Category: Measurement; Neurodegenerative Disease (e.g. MS, Parkinson's disease); Technology (e.g. robotics, assistive technology, mHealth)
Objective : The purpose of this study was to validate pupillary response against EEG during dual-tasking postural control.
Design : Cross-sectional study
Setting : Subjects were tested at the University of Kansas Medical Center Hoglund Brain Imaging Center.
Participants (or Animals, Specimens, Cadavers) : Fifteen healthy young adults [age: 25.4±2.5; sex: 10 males]
Interventions : Participants were asked to stand on a balance platform while performing the 2-back auditory test with eyes open and eyes occluded. Each task was 320 seconds. At the same time, participants wore eyetracking glasses to record pupillary response and a high definition EEG cap to record event-related potentials (ERP).
Main Outcome Measure(s) : Outcome measures were pupillary response and ERP latency data.
There were significant changes in peak pupillary response (p=.004) and peak ERP latency (p=.048) from eyes open to eyes occluded. A strong correlation coefficient was observed between peak pupillary response and peak ERP latency (r= -.70, p=.008).
Pupillary response demonstrated strong convergent validity against EEG during dual-tasking postural control. In the future, pupillary response could be used to understand the amount of cognitive workload during postural control in people with neurological deficits.
Melike Kahya– Graduate Student, University of Kansas Medical Center, Kansas City, Kansas
Ke Liao– Senior Scientist, University of Kansas Medical Center, Kansas City, Kansas
Kathleen Gustafson– Research Associate Professor, University of Kansas Medical Center, Kansas City, Kansas
Abiodun Akinwuntan– Dean and Professor, University of Kansas Medical Center, Kansas City, Kansas
Hannes Devos– Assistant Professor, University of Kansas Medical Center, Kansas City, Kansas