Oral Abstract

184 - Late Breaker Oral Abstract Session 2

Presentations:

• 1:45 PM - 1:55 PM

  LB8 - Microarray Patch Delivery of Long-Acting HIV PrEP and Contraception
  Annie Rein-Weston, MPH – PATH; Ismaiel Tekko, PhD – Queen's University Belfast; Lalit Vora, MPharm, PhD – Queen's University Belfast; Courtney Jarrahian, MS – PATH; Bill Spreen, PharmD – ViiV Healthcare; Trevor Scott, RPh, PhD – ViiV Healthcare; Ryan Donnelly, PhD – Queen's University Belfast; Darin Zehrung, MBA – PATH
• 1:55 PM - 2:05 PM

  LB9 - The Effect of Initiating Integrase Inhibitor-based vs. Non-Nucleoside Reverse Transcriptase Inhibitor-based Antiretroviral Therapy on Progression to Diabetes among North American Persons in HIV Care
  Peter F. Rebeiro, PhD, MHS – Vanderbilt University Medical Center; Cathy Jenkins, MS – Vanderbilt University Medical Center; Aihua Bian, MS – Vanderbilt University Medical Center; Jordan Lake, MD – University of Texas Health Science Center at Houston; Kassem Bourgi, MD – Indiana University School of Medicine; Michael A. Horberg, MD, MAS – Kaiser Permanente Mid-Atlantic States; Richard Moore, MD – Johns Hopkins University; Keri Altoff, PhD, MPH – Johns Hopkins University; Marina Klein, MD, MSc – McGill University Health Centre; Joseph J. Eron, Jr., MD – University of North Carolina; M. John Gill, MB, ChB, MSc – University of Calgary; Mari Kitahata, MD, MPH – University of Washington; Sonia Napravnik, PhD, MPH – University of North Carolina at Chapel Hill; Michael Silverberg, PhD, MPH – Kaiser Permanente Northern California; Angel M. Mayor, MD – Universidad Central del Caribe; Amanda Willig, PhD, RD – University of Alabama at Birmingham; Michelle Floris-Moore, MD – University of North Carolina at Chapel Hill; Timothy Sterling, MD – Vanderbilt University Medical Center; John R. Koethe, MD – Vanderbilt University Medical Center
• 2:05 PM - 2:15 PM

  LB10 - A Randomized, Double-Blind, Placebo-Controlled Efficacy Trial of a Vaccine to Prevent Chronic Hepatitis C Virus Infection in an at-Risk Population
  Andrea L. Cox, MD;PHD – Johns Hopkins University; Kimberly Page, PhD – Univ. of New Mexico; Michael Melia, MD – Johns Hopkins University; Rebecca Veenhuis, PhD – Johns Hopkins University; Guido Massaccesi, BS – Johns Hopkins University; William Osburn, PhD – Johns Hopkins University; Katherine Wagner, MPH – The University of New Mexico; Linda Giudice, MD,PhD – The University of California, San Francisco; Ellen Stein, MPH – The University of California, San Francisco; Alice K. Asher, PhD – The University of California, San Francisco; Ventzislav Vassilev, PhD – GlaxoSmithKline Vaccines; Lan Lin, MD – GlaxoSmithKline Vaccines; Alfredo Nicosia, PhD – 5ReiThera, srl; Stefania Capone, BS – 5ReiThera, srl; Elisa Scarselli, PhD – 5ReiThera, srl; Antonella Folgori, PhD – 5ReiThera, srl; Richard Gorman, MD – The National Institute of Allergy and Infectious Diseases; Soju Chang, MD – The National Institute of Allergy and Infectious Diseases; Peter Wolff, MHA – The National Institute of Allergy and Infectious Diseases; T. Jake Liang, MD – The National Institute of Diabetes and Digestive and Kidney Diseases; Marc Ghany, MD – The National Institute of Diabetes and Digestive and Kidney Diseases; Michael Wierzbicki, PhD – The Emmes Company; Paula Lum, MD, MPH – The University of California, San Francisco
• 2:15 PM - 2:25 PM

