbia; Brian Bressler, M.D. – Department of Medicine, University of British Columbia; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia; Theodore Steiner, MD – University of British Columbia
Thursday, Jun 20
6:15 pm

H. 116 - CRISPR/Cas9-based platforms for therapeutic target identification and validation
Rui Wang, Sr Scientist III – Abbvie
Thursday, Jun 20
6:15 pm

H. 117 - Evaluation of Different Lactobacillus Strains on the Treatment of Inflammatory Bowel Disease in a Murine Model
Dominic Poulin, MSc – Charles River; Wayne Finlayson, BSc (Hons), PhD – Servatus Biopharmaceuticals; Kylie Ralston, BSc (Hons) – Servatus Biopharmaceuticals; Nicolas Pichon, PhD – Servatus Biopharmaceuticals; Samantha Coulson, PhD – Servatus Biopharmaceuticals; Christopher DeBakker, PhD – Servatus Biopharmaceuticals; Rana Samadfam, MSc, PhD, DABT – Charles River
Thursday, Jun 20
6:15 pm

H. 118 - IL-12 and mucosal CD14+ monocyte-like cells induce IL-8 in colonic memory CD4+ T cells of patients with Ulcerative colitis but not Crohn’s disease
Laurence Chapuy – CRCHUM University of Montreal; Marwa Bsat – CRCHUM University of Montreal; Amélie Therrien – CRCHUM University of Montreal; Manuel Rubio – CRCHUM University of Montreal; Audrey Weber – CHUM; Mickael Bouin – CHUM; Geneviève Soucy – CHUM; Sisi Sarkizova – Harvard Medical School,; Alexandra-Chloe Villani – Broad Institute of MIT and Harvard, Center for Immunology and Inflammatory Diseases Massachusetts General Hospital; Marika Sarfati – CRCHUM University of Montreal
Thursday, Jun 20
6:15 pm

H. 119 - Modelling Inflammatory Bowel Disease using a Translational Assay Platform
Louise S. Brackenbury, PhD – Charles River Laboratories; Tommaso Iannitti, PhD – Charles River Laboratories; Louise Harvey; Sophie Matthews; Tina Rea-Davies; Sally Woodman; Alexander Rew; Rhiannon Jenkinson, PhD – Charles River Portishead
Thursday, Jun 20
6:15 pm

H. 120 - Molecular Characterization of Colonic MAIT Cells in Crohn’s Disease
Andrew J. Konecny, BS – Benaroya Research Institute at Virginia Mason; James D. Lord, MD PhD – Benaroya Research Institute at Virginia Mason
Thursday, Jun 20
6:15 pm

H. 121 - Potential contribution of NK cells to the Immunopathogenesis of Crohn disease
Suzanne Samarani – CHU Ste-Justine Research Center/University of Montreal; Colette Deslandres – CHU Saint Justine Hospital; Devendra Amre – CHU Ste-Justine Research Center/University of Montreal; Ali Ahmad – CHU Ste-Justine Research Center/University of Montreal
Thursday, Jun 20
6:15 pm

H. 122 - Smad7 controls immunoregulatory PDL2/1-PD1 signaling in intestinal inflammation
Lucien P. Garo, III, B.A. – Brigham and Women's Hospital and Harvard Medical School; Amrendra Ajay, PhD – Brigham and Women's Hospital and Harvard Medical School; Vanessa Beynon, MD – Brigham and Women's Hospital and Harvard Medical School; Chantal Kuhn, PhD – Brigham and Women's Hospital and Harvard Medical School; Mai Fujiwara, PhD – Brigham and Women's Hospital and Harvard Medical School; Radhika Raheja, PhD – Brigham and Women's Hospital and Harvard Medical School; Howard Weiner, MD – Brigham and Women's Hospital, Harvard Medical School; Murugaiyan Gopal, PhD – Brigham and Women's Hospital and Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 123 - Neutrophil maturation and their response to infectious pathogens are regulated by microbiota
Anastasia Petenkova, PhD – Brigham and Women's Hospital; Abirami Kugadas, PhD – Brigham and Women's Hospital; Jennifer Geddes-McAlister, PhD – University of Guelph; Michael Mansour, MD, PhD – Massachusetts General Hospital; David Sykes, MD, PhD – Massachusetts General Hospital; Mihaela Gadjeva, PhD – Brigham and Women's Hospital
Thursday, Jun 20
6:15 pm

