Autoimmunity is on the rise around the globe. An estimated 70% of autoimmune disease cases are due to environmental factors. Diet has been proposed as a risk factor for autoimmunity and shown to modulate the severity of several autoimmune disorders. Yet, the interactions between diet and autoimmunity in humans remains largely unstudied. Here, we systematically interrogated commonly consumed animals and plants for peptide epitopes previously implicated in seventy seven human autoimmune diseases. A total of fourteen species could be divided into three broad categories regarding their content in human autoimmune epitopes. Strikingly, however, pig contains a disproportionately high number of autoimmune epitopes not found in any of the other species analyzed. Importantly, these epitopes were found to be expressed across all tissues collectively. Ongoing analyses focus on mapping autoimmune epitopes present in food onto specific HLA alleles and inspecting epidemiological data on diet and autoimmune disease incidence. This work sheds light on potential new links between diet and autoimmunity in humans and lays the foundation for future mechanistic studies on the impact of diet on the pathogenesis and progression of autoimmune disorders.