  LB11 - A Single Dose of the MVA-BN Smallpox Vaccine Induces an Early Protective Antibody Response Similar to a Traditional Replicating Vaccine and is Suitable for Emergency Scenarios
  Jane Maclennan, BSc MRPharmS – Bavarian Nordic; Heinz Weidenthaler, MD – Bavarian Nordic; Phillip Pittman, MD – USAMRIID; Darja Schmidt, PhD – Bavarian Nordic; Paul Chaplin, PhD – Bavarian Nordic
• 2:25 PM - 2:35 PM

  LB12 - A Randomized Controlled Trial of Antibody Response to 2018-19 Cell-based vs. Egg-based Quadrivalent Inactivated Influenza Vaccine in Children
  Krissy Moehling, PhD – University of Pittsburgh; Chyongchiou Lin, PhD – Universityof Pittsburgh; Judith Martin, MD – University of Pittsburgh; John F. Alcorn, PhD – University of Pittsburgh; Michael Susick, MPH – Universtiy of Pittsburgh; Patricia Nowalk, PhD – University of Pittsburgh; Min Levine, PhD – Centers for Diease Control and Prevention; Brendan Flannery, PhD – Centers for Disease Control and Prevention; Richard K. Zimmerman, MA;MD;MPH;MS – University of Pittsburgh
• 2:35 PM - 2:45 PM

  LB13 - Trivalent hepatitis B (HepB) vaccine yields superior seroprotection rates in adults: results from the phase 3 double-blind, randomized study comparing immunogenicity and safety of a 3-dose regimen of Sci-B-Vac™ and Engerix B®(PROTECT)
  Joanne M. Langley, MD – Dalhousie University; Timo Vesikari, MD – Vaccine Research Center; Bruce Smith, PhD – Dalhousie University; Pierre van Damme, MD, PhD – University of Antwerp, Campus Drie Eiken; Isabel Leroux-Roels, MD PhD – Ghent University & Ghent University Hospital; Geert Leroux-Roels, MD – Ghent University Hospital; Johanna Spaans, BSc, MSc – VBI Vaccines Inc.; Nathalie Machluf, PhD – SciVac Ltd; Bebi Yassin-Rajkumar, n/a – Sponsor; Dave Anderson, PhD – VBI Vaccines; Vlad Popovic, MD – VBI Vaccines; Francisco Diaz-Mitoma, MD – VBI Vaccines
• 2:45 PM - 2:55 PM

  LB14 - Cerebrospinal fluid profiling of the human host response reveals species-specific enterovirus biosignatures in acute flaccid myelitis cases
  Benjamin J. Briggs, MD, PHD – UCSF; Yale Santos, BS – UCSF; Akshaya Ramesh, PhD – UCSF; Manfred Grabherr, PhD – Uppsala University; Asmeeta Achari, MS, BS – UCSF; Guixia Yu, BS – UCSF; Steve Miller, MD, PhD – Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA; Scot Federman, BA – UCSF; Shaun Arevalo, BS – UCSF; Hannah Sample, BS – UCSF; Kelsey Zorn, MHS, BA – UCSF; Kathleen Harriman, PhD, MPH, RN, – California Department of Public Health; Sharon Messenger, PhD – California Department of Public Health; Samuel Dominguez, MD, PhD – University of Colorado, School of Medicine; Carol Glaser, MD, DVM – Kaiser Permanente; Debra Wadford, PhD – California Department of Public Health; Kevin Messacar, MD – University of Colorado; Michael Wilson, MD – UCSF; Charles Chiu, MD, PhD – UCSF

Co-Author(s)

• JM

  Jane Maclennan, BSc MRPharmS

  Clinical Program Lead
  Bavarian Nordic
  Martinsried, Bayern, Germany

  Disclosure: Bavarian Nordic: Employee
  Bavarian Nordic: Employee, Shareholder
• KM