H. 124 - Association of RIG-I and TLR4 Pathway Suppression with Increased Disease Severity in Critically Ill Children with Influenza Pneumonia
Tanya Novak, PhD – Boston Children’s Hospital and Harvard Medical School; Mark W. Hall, MD, FAAP, FCCM – Nationwide Children's Hospital and The Ohio State University College of Medicine; Margaret Newhams, MPH – Boston Children’s Hospital; Douglas McDonald, MD, PhD – Boston Children's Hospital, Harvard Medical School; Helen Su, MD, PhD – NIH/NIAID; Adrienne G. Randolph, MD, MS, FAAP – Boston Children’s Hospital and Harvard Medical School
Thursday, Jun 20
6:15 pm

H. 126 - Intracellular Calcium Signals and Chemotaxis are Altered in Human Neutrophils with Aging
Maria de los Angeles. Vázquez Prieto, Clinic Chemistry – Universidad Veracruzana; Nallely Lascurais Santamaria – Universidad Veracruzana; Nilda Belén Fernández Eufrasio, Doctor – Universidad Veracruzana; Adriana Sumoza-Toledo, PhD – Universidad Veracruzana
Thursday, Jun 20
6:15 pm

H. 127 - Human tolerogenic dendritic cells used in a phase I/II clinical trial regulate immune responses through lactate synthesis
Eros Marin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Laurence Bouchet-Delbos – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Véronique Nerrière-Daguin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Gilles Blancho, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Claire Pecqueur – Centre de Recherche en Cancérologie et Immunologie Nantes-Angers, UMR1232 INSERM, Université de Nantes; Maria-Cristina Cuturi – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Aurelie Moreau – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes
Thursday, Jun 20
6:15 pm

H. 128 - Association between cytotoxic T cells CD8+CD28- in peripheral blood and histological diagnosis of renal transplant biopsy
Sabine Le Bot – Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes; Sophie Brouard, DVM, PhD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Magali Giral, MD, PhD – CRTI UMR1064, INSERM, Université de Nantes; Karine Renaudin, MD – Service d'anapathologie CHU Hotel Dieu Nantes, Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, Nantes, France; Thomas Goronflot – Laboratoire de biostatistique CHU Hotel Dieu Nantes; Florent Delbos, PhD – Laboratoire HLA, Etablissement Français du Sang Centre Pays-de-le-Loire; Marie RImbert – Laboratoire d'immunologie CHU Hotel Dieu Nantes
Thursday, Jun 20
6:15 pm

H. 129 - Corticosteroid-Resistant Severe Acute GVHD Promptly Rescued By Plasma-Transfusion-Mediated Donor HLA-targeted Serotherapy
Julien Zuber – Paris Descartes University; Olivia Boyer – Paris Descartes University; Benedicte Neven – Paris Descartes University; Romain Berthaud – Paris Descartes University; Mélissa Ould Rabah – Paris Descartes University; Isabelle Jollet – Etablissement Français du Sang; Virginie Renac – Etablissement Français du Sang; France Pirenne – Etablissement Français du Sang; Sylvie Gross – Etablissement Français du Sang; Rachid Djoudi – Etablissement Français du Sang; Pierre Tiberghien – former head of the Etablissement du Sang; Jean Luc Taupin – Paris Diderot University; Stephane Blanche – Paris Descartes University; Remi Salomon – Paris Descartes University
Thursday, Jun 20
6:15 pm

H. 130 - Sustained engraftment and protein secretion using gene-edited human B cells in humanized mouse models
Richard G. James, PhD – Seattle Children's Research Institute; King Hung, BS – Seattle Children's Research Institute; Iram Khan, PhD – Seattle Children's Research Institute; Tingting Zhang, PhD – Seattle Children's Research Institute; Rene Cheng, BS – University of Washington; Swati Singh, BS – Seattle Children's Research Institute; Emmaline Suchland, BS – Seattle Children's Research Institute; Chester Jacobs, BS – Seattle Children's Research Institute; Matthew Macquivey, BS – Seattle Children's Research Institute; Claire Stoffers, BS – Seattle Children's Research Institute; David Rawlings, MD – Seattle Children's Research Institute
Thursday, Jun 20
6:15 pm

