Stroke

Clinical Practice (assessment, diagnosis, treatment, knowledge translation/EBP, implementation science, program development)

Measurement

Special Symposium

SPECIAL SYMPOSIUM & ASA/ACRM Award for Excellence in Post-Acute Stroke Rehabilitation: Biomarkers in Stroke Recovery and Rehabilitation Research (599776)

Presenter(s)

• 

  Steven Cramer, MD

  Professor, Department of Neurology
  University of California, Los Angeles
  Los Angeles, California

Moderator(s)

• 

  Pamela Roberts, PhD, OTR/L, SCFES, FAOTA, CPHQ, FNAP, FACRM

  Executive Director and Professor
  Cedars-Sinai
  Valley Village, California

A number of therapies are emerging that aim to promote favorable brain plasticity after stroke, with the goal being to improve outcomes and reduce disability. Treating the brain is not a “one-size-fits-all” process. Instead, certain treatments are more, or less, likely to improve brain function in specific subsets of patients. This presentation will briefly review the range of therapies under study, then focus on measurements that have been evaluated for predicting responders versus non-responders in the context of restorative therapies after stroke, with an emphasis on studies targeting the motor system.

Learning Objectives:

• learn at least 3 classes of restorative therapy under study in human patients with stroke
• identify at least 3 classes of measurement used to predict treatment response in this context
• distinguish measures that are obtained at baseline to predict treatment response from measures obtained serially during therapy to capture effects of an intervention.