Pharmacological inhibition of RORγt preserves human Th17-like regulatory T cell stability Location: Salon FG, 4th Floor Dominic A. Boardman, PhD – Department of Surgery, University of British Columbia; Rosa V. Garcia – Department of Surgery, University of British Columbia; Sabine Ivison, PhD – Department of Surgery, University of British Columbia; Brian Bressler, M.D. – Department of Medicine, University of British Columbia; Murali Dhar, PhD – Bristol-Myers Squibb; Qihong Zhao, M.D., Ph.D. – Bristol-Myers Squibb; Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia
Dominic A. Boardman, PhD – Department of Surgery, University of British Columbia ### 738374###Presenting Author @@@ Rosa V. Garcia – Department of Surgery, University of British Columbia ### 520281###Co-Author @@@ Sabine Ivison, PhD – Department of Surgery, University of British Columbia ### 738375###Co-Author @@@ Brian Bressler, M.D. – Department of Medicine, University of British Columbia ### 520283###Co-Author @@@ Murali Dhar, PhD – Bristol-Myers Squibb ### 738376###Co-Author @@@ Qihong Zhao, M.D., Ph.D. – Bristol-Myers Squibb ### 738377###Co-Author @@@ Megan K. Levings, Ph.D. – Department of Surgery, University of British Columbia ### 308419###Co-Author
Neutrophil maturation and their response to infectious pathogens are regulated by microbiota Location: Salon A-D, 4th Floor Anastasia Petenkova, PhD – Brigham and Women's Hospital; Abirami Kugadas, PhD – Brigham and Women's Hospital; Jennifer Geddes-McAlister, PhD – University of Guelph; Michael Mansour, MD, PhD – Massachusetts General Hospital; David Sykes, MD, PhD – Massachusetts General Hospital; Mihaela Gadjeva, PhD – Brigham and Women's Hospital
Soumya Raychaudhuri, MD, PhD – Brigham and Women's Hospital/Harvard Medical School ### 738272###Speaker
2:05 PM - 2:20 PM
Human tolerogenic dendritic cells used in a phase I/II clinical trial regulate immune responses through lactate synthesis Location: Salon A-D, 4th Floor Eros Marin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Laurence Bouchet-Delbos – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Véronique Nerrière-Daguin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Gilles Blancho, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes; Claire Pecqueur – Centre de Recherche en Cancérologie et Immunologie Nantes-Angers, UMR1232 INSERM, Université de Nantes; Maria-Cristina Cuturi – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes; Aurelie Moreau – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes
Eros Marin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes ### 738352###Co-Author @@@ Laurence Bouchet-Delbos – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes ### 738353###Co-Author @@@ Véronique Nerrière-Daguin – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes ### 738354###Co-Author @@@ Gilles Blancho, MD – Centre de Recherche en Transplantation et Immunologie (CRTI) UMR 1064, INSERM, Université de Nantes, ITUN, CHU de Nantes ### 738355###Co-Author @@@ Claire Pecqueur – Centre de Recherche en Cancérologie et Immunologie Nantes-Angers, UMR1232 INSERM, Université de Nantes ### 738356###Co-Author @@@ Maria-Cristina Cuturi – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes ### 738357###Co-Author @@@ Aurelie Moreau – Centre de Recherche en Transplantation et Immunologie / Institut de Transplantation Nephrologie Urologie, UMR1064 INSERM, Université de Nantes, CHU Nantes ### 738358###Presenting Author
Megan A. Cooper, MD, PhD – Washington University ### 651470###Speaker
1:25 PM - 1:40 PM
Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β Location: Salon H-K, 4th Floor Juan Li – The Rockefeller University; Marco Ritelli – University of Brescia; Cindy Ma – Garvan Institute of Medical Research; Geetha Rao – Garvan Institute of Medical Research; Emilie Corvilain – INSERM U1163; Sophie Cypowyj – The Rockefeller University; Lucie Grodecká – Centre for Cardiovascular Surgery and Transplantation; Romain Lévy – INSERM U1163; Vivien Béziat – INSERM U1163; Lei Shang – The Rockefeller University; Kathryn Payne – Garvan Institute of Medical Research; Danielle Avery – Garvan Institute of Medical Research; Mélanie Migaud – INSERM U1163; Soraya Boucherit – INSERM U1163; Sabri Boughorbel – Sidra Medicine; Salim Bougarn – Sidra Medicine; Andrea Guennoun – Sidra Medicine; Maya Chrabieh – INSERM U1163; Franck Rapaport – The Rockefeller University; Benedetta Bigio – The Rockefeller University; Yuval Itan – The Rockefeller University; Bertrand Boisson – The Rockefeller University; Valérie Cormier-Daire – Imagine Institute; Delfien Syx – Ghent University Hospital; Fransiska Malfait – Ghent University Hospital; Nicoletta Zoppi – University of Brescia; Laurent Abel – INSERM U1163; Tomáš Freiberger – Centre for Cardiovascular Surgery and Transplantation; Nico Marr – Sidra Medicine; Stuart Tangye, PhD – Garvan Institute of Medical Research; Marina Colombi – University of Brescia; Anne Puel – INSERM U1163; Jean-Laurent Casanova – The Rockefeller University