H. 131 - Monitoring T cell responses toward the Streptococcus pyogenes Cas9 nuclease
Dimitrios Wagner, medical student – Charité Universitaetsmedizin Berlin; Marie Luetke-Eversloh – Charité Universitaetsmedizin Berlin; Leila Amini – Charité Universitaetsmedizin Berlin; Desiree J. Wendering, M.Sc. Molecular Medicine – Insitute for Medical Immunology, Charite; Lisa-Marie Burkhardt – Charité Universitaetsmedizin Berlin; Levent Akyuez – Charité Universitaetsmedizin Berlin; Holger Wenschuh, PhD – JPT Peptide Technologies GmbH; Petra Reinke – Charité Universitaetsmedizin Berlin; Hans-Dieter Volk, M.D./Ph.D. – Charité Universitaetsmedizin Berlin; Michael Schmueck-Henneresse, Ph.D. – Charité Universitaetsmedizin Berlin
Thursday, Jun 20
6:15 pm

H. 132 - Anti-inflammatory effect of honey on pulmonary inflammation associated with neutrophil by lipopolysaccharide (LPS) in mice
Minoru Takeuchi – Kyoto Sangyo University
Thursday, Jun 20
6:15 pm

H. 133 - Anti-TNF Treatment Delays Human CD4+ T-cell Activation, Maturation and Proliferation, but does not Confer an Anergic or Suppressive Phenotype
Giovanni AM. Povoleri – King's College London; Sylvine Lalnunhlimi – King's College London; Kathryn Steel – King's College London; Shweta Agrawal – King's College London; Michael L. Ridley – Kings College London; Sharam Kordasti – King's College London; Ceri A. Roberts – NHS; Leonie S. Taams – King's College London
Thursday, Jun 20
6:15 pm

H. 134 - Aurora Kinase A signaling alters tumor microenvironment to shape tumor evolution in therapeutic resistance
Khyati N. Shah – UCSF; Sourav Bandyopadhyay – UCSF
Thursday, Jun 20
6:15 pm

H. 135 - CD19+ IL-10+ changes after bacterial suspension treatment in patients with allergic conjunctivitis.
Israel Casanova-Mendez, Sr. – Institute of Ophthalmology; Alberto Salazar – Institute of Ophthalmology; Henry Velázquez-Soto – Institute of Ophthalmology; Quintana Guillermo – instituto de oftalmologia; Pacheco Mayte – instituto de oftalmologia conde de valenciana; Maria C Jimenez-Martinez – Institute of Ophthalmology
Flow Cytometry Course (included in FOCIS 2019 registration)
Wednesday, Jun 19
3:15 pm

Flow Cytometry Course
Location: Wellesley, 3rd Floor
Thursday, Jun 20
3:15 pm

Flow Cytometry Course
Location: Wellesley, 3rd Floor
FOCISed Courses
Monday, Jun 17
7:30 am

Systems Immunology Course (pre-meeting course, separate registration required)
Location: Salon G, 4th Floor
Emanuele de Rinaldis, PhD; Magnus Fontes, PhD
Monday, Jun 17
8:00 am

Basic Immunology in Medicine: Update 2019 Course (pre-meeting course, separate registration required)
Location: Salon F, 4th Floor
Shiv Pillai, MD PhD – Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Department of Medicine, Harvard University, Cambridge, MA, USA; Andrew Lichtman, MD, PhD; Abul Abbas, MD
Tuesday, Jun 18
8:00 am

Big Data ImmPort Workshop (pre-meeting workshop, separate registration required)
Location: Provincetown, 4th Floor
Tuesday, Jun 18
8:00 am

Cancer Immunity & Immunotherapy Course (pre-meeting course, separate registration required)
Location: Salon A-C, 4th Floor
Keynote Address
Tuesday, Jun 18
5:30 pm