  Krissy Moehling, PhD

  Post Doctoral Fellow
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• CJ

  Cathy Jenkins, MS

  Biostatistician
  Vanderbilt University Medical Center
  Nashville, TN

  Disclosure: Nothing to disclose
• CL

  Chyongchiou Lin, PhD

  Associate Professor
  Universityof Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• KP

  Kimberly Page, PhD

  Professor
  Univ. of New Mexico
  Albuquerque, NM

  Disclosure: Nothing to disclose
• YS

  Yale Santos, BS

  Bioinformatician
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• IT

  Ismaiel Tekko, PhD

  Research Fellow
  Queen's University Belfast
  Belfast, Northern Ireland, United Kingdom

  Disclosure: Nothing to disclose
• TV

  Timo Vesikari, MD

  Professor
  Vaccine Research Center
  Tampere, Pirkanmaa, Finland
• HW

  Heinz Weidenthaler, MD

  Vice President, Clinical Strategy Infectious Diseases
  Bavarian Nordic
  Martinsried, Bayern, Germany

  Disclosure: Bavarian Nordic: Employee, Shareholder
• AB

  Aihua Bian, MS

  Biostatistician
  Vanderbilt University Medical Center
  Nashville, TN

  Disclosure: Nothing to disclose
• JM

  Judith Martin, MD

  Professor
  University of Pittsburgh
  Pittsburgh, Pennsylvania

  Disclosure: Nothing to disclose
• 

  Michael Melia, MD

  Assoc. Professor
  Johns Hopkins University
  Baltimore, Maryland

  Disclosure: Gilead Sciences, Inc.: Research Grant
• AR

  Akshaya Ramesh, PhD

  Postdoctoral Scholar
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• BS

  Bruce Smith, PhD

  Professor
  Dalhousie University
  Halifax, NS, Canada

  Disclosure: Nothing to disclose
• LV

  Lalit Vora, MPharm, PhD

  Research Fellow
  Queen's University Belfast
  Belfast, Northern Ireland, United Kingdom

  Disclosure: Nothing to disclose
• JA

  John Alcorn, PhD

  Associate Professor
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• MG

  Manfred Grabherr, PhD

  Faculty of Medicine
  Uppsala University
  Uppsala, Uppsala Lan, Sweden

  Disclosure: Nothing to disclose
• CJ

  Courtney Jarrahian, MS

  Program Advisor, Medical Devices and Health Technologies
  PATH
  Seattle, WA

  Disclosure: Nothing to disclose
• JL

  Jordan Lake, MD

  Associate Professor
  University of Texas Health Science Center at Houston
  Houston, TX

  Disclosure: Nothing to disclose
• DS

  Darja Schmidt, PhD

  Senior Manager
  Bavarian Nordic
  Martinsried, Bayern, Germany

  Disclosure: Bavarian Nordic: Employee, Shareholder
• Pv

  Pierre van Damme, MD, PhD

  professor
  University of Antwerp, Campus Drie Eiken
  wilrijk, Antwerpen, Belgium

  Disclosure: Nothing to disclose
• RV

  Rebecca Veenhuis, PhD

  Research Assitant
  Johns Hopkins University
  Baltimore, MD

  Disclosure: Nothing to disclose
• AA

  Asmeeta Achari, MS, BS

  Technician
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• KB

  Kassem Bourgi, MD

  Assistant Professor
  Indiana University School of Medicine
  Indianapolis, IN

  Disclosure: Gilead Sciences: Grant/Research Support
• PC

  Paul Chaplin, PhD

  President and CEO
  Bavarian Nordic
  Kvistgard, Hovedstaden, Denmark

  Disclosure: Bavarian Nordic: Board Member, Employee, Shareholder
  Bavarian Nordic: Employee, Shareholder
• IL

  Isabel Leroux-Roels, MD PhD

  Principal Investigator
  Ghent University & Ghent University Hospital
  Ghent, Oost-Vlaanderen, Belgium

  Disclosure: Nothing to disclose
• GM

  Guido Massaccesi, BS

  Technician
  Johns Hopkins University
  Baltimore, MD

  Disclosure: Nothing to disclose
• BS

  Bill Spreen, PharmD

  Vice President, Medicine Development Leader - Cabotegravir
  ViiV Healthcare
  Research Triangle Park, NC

