Category: Measurement; Clinical Practice (assessment, diagnosis, treatment, knowledge translation/EBP, implementation science, program development)
Objective : Multiple Organ Dysfunction Syndrome (MODS) is a systemic physiological disorder affecting ≥2 organ systems triggered after an insult complication. The aims were 1) to compare a group of patients with MODS 6-months after Intensive Care Unit (ICU) discharge, and a group of healthy control in neuropsychological and quality of life (QoL) measures, and 2) to determine the relationship between neuropsychological performance and QoL.
Design : Cross-sectional (6-months after discharge) comparative (control vs MODS group) study.
Setting : Cruces University Hospital, Spain.
Participants (or Animals, Specimens, Cadavers) : 18 patients with MODS at 6-months after ICU discharge and 17 healthy controls (matched by age, sex and years of education)
Interventions : Not applicable.
Main Outcome Measure(s) : Both groups completed the following test: Rey Figure Test, Verbal Fluency Test, Hopkins Verbal Learning Test-Revised, Stroop Test, Modified Wisconsin Card Sorting Test, Trail Making Test, Brief Test of Attention, Symbol Digit Modality Test, Boston Naming Test, and 36-Item Short Form Survey.
Results : A series of independent Student- t showed not significant differences between groups in neuropsychological test-scores, however significant differences were found for QoL total score, physical functioning, and role-physical subscales test-scores (p’sp'sp'sp's
Conclusions : Clinicians should be aware of poor QoL of patients with MODS 6 months after ICU discharge. Moreover, they should realize how attention, processing speed and executive functioning are related to QoL in this population.
Diego Rivera– Researcher, Biocruces Bizkaia Research Health Institute, Barakaldo, Pais Vasco
Itziar Benito-Sánchez– Student, Biocruces Bizkaia Research Health Institute, Barakaldo, Pais Vasco
Antonio Jiménez-Marín– PhD Student, Biocruces Bizkaia Research Health Institute, Barakaldo, Pais Vasco
Fermin Labayen– Medical Doctor, Cruces University Hospital, Barakaldo, Pais Vasco
Victoria Boado– Medical doctor, Cruces University Hospital, Barakaldo, Pais Vasco
Jesus M. Cortes– Research professor, Biocruces Bizkaia Research Health Institute, Barakaldo, Pais Vasco
Juan Carlos Arango-Lasprilla– Ikerbasque Research Professor, Ikerbasque; Biocruces Vizcaya Health Research Institute, Barakaldo, Pais Vasco