ER Stress Reprograms the Tumor Microenvironment
Location: Salon FG, 4th Floor
Laurie H. Glimcher, MD – Dana-Farber Cancer Institute
Wednesday, Jun 19
5:30 pm

Organoids as models of human disease
Location: Salon FG, 4th Floor
Hans Clevers, MD, PhD – University Hospital Utrecht
Thursday, Jun 20
5:30 pm

Standing on the Shoulders of Mice: Rebooting Human Immunology
Location: Salon FG, 4th Floor
Mark M. Davis, PhD – Stanford University
Lunch Programs
Wednesday, Jun 19
11:30 am

Industry Workshop: Tessa Therapeutics
Location: Salon FG, 4th Floor
Sponsored By:
Wednesday, Jun 19
11:30 am

Industry Workshop: Beckman Coulter
Location: Salon H-K, 4th Floor
Sponsored By:
Wednesday, Jun 19
11:30 am

Industry Workshop: BioLegend
Location: Salon A-D, 4th Floor
Sponsored By:
Thursday, Jun 20
11:45 am

Engaging with the Immune Tolerance Network (ITN)
Location: Salon FG, 4th Floor
Sponsored By:
Thursday, Jun 20
11:45 am

Who’s Reading Your Application? How Study Sections are Created
Location: Salon H-K, 4th Floor
Sponsored By: National Institutes of Health
Thursday, Jun 20
11:30 am

RESTORE Health by Advanced Therapies - Opportunities & Challenges
Location: Salon A-D, 4th Floor
Sponsored By: RESTORE
Member Reception
Wednesday, Jun 19
7:30 pm

FOCIS Member Reception (FOCIS Members only)
Location: 3rd Floor Atrium Lounge
Sponsored By:
Member Society Symposia (included in FOCIS 2019 registration)
Tuesday, Jun 18
8:00 am

Developing Therapeutic Antibodies for Successful Entry into the Clinic
Location: Simmons, 3rd Floor
Hosted By:
Tuesday, Jun 18
8:00 am

From Pathogenesis to Immunotherapy over the Atlantic
Location: Salon HI, 4th Floor
Hosted By:
Tuesday, Jun 18
8:00 am

Imaging Immune Response to Transplanted Organs
Location: Salon JK, 4th Floor
Hosted By:
Tuesday, Jun 18
8:00 am

Immune Aberrations in Human Disease
Location: Salon D, 4th Floor
Hosted By:
Tuesday, Jun 18
8:00 am

Understanding Human Immune Response Variability from Population to Single Cell Levels
Location: Wellesley, 3rd Floor
Hosted By:
Tuesday, Jun 18
1:00 pm

Glycans in Immune Homeostasis and Inflammation
Location: Salon HI, 4th Floor
Hosted By:
Tuesday, Jun 18
1:00 pm

Mobilizing Mucosal Immunology
Location: Wellesley, 3rd Floor
Hosted By:
Tuesday, Jun 18
1:00 pm

Regulatory Mechanisms of Innate Immune Responses that Influence Transplantation, Autoimmune Disease and Cancer
Location: Simmons, 3rd Floor
Hosted By:
Tuesday, Jun 18
1:00 pm

Single Cell Analytics of Autoimmune Target Tissue to Elucidate Disease Pathogenesis and Treatment Targets
Location: Provincetown, 4th Floor
Hosted By:
Tuesday, Jun 18
1:00 pm

Viral Mechanisms in Rheumatic Disease
Location: Salon JK, 4th Floor
Hosted By:
Plenary
Wednesday, Jun 19
8:00 am

Role of Antigen Presentation in Response to Immune Checkpoint Blockade
Location: Salon FG, 4th Floor
F. Stephen Hodi, MD
Wednesday, Jun 19
8:30 am

Development of TLR9 Agonists for Cancer Immunotherapy
Location: Salon FG, 4th Floor
Bob Coffman, PhD – Dynavax
Wednesday, Jun 19
9:00 am