  Disclosure: ViiV Healthcare: Employee
• MS

  Michael Susick, MPH

  Research Assistant
  Universtiy of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• MH

  Michael Horberg, MD, MAS

  Associate Medical Director Research, Medical Education
  Kaiser Permanente Mid-Atlantic States
  Rockville, Maryland

  Disclosure: Nothing to disclose
• GL

  Geert Leroux-Roels, MD

  Dr.
  Ghent University Hospital
  Ghent, Oost-Vlaanderen, Belgium

  Disclosure: Nothing to disclose
• PN

  Patricia Nowalk, PhD

  Professor
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: MERCK & CO: Grant/Research Support
• WO

  William Osburn, PhD

  Assistant Professor
  Johns Hopkins University
  Baltimore, MD

  Disclosure: Nothing to disclose
• TS

  Trevor Scott, RPh, PhD

  Vice President and Head of Business Development and Alliance Management
  ViiV Healthcare
  Research Triangle Park, NC

  Disclosure: ViiV Healthcare: Employee
• GY

  Guixia Yu, BS

  Technician
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• RD

  Ryan Donnelly, PhD

  Chair in Pharmaceutical Technology
  Queen's University Belfast
  Belfast, Northern Ireland, United Kingdom

  Disclosure: Nothing to disclose
• ML

  Min Levine, PhD

  Pandemic Preparedness Team Lead
  Centers for Diease Control and Prevention
  Atlanta, GA

  Disclosure: Nothing to disclose
• SM

  Steve Miller, MD, PhD

  Professor and Director
  Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA
  San Francisco, CA

  Disclosure: Nothing to disclose
• RM

  Richard Moore, MD

  Professor
  Johns Hopkins University
  Baltimore, MD

  Disclosure: Nothing to disclose
• JS

  Johanna Spaans, BSc, MSc

  Ms
  VBI Vaccines Inc.
  Ottawa, ON, Canada

  Disclosure: VBI Vaccines: Employee
• KW

  Katherine Wagner, MPH

  Reserach Assistant
  The University of New Mexico
  Albuquerque, NM

  Disclosure: Nothing to disclose
• KA

  Keri Altoff, PhD, MPH

  Associate Professor
  Johns Hopkins University
  Baltimore, Maryland

  Disclosure: Nothing to disclose
• SF

  Scot Federman, BA

  Bioinformatician
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• BF

  Brendan Flannery, PhD

  US Flu VE Network PI at CDC
  Centers for Disease Control and Prevention
  Atlanta, GA

  Disclosure: Nothing to disclose
• LG

  Linda Giudice, MD,PhD

  Professor
  The University of California, San Francisco
  San Francicso, CA

  Disclosure: Nothing to disclose
• NM

  Nathalie Machluf, PhD

  Senior Director Regulatory Affairs
  SciVac Ltd
  Rehovot, HaMerkaz, Israel

  Disclosure: SciVac Ltd: Employee
• DZ

  Darin Zehrung, MBA

  Global Program Leader, Medical Devices and Health Technologies
  PATH
  Seattle, WA

  Disclosure: Nothing to disclose
• SA

  Shaun Arevalo, BS

  Clinical Laboratory Technician
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• MK

  Marina Klein, MD, MSc

  Professor
  McGill University Health Centre
  Montreal, QC, Canada

  Disclosure: Nothing to disclose
• ES

  Ellen Stein, MPH

  Reserach Coordinator
  The University of California, San Francisco
  San Francisco, CA

  Disclosure: Nothing to disclose
• BY

  Bebi Yassin-Rajkumar, n/a

  Senior Clinical Programs Manager
  Sponsor
  Ottawa, ON, Canada

  Disclosure: Nothing to disclose
• DA

  Dave Anderson, PhD

  Dr.
  VBI Vaccines
  Cambridge, MA

  Disclosure: VBI Vaccines, Inc.: Employee, Shareholder
• AA

  Alice Asher, PhD

  Research Coordinator
  The University of California, San Francisco
  San Francisco, CA