Juan Li – The Rockefeller University ### 738441###Presenting Author @@@ Marco Ritelli – University of Brescia ### 738442###Co-Author @@@ Cindy Ma – Garvan Institute of Medical Research ### 738443###Co-Author @@@ Geetha Rao – Garvan Institute of Medical Research ### 738444###Co-Author @@@ Emilie Corvilain – INSERM U1163 ### 738445###Co-Author @@@ Sophie Cypowyj – The Rockefeller University ### 738446###Co-Author @@@ Lucie Grodecká – Centre for Cardiovascular Surgery and Transplantation ### 738447###Co-Author @@@ Romain Lévy – INSERM U1163 ### 738448###Co-Author @@@ Vivien Béziat – INSERM U1163 ### 738449###Co-Author @@@ Lei Shang – The Rockefeller University ### 738450###Co-Author @@@ Kathryn Payne – Garvan Institute of Medical Research ### 738451###Co-Author @@@ Danielle Avery – Garvan Institute of Medical Research ### 738452###Co-Author @@@ Mélanie Migaud – INSERM U1163 ### 738453###Co-Author @@@ Soraya Boucherit – INSERM U1163 ### 738454###Co-Author @@@ Sabri Boughorbel – Sidra Medicine ### 366501###Co-Author @@@ Salim Bougarn – Sidra Medicine ### 738455###Co-Author @@@ Andrea Guennoun – Sidra Medicine ### 738456###Co-Author @@@ Maya Chrabieh – INSERM U1163 ### 738457###Co-Author @@@ Franck Rapaport – The Rockefeller University ### 738458###Co-Author @@@ Benedetta Bigio – The Rockefeller University ### 738459###Co-Author @@@ Yuval Itan – The Rockefeller University ### 738460###Co-Author @@@ Bertrand Boisson – The Rockefeller University ### 738461###Co-Author @@@ Valérie Cormier-Daire – Imagine Institute ### 738462###Co-Author @@@ Delfien Syx – Ghent University Hospital ### 738463###Co-Author @@@ Fransiska Malfait – Ghent University Hospital ### 738464###Co-Author @@@ Nicoletta Zoppi – University of Brescia ### 738465###Co-Author @@@ Laurent Abel – INSERM U1163 ### 738466###Co-Author @@@ Tomáš Freiberger – Centre for Cardiovascular Surgery and Transplantation ### 738467###Co-Author @@@ Nico Marr – Sidra Medicine ### 738468###Co-Author @@@ Stuart Tangye, PhD – Garvan Institute of Medical Research ### 365531###Co-Author @@@ Marina Colombi – University of Brescia ### 738469###Co-Author @@@ Anne Puel – INSERM U1163 ### 738470###Co-Author @@@ Jean-Laurent Casanova – The Rockefeller University ### 738471###Co-Author
Scott Snapper, MD, PhD – Children's Hospital Boston ### 651487###Speaker
2:05 PM - 2:20 PM
Loss of IL6R Causes Immunodeficiency, Atopy, and Abnormal Inflammatory Responses Location: Salon H-K, 4th Floor Sarah Spencer, MBChB MSc MRCP – Department of Medicine, University of Cambridge; William Egner, PhD – Sheffield Teaching Hospitals NHS Foundation Trust; Sevgi Kostel Bal, MD – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Hana Lango Allen, PhD – Department of Haematology, University of Cambridge; Irfan Raza Syed, PhD – Quaid-i-Azam University; Chi Adrian Ma, PhD – National Institute of Allergy and Infectious Diseases; Meltem Gurel, BSc – Cancer Research UK Cambridge Institute; Yuan Zhang, PhD – National Institute of Allergy and Infectious Diseases; Guanping Sun, PhD – National Institute of Allergy and Infectious Diseases; Ruth A Sabroe, MD – Department of Dermatology, Sheffield Teaching Hospitals NHS Trust; Daniel Greene, PhD – Department of Haematology, University of Cambridge; William Rae, MSc – Department of Medicine, University of Cambridge; Tala Shahin, MRes – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Katarzyna Kania, PhD – Cancer Research UK Cambridge Institute; Rico Chandra Ardy, MRes – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Annika Pecchia-Bekkum, MSc – Department of Medicine, University of Cambridge; William P.M. Worrall, BSc – Department of Medicine, University of Cambridge; Jonathan Stephens, PhD – Department of Haematology, University of Cambridge; Matthew Brown, BSc – Department of Haematology, University of Cambridge; Salih Tuna, PhD – Department of Haematology, University of Cambridge; Melanie York, MSc – Sheffield