Redirecting T-cells for Cancer Immunotherapy using Next Generation Bispecific Antibodies and Fusion Proteins
Location: Salon FG, 4th Floor
Pablo Umaña, PhD – Roche Innovation Center Zurich, pRED, Roche
Wednesday, Jun 19
10:00 am

Immunometabolic checkpoints of inflammation
Location: Salon FG, 4th Floor
Vishwa Deep Dixit, DVM, PhD – Yale University
Wednesday, Jun 19
10:30 am

Signaling Circuits and Metabolic Control of Adaptive Immunity
Location: Salon FG, 4th Floor
Hongbo Chi, PhD – St. Jude Children's Research Hospital
Wednesday, Jun 19
11:00 am

Dissecting Tumor metabolism from Immunometabolism to enhance immunotherapy for Cancer
Location: Salon FG, 4th Floor
Jonathan Powell, MD, PhD – Johns Hopkins Medicine
Thursday, Jun 20
8:00 am

The γc family of cytokines and fine-tuning their signals
Location: Salon FG, 4th Floor
Warren Leonard, MD – National Heart, Lung, and Blood Institute
Thursday, Jun 20
8:30 am

Effects of Anti-CD3 Antibody in Relatives at Risk for Type 1 Diabetes. The Trialnet TN10 Study
Location: Salon FG, 4th Floor
Kevan Herold, MD – Yale Univeristy
Thursday, Jun 20
9:00 am

Inflammation and Atherothrombosis: From Theory to Proven Intervention
Location: Salon FG, 4th Floor
Peter Libby, MD – Brigham and Women’s Hospital
Thursday, Jun 20
10:00 am

Tissue T cell phenotypes in human autoimmunity
Location: Salon FG, 4th Floor
Deepak Rao, MD, PhD – Brigham and Women's Hospital/Harvard Medical School
Thursday, Jun 20
10:30 am

Microbiota, intestinal permeability and gut-liver axis
Location: Salon FG, 4th Floor
Maria Rescigno, PhD – Humanitas University
Thursday, Jun 20
11:00 am

High resolution analysis of human tissue resident T cells in diverse sites
Location: Salon FG, 4th Floor
Donna Farber, PhD – Columbia University
Friday, Jun 21
8:00 am

Single-cell epigenomics in cancer immunotherapy
Location: Salon FG, 4th Floor
Ansuman Satpathy, MD, PhD – Stanford University School of Medicine
Friday, Jun 21
8:30 am

Three-dimensional gene regulatory architectures reveal causal, disease-associated variants and genes at inflammatory GWAS loci
Location: Salon FG, 4th Floor
Andrew D. Wells, PhD – University of Pennsylvania
Friday, Jun 21
9:00 am

Epigenetic regulation of T cell differentiation
Location: Salon FG, 4th Floor
Benjamin Youngblood, PhD – St. Jude Children's Research Hospital
Friday, Jun 21
10:00 am

VISTA regulation of the tumor microenvironment
Location: Salon FG, 4th Floor
Randolph Noelle, PhD – Dartmouth College
Friday, Jun 21
10:30 am

The Biology of PD-1 Checkpoint Blockade
Location: Salon FG, 4th Floor
Arlene H. Sharpe, MD, PhD – Harvard Medical School
Friday, Jun 21
11:00 am

Reverse translation using clinical genomics reveals mechanisms of resistance to immunotherapies
Location: Salon FG, 4th Floor
Sanjeev Mariathasan, PhD
Thematic
Wednesday, Jun 19
1:00 pm

Clonal hematopoiesis and myeloid cells in human disease
Location: Salon FG, 4th Floor
Kenneth Walsh, PhD – University of Virginia
Wednesday, Jun 19
1:25 pm

The role of CD47 in the battlefield of Borrelia-host immune modulation in Lyme disease
Location: Salon FG, 4th Floor
Michal C. Tal, PhD – Stanford University; Maia Shoham, BSc – Stanford University; Balyn Zaro, PhD – Stanford University; Maxim Markovic, BSc – Stanford University; Irving Weissman, PhD – Stanford University
Wednesday, Jun 19
1:40 pm

Getting at disease mechanism through studies on lipoprotein trafficking
Location: Salon FG, 4th Floor
Gwendalyn J. Randolph, PhD – Washington University
Wednesday, Jun 19
2:05 pm

Context-Specific Regulation of Monocyte Surface and Soluble IL7R Expression by a Genetic Risk Allele
Location: Salon FG, 4th Floor
Hussein Al-Mossawi, BA, MA (Oxon), BMBCh, MRCP, DPhil – University of Oxford; Nicole Yager, BSc DPhil – University of Oxford; Chelsea Taylor, BSc – University of Oxford; Sara Danielli, BSc – University of Oxford; Elise Mahe, BSc PhD – University of Oxford; Paul Bowness, BSc MA DPhil FRCP – University of Oxford; Benjamin Fairfax, BSc PhD MRCP – University of Oxford
Wednesday, Jun 19
2:20 pm

Adding New Pieces to the Human Lupus Puzzle
Location: Salon FG, 4th Floor
Virginia Pascual – Drukier Institute for Children’s Health, Weill Cornell Medicine
Wednesday, Jun 19
1:00 pm

Overcoming rejection of cardiac xenograft
Location: Salon H-K, 4th Floor
Muhammad M. Mohiuddin, MD – University of Maryland School of Medicine
Wednesday, Jun 19
1:25 pm

Dissecting and Reconstructing the Human Thymus-Designing Roadmaps and Building Blocks for Functional Thymic Organoids
Location: Salon H-K, 4th Floor
Hui Gai, MD – Stanford University; Yogendra Verma, MS – Stanford University; Ellie Kim, BS – Stanford University; Sarah Heilshorn, PhD – Stanford University; Ken Weinberg, MD – Stanford Uiversity; Georg Hollander, MD – University of Oxford; Maria Grazia Roncarolo, MD PhD – Stanford University; Vittorio Sebastiano, PhD – Stanford University; Katja Gabriele. Weinacht, MD PhD – Department of Pediatrics, Stem Cell Transplantation, at the Lucile Salter Packard Children’s Hospital, Stanford school of medicine, Stanford, CA, USA
Wednesday, Jun 19
2:05 pm

Generation of CD8+ and CD4+ Regulatory T Cells from Human Pluripotent Stem Cells
Location: Salon H-K, 4th Floor
Lea Flippe – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; Anne Gaignerie – iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Séverine Bézie – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Ignacio Anegon – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology", Nantes, France.; Laurent David – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France, iPSC corefacility, University of Nantes; INSERM UMS 016; CNRS 3556; CHU de Nantes, France; Carole Guillonneau – Centre de Recherche en Transplantation et Immunologie UMR 1064, Inserm, Nantes, France; Institut de Transplantation Urologie Néphrologie, Nantes, France; LabEx IGO
Wednesday, Jun 19
2:20 pm

Interspecies Chimeras for Generation of Functional Organs
Location: Salon H-K, 4th Floor
Hiromitsu Nakauchi, MD, PhD – Stanford University
Wednesday, Jun 19
2:20 pm

Strategies for the Success of Xenotransplantation
Location: Salon H-K, 4th Floor
Kazuhiko Yamada, MD, PhD – Columbia Center for Translational Immunology, Department of Surgery, Columbia University
Thursday, Jun 20
1:00 pm

Humanized mice to study cancer-immune system interface
Location: Salon FG, 4th Floor
Karolina Palucka, MD, PhD – Baylor Research Institute
Thursday, Jun 20
1:25 pm

Personalized Immune Mice Model Genetically-Predetermined Immune Dysregulation of Patients with T1D
Location: Salon FG, 4th Floor
Mohsen Khosravi-Maharlooe, MD/MSc – Columbia University; Nichole Danzl, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Chiara Borsotti, Ph.D. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Sean Campbell R., MD/PhD – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Aleksandar Obradovic – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Todd M. Brusko, Ph.D. – Department of Pathology, Immunology, and Laboratory Medicine, University of Florida; Kortney Rogers, B.S. – Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center; Robin Goland, MD – Columbia University; Sarah Pollak – Columbia University; Robert Winchester, MD – Columbia University; David G. Savage, MD – Columbia University; Megan Sykes, M.D. – Columbia Center for Translational Immunology, Department of Medicine; Department of Microbiology & Immunology; Department of Surgery, Columbia University Medical Center
Thursday, Jun 20
1:40 pm