  Disclosure: Nothing to disclose
• 

  Joseph Eron, Jr., MD

  Professor of Medicine
  University of North Carolina
  Chapel Hill, NC

  Disclosure: Gilead Sciences: Consultant, Research Grant, The research grants/contract are to the University of North Carolina on which i am an investigator.
  Janssen: Consultant, Research Grant, The research grants/contract are to the University of North Carolina on which i am an investigator.
  Merck and Co.: Consultant
  ViiV HealthCare Inc: Consultant, Research Grant, The research grants/contract are to the University of North Carolina on which i am an investigator.
• HS

  Hannah Sample, BS

  Project Manager
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• MG

  M. John Gill, MB, ChB, MSc

  Professor
  University of Calgary
  Calgary, AB, Canada

  Disclosure: Gilead: Board Member
  Merck: Board Member
  Viiv: Board Member
• VP

  Vlad Popovic, MD

  VP, Clinical Development & Medical Affairs
  VBI Vaccines
  mississauga, ON, Canada

  Disclosure: VBI Vaccines: Employee
• VV

  Ventzislav Vassilev, PhD

  Director
  GlaxoSmithKline Vaccines
  Wavre, Brussels Hoofdstedelijk Gewest, Belgium

  Disclosure: GlaxoSmithKlein Vaccines: Employee
• KZ

  Kelsey Zorn, MHS, BA

  Clinical Research Coordinator
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• FD

  Francisco Diaz-Mitoma, MD

  Dr.
  VBI Vaccines
  Ottawa, ON, Canada

  Disclosure: VBI Vaccines, Inc.: Consultant, Shareholder, Independent Contractor
• KH

  Kathleen Harriman, PhD, MPH, RN,

  Section Chief
  California Department of Public Health
  San Francisco, CA

  Disclosure: Nothing to disclose
• MK

  Mari Kitahata, MD, MPH

  Professor
  University of Washington
  Seattle, WA

  Disclosure: Nothing to disclose
• LL

  Lan Lin, MD

  Medical Director
  GlaxoSmithKline Vaccines
  Wavre, Brussels Hoofdstedelijk Gewest, Belgium

  Disclosure: GlaxoSmithKlein Vaccines: Employee
• SM

  Sharon Messenger, PhD

  Division Supervisor
  California Department of Public Health
  Richmond, CA

  Disclosure: Nothing to disclose
• SN

  Sonia Napravnik, PhD, MPH

  Associate Professor
  University of North Carolina at Chapel Hill
  Chapel Hill, NC

  Disclosure: Nothing to disclose
• AN

  Alfredo Nicosia, PhD

  Director
  5ReiThera, srl
  Rome, Piemonte, Italy

  Disclosure: ReiThera: Employee, Shareholder
• SC

  Stefania Capone, BS

  Scientist
  5ReiThera, srl
  Rome, Piemonte, Italy

  Disclosure: Nothing to disclose
• SD

  Samuel Dominguez, MD, PhD

  Associate Professor
  University of Colorado, School of Medicine
  San Francisco, California

  Disclosure: Nothing to disclose
• MS

  Michael Silverberg, PhD, MPH

  Research Scientist
  Kaiser Permanente Northern California
  Oakland, CA

  Disclosure: Gilead: Grant/Research Support
• CG

  Carol Glaser, MD, DVM

  Physician
  Kaiser Permanente
  Oakland, CA

  Disclosure: Nothing to disclose
• AM

  Angel Mayor, MD

  Associate Professor
  Universidad Central del Caribe
  Carolina, Puerto Rico

  Disclosure: Nothing to disclose
• ES

  Elisa Scarselli, PhD

  Scientist
  5ReiThera, srl
  Rome, Piemonte, Italy

  Disclosure: Nothing to disclose
• AF

  Antonella Folgori, PhD

  Scientist
  5ReiThera, srl
  Rome, Piemonte, Italy

  Disclosure: ReiThera: Employee
  ReiThera: Employee, Shareholder
• DW

  Debra Wadford, PhD

  Laboratory Director
  California Department of Public Health
  Richmond, CA

  Disclosure: Nothing to disclose
• AW

  Amanda Willig, PhD, RD

  Assistant Professor
  University of Alabama at Birmingham
  Birmingham, AL

  Disclosure: Nothing to disclose
• 

  Michelle Floris-Moore, MD

  Associate Professor
  University of North Carolina at Chapel Hill
  Chapel Hill, North Carolina

