Category: Measurement; Neurodegenerative Disease (e.g. MS, Parkinson's disease); Technology (e.g. robotics, assistive technology, mHealth)
Objective : The purpose of this study was to validate pupillary response against EEG during dual-tasking postural control.
Design : Cross-sectional study
Setting : Subjects were tested at the University of Kansas Medical Center Hoglund Brain Imaging Center.
Participants (or Animals, Specimens, Cadavers) : Fifteen healthy young adults [age: 25.4±2.5; sex: 10 males]
Interventions : Participants were asked to stand on a balance platform while performing the 2-back auditory test with eyes open and eyes occluded. Each task was 320 seconds. At the same time, participants wore eyetracking glasses to record pupillary response and a high definition EEG cap to record event-related potentials (ERP).
Main Outcome Measure(s) : Outcome measures were pupillary response and ERP latency data.
Results :
There were significant changes in peak pupillary response (p=.004) and peak ERP latency (p=.048) from eyes open to eyes occluded. A strong correlation coefficient was observed between peak pupillary response and peak ERP latency (r= -.70, p=.008).
Conclusions :
Pupillary response demonstrated strong convergent validity against EEG during dual-tasking postural control. In the future, pupillary response could be used to understand the amount of cognitive workload during postural control in people with neurological deficits.
Melike Kahya
– Graduate Student, University of Kansas Medical Center, Kansas City, KansasKe Liao
– Senior Scientist, University of Kansas Medical Center, Kansas City, KansasKathleen Gustafson
– Research Associate Professor, University of Kansas Medical Center, Kansas City, Kansas
Abiodun Akinwuntan
– Dean and Professor, University of Kansas Medical Center, Kansas City, Kansas
Hannes Devos
– Assistant Professor, University of Kansas Medical Center, Kansas City, Kansas