Teaching Hospitals NHS Foundation Trust; Fiona Shackley, MBChB – Sheffield Teaching Hospitals NHS Foundation Trust; Diarmuid Kerrin, BM – Barnsley Hospitals NHS Foundation Trust; Ravishakar Sargur, MD – Sheffield Teaching Hospitals NHS Foundation Trust; Alison Condliffe, PhD – Sheffield Teaching Hospitals NHS Foundation Trust; Hamid Nawaz Tipu, MBBS – Immunology Department, Armed Forces Institute of Pathology; Ernest Turro, PhD – Department of Haematology, University of Cambridge; Simon Tavare, PhD – Herbert and Florence Irving Institute for Cancer Dynamics; Adrian Thrasher, PhD – Molecular and Cellular Immunology Section, UCL Great Ormond Street Institute of Child Health; Duncan Jodrell, PhD – Cancer Research UK Cambridge Institute; Kenneth G.C. Smith, PhD – Department of Medicine, University of Cambridge; Kaan Boztug, PhD – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases; Joshua D. Milner, PhD – National Institute of Allergy and Infectious Diseases; James E.D. Thaventhiran, PhD – Cancer Research UK Cambridge Institute
Sarah Spencer, MBChB MSc MRCP – Department of Medicine, University of Cambridge ### 738318###Presenting Author @@@ William Egner, PhD – Sheffield Teaching Hospitals NHS Foundation Trust ### 738319###Co-Author @@@ Sevgi Kostel Bal, MD – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases ### 738320###Co-Author @@@ Hana Lango Allen, PhD – Department of Haematology, University of Cambridge ### 738321###Co-Author @@@ Irfan Raza Syed, PhD – Quaid-i-Azam University ### 738322###Co-Author @@@ Chi Adrian Ma, PhD – National Institute of Allergy and Infectious Diseases ### 738323###Co-Author @@@ Meltem Gurel, BSc – Cancer Research UK Cambridge Institute ### 738324###Co-Author @@@ Yuan Zhang, PhD – National Institute of Allergy and Infectious Diseases ### 738325###Co-Author @@@ Guanping Sun, PhD – National Institute of Allergy and Infectious Diseases ### 738326###Co-Author @@@ Ruth A Sabroe, MD – Department of Dermatology, Sheffield Teaching Hospitals NHS Trust ### 738327###Co-Author @@@ Daniel Greene, PhD – Department of Haematology, University of Cambridge ### 738328###Co-Author @@@ William Rae, MSc – Department of Medicine, University of Cambridge ### 738329###Co-Author @@@ Tala Shahin, MRes – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases ### 738330###Co-Author @@@ Katarzyna Kania, PhD – Cancer Research UK Cambridge Institute ### 738331###Co-Author @@@ Rico Chandra Ardy, MRes – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases ### 738332###Co-Author @@@ Annika Pecchia-Bekkum, MSc – Department of Medicine, University of Cambridge ### 738333###Co-Author @@@ William P.M. Worrall, BSc – Department of Medicine, University of Cambridge ### 738334###Co-Author @@@ Jonathan Stephens, PhD – Department of Haematology, University of Cambridge ### 738335###Co-Author @@@ Matthew Brown, BSc – Department of Haematology, University of Cambridge ### 738336###Co-Author @@@ Salih Tuna, PhD – Department of Haematology, University of Cambridge ### 738337###Co-Author @@@ Melanie York, MSc – Sheffield Teaching Hospitals NHS Foundation Trust ### 738338###Co-Author @@@ Fiona Shackley, MBChB – Sheffield Teaching Hospitals NHS Foundation Trust ### 738339###Co-Author @@@ Diarmuid Kerrin, BM – Barnsley Hospitals NHS Foundation Trust ### 738340###Co-Author @@@ Ravishakar Sargur, MD – Sheffield Teaching Hospitals NHS Foundation Trust ### 738341###Co-Author @@@ Alison Condliffe, PhD – Sheffield Teaching Hospitals NHS Foundation Trust ### 738342###Co-Author @@@ Hamid Nawaz Tipu, MBBS – Immunology Department, Armed Forces Institute of Pathology ### 738343###Co-Author @@@ Ernest Turro, PhD – Department of Haematology, University of Cambridge ### 738344###Co-Author @@@ Simon Tavare, PhD – Herbert and Florence Irving Institute for Cancer Dynamics ### 738345###Co-Author @@@ Adrian Thrasher, PhD – Molecular and Cellular Immunology Section, UCL Great Ormond Street Institute of Child Health ### 738346###Co-Author @@@ Duncan Jodrell, PhD – Cancer Research UK Cambridge Institute ### 738347###Co-Author @@@ Kenneth G.C. Smith, PhD – Department of Medicine, University of Cambridge ### 738348###Co-Author @@@ Kaan Boztug, PhD – Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases ### 738349###Co-Author @@@ Joshua D. Milner, PhD – National Institute of Allergy and Infectious Diseases ### 738350###Co-Author @@@ James E.D. Thaventhiran, PhD – Cancer Research UK Cambridge Institute ### 738351###Co-Author