Humanized Mouse Models of Organ Transplantation
Location: Salon FG, 4th Floor
Jordan Pober, MD, PhD – Yale University
Thursday, Jun 20
2:05 pm

Sustained engraftment and protein secretion using gene-edited human B cells in humanized mouse models
Location: Salon FG, 4th Floor
Richard G. James, PhD – Seattle Children's Research Institute; King Hung, BS – Seattle Children's Research Institute; Iram Khan, PhD – Seattle Children's Research Institute; Tingting Zhang, PhD – Seattle Children's Research Institute; Rene Cheng, BS – University of Washington; Swati Singh, BS – Seattle Children's Research Institute; Emmaline Suchland, BS – Seattle Children's Research Institute; Chester Jacobs, BS – Seattle Children's Research Institute; Matthew Macquivey, BS – Seattle Children's Research Institute; Claire Stoffers, BS – Seattle Children's Research Institute; David Rawlings, MD – Seattle Children's Research Institute
Thursday, Jun 20
2:20 pm

Humanized mice as dynamic models of early B cell tolerance checkpoints
Location: Salon FG, 4th Floor
Eric Meffre, PhD – Yale School of Medicine
Thursday, Jun 20
1:00 pm

Human T Cell Responses in Allergy and Immunotherapy
Location: Salon H-K, 4th Floor
Erik R. Wambre, PhD – Benaroya Research Institute
Thursday, Jun 20
1:25 pm

Effective Treatment of Experimental Asthma by Lung-restricted Inhibition of Janus Kinase 1
Location: Salon H-K, 4th Floor
Nico Ghilardi – Genentech
Thursday, Jun 20
1:40 pm

Understanding human IL33 expression using BAC reporter mice
Location: Salon H-K, 4th Floor
Anne I. Sperling, Committee on Immunology, Department of Medicine Section of Pulmonary and Critical Care – University of Chicago
Thursday, Jun 20
2:05 pm

Diminished Long-Term Outcome in Large Phase 2 Study of Peanut Immunotherapy
Location: Salon H-K, 4th Floor
R. Sharon Chinthrajah, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Natasha Purington, MS – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Sandra Andorf, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Andrew Long, PharmD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Katherine L. O’Laughlin, MN – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Shu-Chen Lyu, MSc – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Monali Manohar, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Scott D. Boyd, MD – Department of Pathology, Stanford University School of Medicine, Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research; Robert Tibshirani, PhD – Department of Biomedical Data Sciences, Stanford University, Department of Statistics, Stanford University; Holden T. Maecker, PhD – Stanford University; Marshall Plaut, MD – National Institute of Allergy and Infectious Diseases; Kaori Mukai, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine, Stanford; Mindy Tsai, DMSc – Department of Pathology, Stanford University School of Medicine; Manisha Desai, PhD – Quantitative Sciences Unit, Stanford University School of Medicine; Stephen J. Galli, MD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research, Department of Pathology, Stanford University School of Medicine, Department of Microbiology and Immunology, Stanford University School of Medicine; Kari C. Nadeau, MD, PhD – Stanford University, Department of Medicine - Sean N Parker Center for Allergy and Asthma Research
Thursday, Jun 20
2:20 pm

Immunottherapeutic Approaches to Treat IgE-mediated Food Allergy
Location: Salon H-K, 4th Floor
Hugh A. Sampson, MD – Mount Sinai School of Medicine
Thursday, Jun 20
3:15 pm

Neutrophil subsets and their contribution to immune modulation during pneumococcal pneumonia
Location: Salon H-K, 4th Floor
Susan M. Bueno – Pontificia Universidad Católica de Chile; Liliana A. Gonzalez – Pontificia Universidad Católica de Chile; Loreani P. Noguera – Pontificia Universidad Catolica de Chile; Valentina P. Sebastian – Pontificia Universidad Catolica de Chile; Isidora Suazo – Pontificia Universidad Catolica de Chile; Barbara M. Schultz – Pontificia Universidad Catolica de Chile; Omar P. Vallejos – Pontificia Universidad Catolica de Chile
Thursday, Jun 20
3:30 pm