  Disclosure: Nothing to disclose
• RG

  Richard Gorman, MD

  Medical monitor
  The National Institute of Allergy and Infectious Diseases
  Rockville, MD

  Disclosure: Nothing to disclose
• 

  Kevin Messacar, MD

  Assistant Professor
  University of Colorado
  Denver, Colorado

  Disclosure: Nothing to disclose
• SC

  Soju Chang, MD

  Medical monitor
  The National Institute of Allergy and Infectious Diseases
  Rockville, MD

  Disclosure: Nothing to disclose
• TS

  Timothy Sterling, MD

  Professor
  Vanderbilt University Medical Center
  Nashville, TN

  Disclosure: Nothing to disclose
• MW

  Michael Wilson, MD

  Associate Professor
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• CC

  Charles Chiu, MD, PhD

  Professor
  UCSF
  San Francisco, California

  Disclosure: Nothing to disclose
• JK

  John Koethe, MD

  Associate Professor
  Vanderbilt University Medical Center
  Nashville, TN

  Disclosure: Nothing to disclose
• PW

  Peter Wolff, MHA

  Trial Coordinator
  The National Institute of Allergy and Infectious Diseases
  Rockville, MD

  Disclosure: Nothing to disclose
• TL

  T. Jake Liang, MD

  Scientist
  The National Institute of Diabetes and Digestive and Kidney Diseases
  Bethesda, MD

  Disclosure: Nothing to disclose
• MG

  Marc Ghany, MD

  Scientist
  The National Institute of Diabetes and Digestive and Kidney Diseases
  Bethesda, MD

  Disclosure: Nothing to disclose
• MW

  Michael Wierzbicki, PhD

  Statistician
  The Emmes Company
  Rockville, MD

  Disclosure: Nothing to disclose
• PL

  Paula Lum, MD, MPH

  Associate Professor
  The University of California, San Francisco
  San Francisco, CA

  Disclosure: Nothing to disclose

Moderator(s)

• 

  Michelle Floris-Moore, MD

  Associate Professor
  University of North Carolina at Chapel Hill
  Chapel Hill, North Carolina

  Disclosure: Nothing to disclose
• 

  Kevin Messacar, MD

  Assistant Professor
  University of Colorado
  Denver, Colorado

  Disclosure: Nothing to disclose

Presenting Author(s)

• BB

  Benjamin Briggs, MD, PHD

  Junior Faculty
  UCSF
  San Francisco, CA

  Disclosure: Nothing to disclose
• AC

  Andrea Cox, MD;PHD

  Professor of Medicine and Oncology
  Johns Hopkins University
  Baltimore, MD

  Disclosure: Nothing to disclose
• JL

  Joanne Langley, MD

  Professor of Pediatrics and Community Health and Epidemiology
  Dalhousie University
  Halifax, NS, Canada
• PR

  Peter Rebeiro, PhD, MHS

  Assistant Professor
  Vanderbilt University Medical Center
  Nashville, TN

  Disclosure: Nothing to disclose
• AR

  Annie Rein-Weston, MPH

  Technical Officer
  PATH
  Seattle, WA

  Disclosure: Nothing to disclose
• PP

  Phillip Pittman, MD

  Director, Department of Clinical Research
  USAMRIID
  Fort Detrick, MD

  Disclosure: Bavarian Nordic: Scientific Research Study Investigator
• RZ

  Richard Zimmerman, MA;MD;MPH;MS

  Dr
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose