Category: Brain Injury; Clinical Practice (assessment, diagnosis, treatment, knowledge translation/EBP, implementation science, program development)
Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) are associated with impaired neurocognitive recovery in acute traumatic brain injury (TBI) patients. There is sparse amount of literature reporting the impact of HIV/AIDS on outcomes in this population. This study aims to further investigate the common comorbidity of HIV/AIDS and its effects on the outcomes of short-term in-hospital patients after acute TBI.
This retrospective cohort study utilized the Nationwide Inpatient Sample to identify patients(18+) from 2012-2014 with a primary diagnosis of acute TBI. ICD-9 codes were used to identify patients with HIV/AIDS and to exclude patients with history of TBI, diabetes insipidus, or missing identifiers(age, gender, death). Data analyses assessed length of stay(LOS), total hospital charges, age of admission and mortality.
Nationwide Inpatient Sample Administrative Database,2012-2014
Participants (or Animals, Specimens, Cadavers) :
Patient encounters documented in Nationwide Inpatient Sample Database.
Interventions : Interventions:Not applicable.
Main Outcome Measure(s) :
Mortality, total in-hospital charges, length of stay, age of admission.
Of the 26,628 with a primary diagnosis of acute TBI, 176 patients were pre-disposed with HIV/AIDS. In comparison to patients without PVD, significant increases were observed in the PVD group:
Patients with concomitant HIV/AIDS who are diagnosed with acute TBI suffer from increased LOS, total charges and mortality. The results of this study can aid clinicians in making clinical decisions within this population. Limitations include inability to determine severity of HIV/AIDS or TBI. Peri-procedural optimization of symptomatic patients is one avenue to improve patient outcomes.
Andrew Dang– Anatomy Fellow, Kansas City University of Medicine and Biosciences, Kansas City, Missouri
Derek Schirmer– Anatomy Fellow, Kansas city university of medicine and Biosciences, Kansas City, Missouri
Russell Arellanes– Anatomy fellow, Kansas City University of Medicine and Biosciences, Kansas City, Missouri
Barth Wright– Professor, Chair, Dept. of Anatomy, Kansas City University of Medicine and Biosciences, Kansas City, Missouri