Single-cell RNA-sequencing of human microglia reveals subtype-specific association with neurological disorders
Location: Salon H-K, 4th Floor
Marta Olah, PhD – Columbia University Medical Center; Vilas Menon, PhD – Columbia University Medical Center; Mariko Taga, PhD – Columbia University Medical Center; Naomi Habib, PhD – Hebrew University of Jerusalem; Wassim Elyaman, PhD – Columbia University Medical Center; Elizabeth Bradshaw, PhD – Columbia University Medical Center; David Bennett, MD – Rush University Medical Center; Philip De Jager, MD, PhD – Columbia University Medical Center
Thursday, Jun 20
3:45 pm

Immune Atlas of Second Trimester Human Intestine, Liver and Spleen
Location: Salon H-K, 4th Floor
Liza Konnikova, MD, PhD – UPMC Childrens Hospital of Pittsburgh; Stephanie Stras, BA – UPMC Childrens Hospital of Pittsburgh; Lael Werner, PhD – Edmond and Lily Safra Children's Hospital; Jessica Toothaker, BA – University of Pittsburgh; Oluwabunmi Olaloye, MD – UPMC Childrens Hospital of Pittsburgh; Austin Oldham – University of Pittsburgh; Dror Shouval, MD – Edmond and Lily Safra Children's Hospital
Thursday, Jun 20
4:00 pm

Estrogen induction of Interstital Lung Disease is mediated through PD-1+Th17 cell-dependent and -independent signaling pathways
Location: Salon H-K, 4th Floor
Wonder Drake – Vanderbilt University School of Medicine; Ozioma Chioma – Vanderbilt University Medical Center; Natalie Hassell – Vanderbilt University; Kenny Abel – Vanderbilt University Medical Center; Lindsay Celada – Vanderbilt University Medical Center; Dawn Newcomb – Vanderbilt University School of Medicine
Thursday, Jun 20
4:15 pm

Metabolic targeting of microbiota-reactive CD4 T memory cells as an immunotherapy for inflammatory bowel disease
Location: Salon H-K, 4th Floor
Qing Zhao – The University of Alabama at Birmingham; Lennard W. Duck – The University of Alabama at Birmingham; Charles O. Elson – The University of Alabama at Birmingham
Thursday, Jun 20
4:30 pm

BTLA Stimulation Protects Against Atherosclerosis by Regulating Follicular B cells
Location: Salon H-K, 4th Floor
Amanda Foks – Leiden University, Leiden Academic Centre for Drug Research; Hidde Douna – Leiden University, Leiden Academic Centre for Drug Research; Jacob Amersfoort – Leiden University, Leiden Academic Centre for Drug Research; Frank Schaftenaar – Leiden University, Leiden Academic Centre for Drug Research; Marie Depuydt – Leiden University, Leiden Academic Centre for Drug Research; Hideo Yagita – Department of Immunology, Juntendo University School of Medicine; Christoph Binder – Department of Laboratory Medicine, Medical University of Vienna; Ilze Bot – Leiden University, Leiden Academic Centre for Drug Research; Johan Kuiper – Leiden University, Leiden Academic Centre for Drug Research
Thursday, Jun 20
4:45 pm

Graft GD T-Cell Receptor Sequencing Identifies Public Clonotypes Associated to HSCT Efficacy in AML Patients and Unravels CMV Impact on Repertoire Distribution
Location: Salon H-K, 4th Floor
Lucas CM. Arruda – Karolinska Institutet, CLINTEC; Ahmed Gaballa – Karolinska Institutet, CLINTEC; Michael Uhlin, PhD – Karolinska Institute, CLINTEC
Thursday, Jun 20
5:00 pm

H. 89 - A New Specific Promoter to Control Chimeric Antigen Receptor Expression Allow Long Lasting CAR Therapy using Hematopoietic
Location: Salon H-K, 4th Floor
Aurélien Colamartino – CHU Sainte-Justine Research Center, Department of Microbiology and Immunology, University of Montreal